| Full name: diacylglycerol kinase gamma | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q27.2-q27.3 | ||
| Entrez ID: 1608 | HGNC ID: HGNC:2853 | Ensembl Gene: ENSG00000058866 | OMIM ID: 601854 |
| Drug and gene relationship at DGIdb | |||
Expression of DGKG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGKG | 1608 | 206395_at | -0.6986 | 0.5159 | |
| GSE20347 | DGKG | 1608 | 206395_at | 0.3300 | 0.0500 | |
| GSE23400 | DGKG | 1608 | 206395_at | -0.1914 | 0.0075 | |
| GSE26886 | DGKG | 1608 | 206395_at | 0.2955 | 0.2888 | |
| GSE29001 | DGKG | 1608 | 206395_at | 0.1150 | 0.7459 | |
| GSE38129 | DGKG | 1608 | 206395_at | 0.0366 | 0.8921 | |
| GSE45670 | DGKG | 1608 | 206395_at | -0.1783 | 0.5507 | |
| GSE53622 | DGKG | 1608 | 14897 | -0.5617 | 0.0421 | |
| GSE53624 | DGKG | 1608 | 14897 | 0.2188 | 0.3007 | |
| GSE63941 | DGKG | 1608 | 206395_at | 0.1736 | 0.5794 | |
| GSE77861 | DGKG | 1608 | 206395_at | 0.2513 | 0.0085 | |
| GSE97050 | DGKG | 1608 | A_33_P3421728 | -1.8286 | 0.1267 | |
| SRP007169 | DGKG | 1608 | RNAseq | 4.6992 | 0.0000 | |
| SRP008496 | DGKG | 1608 | RNAseq | 4.0601 | 0.0000 | |
| SRP064894 | DGKG | 1608 | RNAseq | -0.3057 | 0.3974 | |
| SRP133303 | DGKG | 1608 | RNAseq | -0.2824 | 0.6085 | |
| SRP159526 | DGKG | 1608 | RNAseq | 0.7721 | 0.2887 | |
| SRP193095 | DGKG | 1608 | RNAseq | 2.2807 | 0.0000 | |
| SRP219564 | DGKG | 1608 | RNAseq | -0.5247 | 0.6729 | |
| TCGA | DGKG | 1608 | RNAseq | -0.2506 | 0.3489 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by DGKG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGKG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGKG | 1608 | 25 | 0 | 5 | |
| GSE20123 | DGKG | 1608 | 25 | 0 | 5 | |
| GSE43470 | DGKG | 1608 | 23 | 0 | 20 | |
| GSE46452 | DGKG | 1608 | 19 | 1 | 39 | |
| GSE47630 | DGKG | 1608 | 27 | 2 | 11 | |
| GSE54993 | DGKG | 1608 | 1 | 19 | 50 | |
| GSE54994 | DGKG | 1608 | 40 | 0 | 13 | |
| GSE60625 | DGKG | 1608 | 0 | 6 | 5 | |
| GSE74703 | DGKG | 1608 | 20 | 0 | 16 | |
| GSE74704 | DGKG | 1608 | 17 | 0 | 3 | |
| TCGA | DGKG | 1608 | 77 | 0 | 19 |
Total number of gains: 274; Total number of losses: 28; Total Number of normals: 186.
Somatic mutations of DGKG:
Generating mutation plots.
Highly correlated genes for DGKG:
Showing top 20/585 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGKG | SYNC | 0.780043 | 4 | 0 | 4 |
| DGKG | ZCRB1 | 0.76499 | 3 | 0 | 3 |
| DGKG | TMOD1 | 0.760459 | 5 | 0 | 4 |
| DGKG | DCHS2 | 0.759302 | 3 | 0 | 3 |
| DGKG | LONRF3 | 0.754711 | 3 | 0 | 3 |
| DGKG | STARD13 | 0.7432 | 4 | 0 | 4 |
| DGKG | WSCD2 | 0.742735 | 4 | 0 | 3 |
| DGKG | FOXP2 | 0.741929 | 3 | 0 | 3 |
| DGKG | NR4A1 | 0.740731 | 3 | 0 | 3 |
| DGKG | DNAH14 | 0.737665 | 3 | 0 | 3 |
| DGKG | LRCH2 | 0.736691 | 4 | 0 | 4 |
| DGKG | LIFR | 0.728906 | 3 | 0 | 3 |
| DGKG | SLC35F1 | 0.728419 | 3 | 0 | 3 |
| DGKG | CORO6 | 0.726645 | 3 | 0 | 3 |
| DGKG | AGTR1 | 0.723918 | 4 | 0 | 4 |
| DGKG | SH3GL2 | 0.717768 | 6 | 0 | 5 |
| DGKG | KLHL15 | 0.709651 | 3 | 0 | 3 |
| DGKG | SGCA | 0.708032 | 6 | 0 | 5 |
| DGKG | PYGM | 0.706849 | 6 | 0 | 5 |
| DGKG | CAMK2G | 0.705246 | 5 | 0 | 4 |
For details and further investigation, click here
