DCHS2

 

Full name: dachsous cadherin-related 2 Alias Symbol: CDHJ|FLJ20047|PCDHJ|CDHR7
Type: protein-coding gene Cytoband: 4q31.3
Entrez ID: 54798 HGNC ID: HGNC:23111 Ensembl Gene: ENSG00000197410 OMIM ID: 612486
Drug and gene relationship at DGIdb

 

Expression of DCHS2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DCHS2 54798 220373_at 0.0321 0.9518
GSE20347 DCHS2 54798 220373_at 0.1205 0.2099
GSE23400 DCHS2 54798 220373_at -0.0354 0.2941
GSE26886 DCHS2 54798 220373_at 0.3472 0.1724
GSE29001 DCHS2 54798 220373_at 0.0773 0.6931
GSE38129 DCHS2 54798 220373_at -0.0357 0.6744
GSE45670 DCHS2 54798 220373_at 0.1050 0.1482
GSE53622 DCHS2 54798 4346 -0.1305 0.6290
GSE53624 DCHS2 54798 4346 0.0441 0.8427
GSE63941 DCHS2 54798 220373_at 0.2082 0.1196
GSE77861 DCHS2 54798 220373_at -0.0619 0.5920
GSE97050 DCHS2 54798 A_23_P144490 -0.3464 0.4585
SRP007169 DCHS2 54798 RNAseq 5.2675 0.0002
SRP133303 DCHS2 54798 RNAseq -0.3376 0.2259
SRP159526 DCHS2 54798 RNAseq 2.1910 0.0168
TCGA DCHS2 54798 RNAseq -0.7842 0.0310

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by DCHS2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of DCHS2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DCHS2 54798 0 14 16
GSE20123 DCHS2 54798 0 14 16
GSE43470 DCHS2 54798 0 13 30
GSE46452 DCHS2 54798 1 36 22
GSE47630 DCHS2 54798 0 23 17
GSE54993 DCHS2 54798 10 0 60
GSE54994 DCHS2 54798 1 13 39
GSE60625 DCHS2 54798 0 1 10
GSE74703 DCHS2 54798 0 11 25
GSE74704 DCHS2 54798 0 7 13
TCGA DCHS2 54798 10 36 50

Total number of gains: 22; Total number of losses: 168; Total Number of normals: 298.  


 

Somatic mutations of DCHS2:

 

Generating mutation plots.

 

Highly correlated genes for DCHS2:

 

Showing top 20/751 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DCHS2GDI10.806922303
DCHS2ENO20.795627303
DCHS2DGKG0.759302303
DCHS2CDC42EP40.74991303
DCHS2TCAP0.747519303
DCHS2NTNG10.73379404
DCHS2LCE1E0.729579303
DCHS2PRKACA0.718308303
DCHS2SPIB0.711798303
DCHS2NANOS30.708734303
DCHS2C20orf960.706648403
DCHS2ZNF3580.705954404
DCHS2FAM43B0.705582303
DCHS2SLC7A90.7036505
DCHS2LRP5L0.701039303
DCHS2GSX10.700423403
DCHS2PRKCE0.695243504
DCHS2CYP3A40.694071404
DCHS2NAA110.683444606
DCHS2NDP0.681312303

For details and further investigation, click here