| Full name: myeloid zinc finger 1 | Alias Symbol: ZSCAN6|MZF1B|MZF-1|Zfp98 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 7593 | HGNC ID: HGNC:13108 | Ensembl Gene: ENSG00000099326 | OMIM ID: 194550 |
Screen Evidence:
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Expression of MZF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MZF1 | 7593 | 40569_at | -0.3799 | 0.4866 | |
| GSE20347 | MZF1 | 7593 | 40569_at | -0.2678 | 0.1078 | |
| GSE23400 | MZF1 | 7593 | 40569_at | -0.1816 | 0.0015 | |
| GSE26886 | MZF1 | 7593 | 40569_at | 0.6153 | 0.0009 | |
| GSE29001 | MZF1 | 7593 | 40569_at | -0.2532 | 0.5441 | |
| GSE38129 | MZF1 | 7593 | 40569_at | -0.2787 | 0.0323 | |
| GSE45670 | MZF1 | 7593 | 40569_at | -0.3302 | 0.0267 | |
| GSE63941 | MZF1 | 7593 | 40569_at | -0.6308 | 0.2241 | |
| GSE77861 | MZF1 | 7593 | 210336_x_at | -0.1624 | 0.3521 | |
| GSE97050 | MZF1 | 7593 | A_33_P3243168 | -0.1576 | 0.4640 | |
| SRP007169 | MZF1 | 7593 | RNAseq | -1.3914 | 0.0192 | |
| SRP064894 | MZF1 | 7593 | RNAseq | 0.1234 | 0.5820 | |
| SRP133303 | MZF1 | 7593 | RNAseq | -0.7113 | 0.0001 | |
| SRP159526 | MZF1 | 7593 | RNAseq | -0.3308 | 0.3678 | |
| SRP193095 | MZF1 | 7593 | RNAseq | -0.1154 | 0.4947 | |
| SRP219564 | MZF1 | 7593 | RNAseq | -0.2801 | 0.4354 | |
| TCGA | MZF1 | 7593 | RNAseq | -0.2516 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MZF1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MZF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MZF1 | 7593 | 2 | 5 | 23 | |
| GSE20123 | MZF1 | 7593 | 2 | 4 | 24 | |
| GSE43470 | MZF1 | 7593 | 3 | 9 | 31 | |
| GSE46452 | MZF1 | 7593 | 45 | 1 | 13 | |
| GSE47630 | MZF1 | 7593 | 7 | 6 | 27 | |
| GSE54993 | MZF1 | 7593 | 18 | 4 | 48 | |
| GSE54994 | MZF1 | 7593 | 5 | 12 | 36 | |
| GSE60625 | MZF1 | 7593 | 9 | 0 | 2 | |
| GSE74703 | MZF1 | 7593 | 3 | 6 | 27 | |
| GSE74704 | MZF1 | 7593 | 2 | 1 | 17 | |
| TCGA | MZF1 | 7593 | 20 | 19 | 57 |
Total number of gains: 116; Total number of losses: 67; Total Number of normals: 305.
Somatic mutations of MZF1:
Generating mutation plots.
Highly correlated genes for MZF1:
Showing top 20/334 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MZF1 | CTF1 | 0.794132 | 3 | 0 | 3 |
| MZF1 | ZNF408 | 0.786859 | 3 | 0 | 3 |
| MZF1 | BCORL1 | 0.780599 | 3 | 0 | 3 |
| MZF1 | C19orf54 | 0.776967 | 3 | 0 | 3 |
| MZF1 | ZFYVE9 | 0.762848 | 3 | 0 | 3 |
| MZF1 | CPA6 | 0.746665 | 3 | 0 | 3 |
| MZF1 | TMEM51 | 0.746283 | 3 | 0 | 3 |
| MZF1 | NFIA | 0.745493 | 3 | 0 | 3 |
| MZF1 | DDX17 | 0.74276 | 3 | 0 | 3 |
| MZF1 | GSK3A | 0.736623 | 4 | 0 | 3 |
| MZF1 | SAMD4B | 0.735267 | 4 | 0 | 3 |
| MZF1 | ZMAT1 | 0.735114 | 3 | 0 | 3 |
| MZF1 | KCNAB2 | 0.731703 | 3 | 0 | 3 |
| MZF1 | SORBS3 | 0.729067 | 3 | 0 | 3 |
| MZF1 | TMEM121 | 0.724333 | 3 | 0 | 3 |
| MZF1 | HABP4 | 0.72415 | 3 | 0 | 3 |
| MZF1 | KCNC4 | 0.720421 | 3 | 0 | 3 |
| MZF1 | CABIN1 | 0.719823 | 4 | 0 | 3 |
| MZF1 | SERPINF2 | 0.716296 | 3 | 0 | 3 |
| MZF1 | FIBCD1 | 0.71436 | 3 | 0 | 3 |
For details and further investigation, click here
