| Full name: forkhead box P2 | Alias Symbol: CAGH44 | ||
| Type: protein-coding gene | Cytoband: 7q31.1 | ||
| Entrez ID: 93986 | HGNC ID: HGNC:13875 | Ensembl Gene: ENSG00000128573 | OMIM ID: 605317 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXP2 | 93986 | 235201_at | -0.6781 | 0.4574 | |
| GSE26886 | FOXP2 | 93986 | 235201_at | -0.3677 | 0.4804 | |
| GSE45670 | FOXP2 | 93986 | 235201_at | -1.0750 | 0.0370 | |
| GSE53622 | FOXP2 | 93986 | 92196 | -1.0468 | 0.0000 | |
| GSE53624 | FOXP2 | 93986 | 92196 | -1.0896 | 0.0000 | |
| GSE63941 | FOXP2 | 93986 | 1564876_s_at | 0.1114 | 0.2917 | |
| GSE77861 | FOXP2 | 93986 | 235201_at | 0.1967 | 0.7194 | |
| GSE97050 | FOXP2 | 93986 | A_24_P921683 | -1.5019 | 0.1675 | |
| SRP007169 | FOXP2 | 93986 | RNAseq | 0.2269 | 0.6891 | |
| SRP008496 | FOXP2 | 93986 | RNAseq | 0.1440 | 0.7505 | |
| SRP064894 | FOXP2 | 93986 | RNAseq | -0.5642 | 0.0652 | |
| SRP133303 | FOXP2 | 93986 | RNAseq | -0.1468 | 0.7117 | |
| SRP159526 | FOXP2 | 93986 | RNAseq | -0.8147 | 0.0255 | |
| SRP193095 | FOXP2 | 93986 | RNAseq | -0.0265 | 0.9296 | |
| SRP219564 | FOXP2 | 93986 | RNAseq | 0.1345 | 0.8696 | |
| TCGA | FOXP2 | 93986 | RNAseq | -0.3188 | 0.1891 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by FOXP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXP2 | 93986 | 10 | 2 | 18 | |
| GSE20123 | FOXP2 | 93986 | 11 | 2 | 17 | |
| GSE43470 | FOXP2 | 93986 | 3 | 2 | 38 | |
| GSE46452 | FOXP2 | 93986 | 8 | 1 | 50 | |
| GSE47630 | FOXP2 | 93986 | 7 | 4 | 29 | |
| GSE54993 | FOXP2 | 93986 | 2 | 8 | 60 | |
| GSE54994 | FOXP2 | 93986 | 11 | 5 | 37 | |
| GSE60625 | FOXP2 | 93986 | 0 | 0 | 11 | |
| GSE74703 | FOXP2 | 93986 | 3 | 2 | 31 | |
| GSE74704 | FOXP2 | 93986 | 7 | 2 | 11 | |
| TCGA | FOXP2 | 93986 | 35 | 17 | 44 |
Total number of gains: 97; Total number of losses: 45; Total Number of normals: 346.
Somatic mutations of FOXP2:
Generating mutation plots.
Highly correlated genes for FOXP2:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXP2 | FOXN3 | 0.774435 | 3 | 0 | 3 |
| FOXP2 | DGKG | 0.741929 | 3 | 0 | 3 |
| FOXP2 | UST | 0.74152 | 3 | 0 | 3 |
| FOXP2 | ALDH1A2 | 0.740346 | 3 | 0 | 3 |
| FOXP2 | EPM2A | 0.732247 | 4 | 0 | 3 |
| FOXP2 | KLF12 | 0.723749 | 3 | 0 | 3 |
| FOXP2 | PBX1 | 0.718272 | 5 | 0 | 4 |
| FOXP2 | THRB | 0.705705 | 4 | 0 | 3 |
| FOXP2 | PKD2 | 0.702207 | 3 | 0 | 3 |
| FOXP2 | TOB2 | 0.701921 | 3 | 0 | 3 |
| FOXP2 | LPP | 0.691303 | 5 | 0 | 4 |
| FOXP2 | CADM2 | 0.689265 | 4 | 0 | 3 |
| FOXP2 | SLC35F1 | 0.68202 | 3 | 0 | 3 |
| FOXP2 | COL21A1 | 0.678535 | 3 | 0 | 3 |
| FOXP2 | CRYAB | 0.675097 | 4 | 0 | 4 |
| FOXP2 | LMO3 | 0.674219 | 4 | 0 | 3 |
| FOXP2 | RXRG | 0.673395 | 3 | 0 | 3 |
| FOXP2 | CSDE1 | 0.67325 | 3 | 0 | 3 |
| FOXP2 | BCHE | 0.673055 | 5 | 0 | 4 |
| FOXP2 | ROCK1 | 0.670329 | 3 | 0 | 3 |
For details and further investigation, click here
