| Full name: syncoilin, intermediate filament protein | Alias Symbol: SYNCOILIN | ||
| Type: protein-coding gene | Cytoband: 1p35.1 | ||
| Entrez ID: 81493 | HGNC ID: HGNC:28897 | Ensembl Gene: ENSG00000162520 | OMIM ID: 611750 |
| Drug and gene relationship at DGIdb | |||
Expression of SYNC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYNC | 81493 | 221276_s_at | -1.4308 | 0.2333 | |
| GSE20347 | SYNC | 81493 | 221276_s_at | -0.2287 | 0.4844 | |
| GSE23400 | SYNC | 81493 | 221276_s_at | -0.1770 | 0.3714 | |
| GSE26886 | SYNC | 81493 | 221276_s_at | -0.0375 | 0.9432 | |
| GSE29001 | SYNC | 81493 | 221276_s_at | 0.1051 | 0.7669 | |
| GSE38129 | SYNC | 81493 | 221276_s_at | -0.6689 | 0.1786 | |
| GSE45670 | SYNC | 81493 | 221276_s_at | -1.0873 | 0.0013 | |
| GSE63941 | SYNC | 81493 | 221276_s_at | -4.9012 | 0.0001 | |
| GSE77861 | SYNC | 81493 | 221276_s_at | -0.0418 | 0.7032 | |
| GSE97050 | SYNC | 81493 | A_23_P96965 | -0.7677 | 0.1585 | |
| SRP007169 | SYNC | 81493 | RNAseq | 0.8305 | 0.1032 | |
| SRP008496 | SYNC | 81493 | RNAseq | 1.4181 | 0.0009 | |
| SRP064894 | SYNC | 81493 | RNAseq | 0.5084 | 0.1919 | |
| SRP133303 | SYNC | 81493 | RNAseq | 0.5259 | 0.3146 | |
| SRP159526 | SYNC | 81493 | RNAseq | -0.4168 | 0.5003 | |
| SRP193095 | SYNC | 81493 | RNAseq | 0.2592 | 0.2333 | |
| SRP219564 | SYNC | 81493 | RNAseq | 0.0904 | 0.9276 | |
| TCGA | SYNC | 81493 | RNAseq | -0.3282 | 0.0697 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by SYNC expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SYNC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYNC | 81493 | 2 | 5 | 23 | |
| GSE20123 | SYNC | 81493 | 2 | 4 | 24 | |
| GSE43470 | SYNC | 81493 | 5 | 6 | 32 | |
| GSE46452 | SYNC | 81493 | 5 | 1 | 53 | |
| GSE47630 | SYNC | 81493 | 8 | 3 | 29 | |
| GSE54993 | SYNC | 81493 | 1 | 1 | 68 | |
| GSE54994 | SYNC | 81493 | 11 | 2 | 40 | |
| GSE60625 | SYNC | 81493 | 0 | 0 | 11 | |
| GSE74703 | SYNC | 81493 | 4 | 3 | 29 | |
| GSE74704 | SYNC | 81493 | 1 | 0 | 19 | |
| TCGA | SYNC | 81493 | 12 | 18 | 66 |
Total number of gains: 51; Total number of losses: 43; Total Number of normals: 394.
Somatic mutations of SYNC:
Generating mutation plots.
Highly correlated genes for SYNC:
Showing top 20/1089 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYNC | PARD3B | 0.877324 | 3 | 0 | 3 |
| SYNC | PRICKLE2 | 0.869688 | 4 | 0 | 4 |
| SYNC | MRGPRF | 0.869081 | 4 | 0 | 4 |
| SYNC | HMCN1 | 0.851704 | 4 | 0 | 4 |
| SYNC | ANTXR2 | 0.844582 | 4 | 0 | 4 |
| SYNC | ITGA1 | 0.833803 | 7 | 0 | 7 |
| SYNC | SMIM10 | 0.831824 | 3 | 0 | 3 |
| SYNC | AFF3 | 0.828688 | 3 | 0 | 3 |
| SYNC | ASB5 | 0.826682 | 4 | 0 | 4 |
| SYNC | RASSF3 | 0.825599 | 3 | 0 | 3 |
| SYNC | TBX5 | 0.814793 | 4 | 0 | 4 |
| SYNC | DNALI1 | 0.813815 | 5 | 0 | 5 |
| SYNC | C1QTNF7 | 0.812396 | 3 | 0 | 3 |
| SYNC | CLMP | 0.812341 | 4 | 0 | 4 |
| SYNC | TGFB1I1 | 0.812266 | 7 | 0 | 7 |
| SYNC | PHYH | 0.808791 | 4 | 0 | 4 |
| SYNC | CTNNA3 | 0.808328 | 3 | 0 | 3 |
| SYNC | BHMT2 | 0.80814 | 7 | 0 | 7 |
| SYNC | FIBIN | 0.803283 | 4 | 0 | 4 |
| SYNC | ALDH1B1 | 0.800361 | 4 | 0 | 4 |
For details and further investigation, click here
