| Full name: solute carrier family 7 member 6 | Alias Symbol: y+LAT-2|KIAA0245|LAT3|LAT-2 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 9057 | HGNC ID: HGNC:11064 | Ensembl Gene: ENSG00000103064 | OMIM ID: 605641 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC7A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC7A6 | 9057 | 203580_s_at | 0.6275 | 0.1936 | |
| GSE20347 | SLC7A6 | 9057 | 203580_s_at | 0.8596 | 0.0000 | |
| GSE23400 | SLC7A6 | 9057 | 203580_s_at | 0.3858 | 0.0000 | |
| GSE26886 | SLC7A6 | 9057 | 203580_s_at | 0.7520 | 0.0108 | |
| GSE29001 | SLC7A6 | 9057 | 203580_s_at | 0.9640 | 0.0115 | |
| GSE38129 | SLC7A6 | 9057 | 203580_s_at | 0.7704 | 0.0000 | |
| GSE45670 | SLC7A6 | 9057 | 203580_s_at | 0.4754 | 0.0196 | |
| GSE53622 | SLC7A6 | 9057 | 121188 | 0.5023 | 0.0000 | |
| GSE53624 | SLC7A6 | 9057 | 121188 | 0.8325 | 0.0000 | |
| GSE63941 | SLC7A6 | 9057 | 203580_s_at | -0.3231 | 0.6193 | |
| GSE77861 | SLC7A6 | 9057 | 203580_s_at | 0.5203 | 0.0786 | |
| GSE97050 | SLC7A6 | 9057 | A_24_P159312 | 0.2236 | 0.3196 | |
| SRP007169 | SLC7A6 | 9057 | RNAseq | 1.4147 | 0.0001 | |
| SRP008496 | SLC7A6 | 9057 | RNAseq | 1.7806 | 0.0000 | |
| SRP064894 | SLC7A6 | 9057 | RNAseq | 0.6016 | 0.0263 | |
| SRP133303 | SLC7A6 | 9057 | RNAseq | 0.7465 | 0.0000 | |
| SRP159526 | SLC7A6 | 9057 | RNAseq | 0.5563 | 0.0704 | |
| SRP193095 | SLC7A6 | 9057 | RNAseq | 1.0223 | 0.0000 | |
| SRP219564 | SLC7A6 | 9057 | RNAseq | 0.2454 | 0.5867 | |
| TCGA | SLC7A6 | 9057 | RNAseq | 0.0659 | 0.2685 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SLC7A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC7A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC7A6 | 9057 | 9 | 2 | 19 | |
| GSE20123 | SLC7A6 | 9057 | 9 | 2 | 19 | |
| GSE43470 | SLC7A6 | 9057 | 1 | 9 | 33 | |
| GSE46452 | SLC7A6 | 9057 | 38 | 1 | 20 | |
| GSE47630 | SLC7A6 | 9057 | 11 | 8 | 21 | |
| GSE54993 | SLC7A6 | 9057 | 2 | 4 | 64 | |
| GSE54994 | SLC7A6 | 9057 | 8 | 10 | 35 | |
| GSE60625 | SLC7A6 | 9057 | 4 | 0 | 7 | |
| GSE74703 | SLC7A6 | 9057 | 1 | 6 | 29 | |
| GSE74704 | SLC7A6 | 9057 | 5 | 1 | 14 | |
| TCGA | SLC7A6 | 9057 | 31 | 12 | 53 |
Total number of gains: 119; Total number of losses: 55; Total Number of normals: 314.
Somatic mutations of SLC7A6:
Generating mutation plots.
Highly correlated genes for SLC7A6:
Showing top 20/1368 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC7A6 | SBNO1 | 0.855909 | 3 | 0 | 3 |
| SLC7A6 | SPNS1 | 0.790051 | 3 | 0 | 3 |
| SLC7A6 | SH3RF3 | 0.766774 | 3 | 0 | 3 |
| SLC7A6 | XPO7 | 0.766472 | 4 | 0 | 4 |
| SLC7A6 | RPS19BP1 | 0.761322 | 3 | 0 | 3 |
| SLC7A6 | TM2D2 | 0.758705 | 3 | 0 | 3 |
| SLC7A6 | CPT1A | 0.756976 | 3 | 0 | 3 |
| SLC7A6 | ACACA | 0.746703 | 3 | 0 | 3 |
| SLC7A6 | SLC7A6OS | 0.73842 | 4 | 0 | 4 |
| SLC7A6 | UHRF1BP1 | 0.736045 | 3 | 0 | 3 |
| SLC7A6 | PMS1 | 0.734785 | 3 | 0 | 3 |
| SLC7A6 | SEC22C | 0.733927 | 3 | 0 | 3 |
| SLC7A6 | L3MBTL3 | 0.733875 | 3 | 0 | 3 |
| SLC7A6 | DDX20 | 0.732563 | 3 | 0 | 3 |
| SLC7A6 | COMMD7 | 0.725431 | 3 | 0 | 3 |
| SLC7A6 | DDX17 | 0.719534 | 3 | 0 | 3 |
| SLC7A6 | LIG3 | 0.713621 | 4 | 0 | 3 |
| SLC7A6 | BRDT | 0.711982 | 3 | 0 | 3 |
| SLC7A6 | KRTCAP2 | 0.710835 | 4 | 0 | 4 |
| SLC7A6 | ZNF703 | 0.710436 | 4 | 0 | 3 |
For details and further investigation, click here
