| Full name: family with sequence similarity 89 member B | Alias Symbol: MTVR1|LRAP25 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 23625 | HGNC ID: HGNC:16708 | Ensembl Gene: ENSG00000176973 | OMIM ID: 616128 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM89B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM89B | 23625 | 32209_at | 0.4484 | 0.1168 | |
| GSE20347 | FAM89B | 23625 | 32209_at | 0.1411 | 0.2846 | |
| GSE23400 | FAM89B | 23625 | 32209_at | 0.0856 | 0.0755 | |
| GSE26886 | FAM89B | 23625 | 32209_at | -0.0724 | 0.8151 | |
| GSE29001 | FAM89B | 23625 | 32209_at | 0.0582 | 0.8612 | |
| GSE38129 | FAM89B | 23625 | 32209_at | 0.0539 | 0.6025 | |
| GSE45670 | FAM89B | 23625 | 32209_at | 0.1675 | 0.0720 | |
| GSE53622 | FAM89B | 23625 | 20801 | 0.1317 | 0.0494 | |
| GSE53624 | FAM89B | 23625 | 20801 | 0.2890 | 0.0000 | |
| GSE63941 | FAM89B | 23625 | 32209_at | 0.0492 | 0.9131 | |
| GSE77861 | FAM89B | 23625 | 32209_at | 0.2730 | 0.0974 | |
| GSE97050 | FAM89B | 23625 | A_33_P3220612 | -0.0703 | 0.7371 | |
| SRP007169 | FAM89B | 23625 | RNAseq | -1.5835 | 0.0001 | |
| SRP008496 | FAM89B | 23625 | RNAseq | -1.0297 | 0.0006 | |
| SRP064894 | FAM89B | 23625 | RNAseq | 0.1181 | 0.6811 | |
| SRP133303 | FAM89B | 23625 | RNAseq | 0.3720 | 0.1118 | |
| SRP159526 | FAM89B | 23625 | RNAseq | 0.1695 | 0.4577 | |
| SRP193095 | FAM89B | 23625 | RNAseq | 0.0231 | 0.8773 | |
| SRP219564 | FAM89B | 23625 | RNAseq | -0.3497 | 0.2744 | |
| TCGA | FAM89B | 23625 | RNAseq | 0.1246 | 0.0206 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FAM89B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM89B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM89B | 23625 | 8 | 5 | 17 | |
| GSE20123 | FAM89B | 23625 | 8 | 5 | 17 | |
| GSE43470 | FAM89B | 23625 | 4 | 1 | 38 | |
| GSE46452 | FAM89B | 23625 | 11 | 3 | 45 | |
| GSE47630 | FAM89B | 23625 | 7 | 5 | 28 | |
| GSE54993 | FAM89B | 23625 | 3 | 0 | 67 | |
| GSE54994 | FAM89B | 23625 | 7 | 5 | 41 | |
| GSE60625 | FAM89B | 23625 | 0 | 3 | 8 | |
| GSE74703 | FAM89B | 23625 | 3 | 0 | 33 | |
| GSE74704 | FAM89B | 23625 | 6 | 3 | 11 | |
| TCGA | FAM89B | 23625 | 23 | 7 | 66 |
Total number of gains: 80; Total number of losses: 37; Total Number of normals: 371.
Somatic mutations of FAM89B:
Generating mutation plots.
Highly correlated genes for FAM89B:
Showing top 20/619 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM89B | RPAP1 | 0.80968 | 3 | 0 | 3 |
| FAM89B | ADCY3 | 0.809005 | 3 | 0 | 3 |
| FAM89B | CERS2 | 0.801161 | 3 | 0 | 3 |
| FAM89B | MARK1 | 0.800931 | 3 | 0 | 3 |
| FAM89B | PCYT1A | 0.79544 | 3 | 0 | 3 |
| FAM89B | PKN3 | 0.786438 | 3 | 0 | 3 |
| FAM89B | KCNS3 | 0.782275 | 3 | 0 | 3 |
| FAM89B | NTPCR | 0.782044 | 3 | 0 | 3 |
| FAM89B | MPG | 0.781242 | 3 | 0 | 3 |
| FAM89B | RAB7A | 0.776231 | 3 | 0 | 3 |
| FAM89B | CIDEB | 0.76555 | 3 | 0 | 3 |
| FAM89B | NGF | 0.761941 | 3 | 0 | 3 |
| FAM89B | NSL1 | 0.761746 | 3 | 0 | 3 |
| FAM89B | PPP1R9B | 0.760323 | 3 | 0 | 3 |
| FAM89B | PRELID1 | 0.758923 | 3 | 0 | 3 |
| FAM89B | TTLL1 | 0.757819 | 3 | 0 | 3 |
| FAM89B | LRP12 | 0.756778 | 3 | 0 | 3 |
| FAM89B | RAB35 | 0.756285 | 3 | 0 | 3 |
| FAM89B | CERS5 | 0.752046 | 3 | 0 | 3 |
| FAM89B | IGF2R | 0.751855 | 4 | 0 | 4 |
For details and further investigation, click here
