DPF2

 

Full name: double PHD fingers 2 Alias Symbol: ubi-d4|BAF45d
Type: protein-coding gene Cytoband: 11q13.1
Entrez ID: 5977 HGNC ID: HGNC:9964 Ensembl Gene: ENSG00000133884 OMIM ID: 601671
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of DPF2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DPF2 5977 202116_at -0.0338 0.9200
GSE20347 DPF2 5977 202116_at 0.4006 0.0136
GSE23400 DPF2 5977 202116_at 0.3432 0.0000
GSE26886 DPF2 5977 202116_at 0.0779 0.7758
GSE29001 DPF2 5977 202116_at 0.4347 0.0648
GSE38129 DPF2 5977 202116_at 0.2568 0.0739
GSE45670 DPF2 5977 202116_at 0.0921 0.4669
GSE53622 DPF2 5977 16810 0.3902 0.0000
GSE53624 DPF2 5977 16810 0.6292 0.0000
GSE63941 DPF2 5977 202116_at 0.7344 0.0944
GSE77861 DPF2 5977 202116_at 0.4371 0.0180
GSE97050 DPF2 5977 A_23_P127446 -0.1384 0.5484
SRP007169 DPF2 5977 RNAseq 0.1983 0.5054
SRP008496 DPF2 5977 RNAseq 0.1288 0.5357
SRP064894 DPF2 5977 RNAseq 0.2198 0.0204
SRP133303 DPF2 5977 RNAseq 0.3207 0.1337
SRP159526 DPF2 5977 RNAseq 0.4581 0.0339
SRP193095 DPF2 5977 RNAseq 0.5054 0.0000
SRP219564 DPF2 5977 RNAseq 0.1231 0.7014
TCGA DPF2 5977 RNAseq 0.0888 0.0707

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by DPF2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of DPF2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DPF2 5977 8 5 17
GSE20123 DPF2 5977 8 5 17
GSE43470 DPF2 5977 4 1 38
GSE46452 DPF2 5977 11 3 45
GSE47630 DPF2 5977 7 5 28
GSE54993 DPF2 5977 3 0 67
GSE54994 DPF2 5977 7 5 41
GSE60625 DPF2 5977 0 3 8
GSE74703 DPF2 5977 3 0 33
GSE74704 DPF2 5977 6 3 11
TCGA DPF2 5977 23 7 66

Total number of gains: 80; Total number of losses: 37; Total Number of normals: 371.  


 

Somatic mutations of DPF2:

 

Generating mutation plots.

 

Highly correlated genes for DPF2:

 

Showing top 20/887 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DPF2CASC40.785988303
DPF2RAB340.773362303
DPF2SPOPL0.750857303
DPF2ANTXR20.740026303
DPF2CFL20.737441303
DPF2SMTN0.733781303
DPF2ATXN1L0.730831303
DPF2MTMR110.724451404
DPF2PSMG30.723319303
DPF2JMY0.72184303
DPF2PLEKHA30.715152303
DPF2MTCP10.712677303
DPF2PTGFRN0.711459403
DPF2TRIB10.709559404
DPF2GRAMD1A0.707763404
DPF2INO80E0.700948303
DPF2DCAF70.696978403
DPF2ZNF6910.696438404
DPF2TEAD20.693631303
DPF2TFIP110.692943303

For details and further investigation, click here