| Full name: kinesin family member 3C | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 3797 | HGNC ID: HGNC:6321 | Ensembl Gene: ENSG00000084731 | OMIM ID: 602845 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF3C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF3C | 3797 | 203390_s_at | 0.5705 | 0.1621 | |
| GSE20347 | KIF3C | 3797 | 203390_s_at | 0.6879 | 0.0001 | |
| GSE23400 | KIF3C | 3797 | 203390_s_at | 0.2359 | 0.0000 | |
| GSE26886 | KIF3C | 3797 | 203389_at | 0.1691 | 0.2904 | |
| GSE29001 | KIF3C | 3797 | 203390_s_at | 0.6582 | 0.0019 | |
| GSE38129 | KIF3C | 3797 | 203390_s_at | 0.6569 | 0.0000 | |
| GSE45670 | KIF3C | 3797 | 203390_s_at | 1.0964 | 0.0001 | |
| GSE53622 | KIF3C | 3797 | 62682 | 1.1875 | 0.0000 | |
| GSE53624 | KIF3C | 3797 | 62682 | 1.4553 | 0.0000 | |
| GSE63941 | KIF3C | 3797 | 203390_s_at | -1.2134 | 0.0395 | |
| GSE77861 | KIF3C | 3797 | 203389_at | -0.0860 | 0.4612 | |
| GSE97050 | KIF3C | 3797 | A_33_P3369158 | 0.4296 | 0.2807 | |
| SRP007169 | KIF3C | 3797 | RNAseq | 5.3403 | 0.0001 | |
| SRP064894 | KIF3C | 3797 | RNAseq | 1.6019 | 0.0000 | |
| SRP133303 | KIF3C | 3797 | RNAseq | 1.5743 | 0.0000 | |
| SRP159526 | KIF3C | 3797 | RNAseq | 1.9471 | 0.0000 | |
| SRP193095 | KIF3C | 3797 | RNAseq | 2.1507 | 0.0000 | |
| SRP219564 | KIF3C | 3797 | RNAseq | 0.5158 | 0.2372 | |
| TCGA | KIF3C | 3797 | RNAseq | 0.5499 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by KIF3C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF3C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF3C | 3797 | 11 | 2 | 17 | |
| GSE20123 | KIF3C | 3797 | 11 | 2 | 17 | |
| GSE43470 | KIF3C | 3797 | 3 | 1 | 39 | |
| GSE46452 | KIF3C | 3797 | 3 | 4 | 52 | |
| GSE47630 | KIF3C | 3797 | 8 | 0 | 32 | |
| GSE54993 | KIF3C | 3797 | 0 | 6 | 64 | |
| GSE54994 | KIF3C | 3797 | 10 | 0 | 43 | |
| GSE60625 | KIF3C | 3797 | 0 | 3 | 8 | |
| GSE74703 | KIF3C | 3797 | 3 | 0 | 33 | |
| GSE74704 | KIF3C | 3797 | 9 | 1 | 10 | |
| TCGA | KIF3C | 3797 | 36 | 3 | 57 |
Total number of gains: 94; Total number of losses: 22; Total Number of normals: 372.
Somatic mutations of KIF3C:
Generating mutation plots.
Highly correlated genes for KIF3C:
Showing top 20/1001 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF3C | FADS1 | 0.815294 | 3 | 0 | 3 |
| KIF3C | XPR1 | 0.77804 | 5 | 0 | 5 |
| KIF3C | SCNM1 | 0.771292 | 3 | 0 | 3 |
| KIF3C | RAB34 | 0.768153 | 3 | 0 | 3 |
| KIF3C | NF1 | 0.766573 | 3 | 0 | 3 |
| KIF3C | WDR54 | 0.749958 | 6 | 0 | 5 |
| KIF3C | PDE7A | 0.74068 | 4 | 0 | 4 |
| KIF3C | PYCR2 | 0.738981 | 3 | 0 | 3 |
| KIF3C | NEDD1 | 0.738006 | 4 | 0 | 4 |
| KIF3C | USP42 | 0.736045 | 5 | 0 | 5 |
| KIF3C | UTP23 | 0.735017 | 3 | 0 | 3 |
| KIF3C | EHD1 | 0.73405 | 3 | 0 | 3 |
| KIF3C | HAS3 | 0.729373 | 3 | 0 | 3 |
| KIF3C | CYTH3 | 0.724723 | 3 | 0 | 3 |
| KIF3C | C18orf54 | 0.719433 | 5 | 0 | 5 |
| KIF3C | CEP170 | 0.715369 | 3 | 0 | 3 |
| KIF3C | LPCAT1 | 0.71386 | 9 | 0 | 7 |
| KIF3C | IRF2BPL | 0.711896 | 4 | 0 | 4 |
| KIF3C | DGKD | 0.711205 | 4 | 0 | 3 |
| KIF3C | GABRR2 | 0.707874 | 3 | 0 | 3 |
For details and further investigation, click here
