| Full name: DEAD-box helicase 17 | Alias Symbol: P72 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 10521 | HGNC ID: HGNC:2740 | Ensembl Gene: ENSG00000100201 | OMIM ID: 608469 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DDX17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX17 | 10521 | 208718_at | -0.1193 | 0.5862 | |
| GSE20347 | DDX17 | 10521 | 208718_at | 0.2138 | 0.0196 | |
| GSE23400 | DDX17 | 10521 | 208718_at | 0.1809 | 0.0019 | |
| GSE26886 | DDX17 | 10521 | 208718_at | -0.0824 | 0.5718 | |
| GSE29001 | DDX17 | 10521 | 208718_at | 0.1096 | 0.5121 | |
| GSE38129 | DDX17 | 10521 | 208718_at | 0.0432 | 0.6917 | |
| GSE45670 | DDX17 | 10521 | 208718_at | -0.0906 | 0.4534 | |
| GSE53622 | DDX17 | 10521 | 400 | -0.1394 | 0.0047 | |
| GSE53624 | DDX17 | 10521 | 400 | -0.1289 | 0.0030 | |
| GSE63941 | DDX17 | 10521 | 208718_at | 0.1095 | 0.7131 | |
| GSE77861 | DDX17 | 10521 | 208718_at | 0.3697 | 0.1166 | |
| GSE97050 | DDX17 | 10521 | A_23_P218784 | -0.0852 | 0.6654 | |
| SRP007169 | DDX17 | 10521 | RNAseq | 0.0524 | 0.8629 | |
| SRP008496 | DDX17 | 10521 | RNAseq | -0.0152 | 0.9132 | |
| SRP064894 | DDX17 | 10521 | RNAseq | -0.0282 | 0.8647 | |
| SRP133303 | DDX17 | 10521 | RNAseq | -0.2693 | 0.0013 | |
| SRP159526 | DDX17 | 10521 | RNAseq | -0.3380 | 0.1048 | |
| SRP193095 | DDX17 | 10521 | RNAseq | -0.1263 | 0.1058 | |
| SRP219564 | DDX17 | 10521 | RNAseq | -0.1362 | 0.5821 | |
| TCGA | DDX17 | 10521 | RNAseq | -0.1317 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDX17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX17 | 10521 | 6 | 5 | 19 | |
| GSE20123 | DDX17 | 10521 | 6 | 4 | 20 | |
| GSE43470 | DDX17 | 10521 | 5 | 5 | 33 | |
| GSE46452 | DDX17 | 10521 | 32 | 2 | 25 | |
| GSE47630 | DDX17 | 10521 | 9 | 4 | 27 | |
| GSE54993 | DDX17 | 10521 | 3 | 6 | 61 | |
| GSE54994 | DDX17 | 10521 | 9 | 7 | 37 | |
| GSE60625 | DDX17 | 10521 | 5 | 0 | 6 | |
| GSE74703 | DDX17 | 10521 | 5 | 4 | 27 | |
| GSE74704 | DDX17 | 10521 | 3 | 2 | 15 | |
| TCGA | DDX17 | 10521 | 28 | 15 | 53 |
Total number of gains: 111; Total number of losses: 54; Total Number of normals: 323.
Somatic mutations of DDX17:
Generating mutation plots.
Highly correlated genes for DDX17:
Showing top 20/371 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX17 | SRSF4 | 0.745365 | 3 | 0 | 3 |
| DDX17 | MZF1 | 0.74276 | 3 | 0 | 3 |
| DDX17 | ZNF358 | 0.730256 | 3 | 0 | 3 |
| DDX17 | SLC7A6 | 0.719534 | 3 | 0 | 3 |
| DDX17 | ZNF546 | 0.707797 | 4 | 0 | 3 |
| DDX17 | ZDHHC7 | 0.696386 | 3 | 0 | 3 |
| DDX17 | UCKL1 | 0.695843 | 3 | 0 | 3 |
| DDX17 | ZNF703 | 0.693512 | 3 | 0 | 3 |
| DDX17 | FAM89B | 0.690588 | 3 | 0 | 3 |
| DDX17 | DNAJC13 | 0.68016 | 3 | 0 | 3 |
| DDX17 | CRKL | 0.678876 | 3 | 0 | 3 |
| DDX17 | ILK | 0.678773 | 4 | 0 | 4 |
| DDX17 | SEPHS1 | 0.670658 | 3 | 0 | 3 |
| DDX17 | CD83 | 0.666425 | 3 | 0 | 3 |
| DDX17 | ASAP2 | 0.666368 | 3 | 0 | 3 |
| DDX17 | PRKACA | 0.666041 | 3 | 0 | 3 |
| DDX17 | ZCCHC24 | 0.663165 | 4 | 0 | 3 |
| DDX17 | DPF2 | 0.663094 | 4 | 0 | 3 |
| DDX17 | GDI1 | 0.661609 | 4 | 0 | 3 |
| DDX17 | KIF3C | 0.660154 | 3 | 0 | 3 |
For details and further investigation, click here
