| Full name: zinc finger CCHC-type and RNA binding motif containing 1 | Alias Symbol: MADP-1|MADP1|RBM36|ZCCHC19|SNRNP31 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 85437 | HGNC ID: HGNC:29620 | Ensembl Gene: ENSG00000139168 | OMIM ID: 610750 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZCRB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZCRB1 | 85437 | 225394_s_at | -0.2842 | 0.3648 | |
| GSE26886 | ZCRB1 | 85437 | 225394_s_at | 1.2617 | 0.0000 | |
| GSE45670 | ZCRB1 | 85437 | 227416_s_at | -0.0274 | 0.8076 | |
| GSE53622 | ZCRB1 | 85437 | 27682 | -0.0040 | 0.9565 | |
| GSE53624 | ZCRB1 | 85437 | 27682 | 0.2308 | 0.0005 | |
| GSE63941 | ZCRB1 | 85437 | 227416_s_at | 0.5511 | 0.0763 | |
| GSE77861 | ZCRB1 | 85437 | 225394_s_at | 0.4343 | 0.0063 | |
| GSE97050 | ZCRB1 | A_21_P0013817 | -0.2567 | 0.4886 | ||
| SRP007169 | ZCRB1 | 85437 | RNAseq | 1.2812 | 0.0790 | |
| SRP008496 | ZCRB1 | 85437 | RNAseq | 0.9090 | 0.0671 | |
| SRP064894 | ZCRB1 | 85437 | RNAseq | 0.2567 | 0.2447 | |
| SRP133303 | ZCRB1 | 85437 | RNAseq | 0.5188 | 0.0000 | |
| SRP159526 | ZCRB1 | 85437 | RNAseq | 0.3143 | 0.1332 | |
| SRP193095 | ZCRB1 | 85437 | RNAseq | -0.0338 | 0.7757 | |
| SRP219564 | ZCRB1 | 85437 | RNAseq | -0.3164 | 0.4445 | |
| TCGA | ZCRB1 | 85437 | RNAseq | -0.0437 | 0.3786 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZCRB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZCRB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZCRB1 | 85437 | 4 | 1 | 25 | |
| GSE20123 | ZCRB1 | 85437 | 4 | 1 | 25 | |
| GSE43470 | ZCRB1 | 85437 | 3 | 4 | 36 | |
| GSE46452 | ZCRB1 | 85437 | 8 | 1 | 50 | |
| GSE47630 | ZCRB1 | 85437 | 11 | 2 | 27 | |
| GSE54993 | ZCRB1 | 85437 | 0 | 7 | 63 | |
| GSE54994 | ZCRB1 | 85437 | 7 | 2 | 44 | |
| GSE60625 | ZCRB1 | 85437 | 0 | 0 | 11 | |
| GSE74703 | ZCRB1 | 85437 | 3 | 2 | 31 | |
| GSE74704 | ZCRB1 | 85437 | 2 | 1 | 17 | |
| TCGA | ZCRB1 | 85437 | 15 | 14 | 67 |
Total number of gains: 57; Total number of losses: 35; Total Number of normals: 396.
Somatic mutations of ZCRB1:
Generating mutation plots.
Highly correlated genes for ZCRB1:
Showing top 20/368 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZCRB1 | DDX42 | 0.793626 | 3 | 0 | 3 |
| ZCRB1 | COL4A5 | 0.789343 | 3 | 0 | 3 |
| ZCRB1 | DGKG | 0.76499 | 3 | 0 | 3 |
| ZCRB1 | SEMA3A | 0.747896 | 3 | 0 | 3 |
| ZCRB1 | GNB5 | 0.743873 | 3 | 0 | 3 |
| ZCRB1 | EIF1B | 0.737059 | 3 | 0 | 3 |
| ZCRB1 | LSG1 | 0.730714 | 3 | 0 | 3 |
| ZCRB1 | ZNF358 | 0.726729 | 3 | 0 | 3 |
| ZCRB1 | SRPK2 | 0.726042 | 3 | 0 | 3 |
| ZCRB1 | NFIL3 | 0.719814 | 4 | 0 | 3 |
| ZCRB1 | VPS13C | 0.71919 | 3 | 0 | 3 |
| ZCRB1 | TSPYL2 | 0.714054 | 3 | 0 | 3 |
| ZCRB1 | TRPC1 | 0.711955 | 3 | 0 | 3 |
| ZCRB1 | RIOK1 | 0.709473 | 3 | 0 | 3 |
| ZCRB1 | STK3 | 0.706371 | 3 | 0 | 3 |
| ZCRB1 | LRCH1 | 0.705267 | 3 | 0 | 3 |
| ZCRB1 | TCEAL4 | 0.704975 | 3 | 0 | 3 |
| ZCRB1 | PRNP | 0.704158 | 3 | 0 | 3 |
| ZCRB1 | METTL5 | 0.702058 | 4 | 0 | 3 |
| ZCRB1 | COCH | 0.7018 | 4 | 0 | 3 |
For details and further investigation, click here
