| Full name: sarcoglycan alpha | Alias Symbol: SCARMD1|LGMD2D|adhalin|DMDA2|A2 | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 6442 | HGNC ID: HGNC:10805 | Ensembl Gene: ENSG00000108823 | OMIM ID: 600119 |
| Drug and gene relationship at DGIdb | |||
Expression of SGCA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SGCA | 6442 | 210632_s_at | -0.7534 | 0.3617 | |
| GSE20347 | SGCA | 6442 | 210632_s_at | -0.0520 | 0.6755 | |
| GSE23400 | SGCA | 6442 | 210632_s_at | -0.2655 | 0.0000 | |
| GSE26886 | SGCA | 6442 | 210632_s_at | 0.5175 | 0.0379 | |
| GSE29001 | SGCA | 6442 | 210632_s_at | -0.1811 | 0.0944 | |
| GSE38129 | SGCA | 6442 | 210632_s_at | -0.7542 | 0.0047 | |
| GSE45670 | SGCA | 6442 | 210632_s_at | -0.6432 | 0.0000 | |
| GSE53622 | SGCA | 6442 | 31812 | -1.4582 | 0.0000 | |
| GSE53624 | SGCA | 6442 | 31812 | -1.6757 | 0.0000 | |
| GSE63941 | SGCA | 6442 | 210632_s_at | -0.0643 | 0.6528 | |
| GSE77861 | SGCA | 6442 | 210632_s_at | -0.0036 | 0.9854 | |
| GSE97050 | SGCA | 6442 | A_23_P66637 | -1.0184 | 0.1236 | |
| SRP064894 | SGCA | 6442 | RNAseq | -1.2262 | 0.0021 | |
| SRP133303 | SGCA | 6442 | RNAseq | -2.6513 | 0.0000 | |
| SRP159526 | SGCA | 6442 | RNAseq | -0.7556 | 0.2633 | |
| SRP219564 | SGCA | 6442 | RNAseq | -1.0924 | 0.3659 | |
| TCGA | SGCA | 6442 | RNAseq | -1.3330 | 0.0048 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SGCA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SGCA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SGCA | 6442 | 5 | 2 | 23 | |
| GSE20123 | SGCA | 6442 | 5 | 2 | 23 | |
| GSE43470 | SGCA | 6442 | 3 | 2 | 38 | |
| GSE46452 | SGCA | 6442 | 32 | 0 | 27 | |
| GSE47630 | SGCA | 6442 | 9 | 0 | 31 | |
| GSE54993 | SGCA | 6442 | 2 | 4 | 64 | |
| GSE54994 | SGCA | 6442 | 9 | 6 | 38 | |
| GSE60625 | SGCA | 6442 | 4 | 0 | 7 | |
| GSE74703 | SGCA | 6442 | 3 | 2 | 31 | |
| GSE74704 | SGCA | 6442 | 4 | 1 | 15 | |
| TCGA | SGCA | 6442 | 27 | 7 | 62 |
Total number of gains: 103; Total number of losses: 26; Total Number of normals: 359.
Somatic mutations of SGCA:
Generating mutation plots.
Highly correlated genes for SGCA:
Showing top 20/1279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SGCA | CYP21A2 | 0.864581 | 3 | 0 | 3 |
| SGCA | XKR4 | 0.859387 | 5 | 0 | 5 |
| SGCA | ANGPTL1 | 0.85641 | 5 | 0 | 5 |
| SGCA | PGR | 0.843457 | 6 | 0 | 6 |
| SGCA | ADAMTSL1 | 0.837074 | 5 | 0 | 5 |
| SGCA | CLEC3B | 0.834752 | 3 | 0 | 3 |
| SGCA | SORCS1 | 0.834102 | 5 | 0 | 5 |
| SGCA | ITGA7 | 0.827232 | 9 | 0 | 9 |
| SGCA | MIR100HG | 0.815219 | 4 | 0 | 4 |
| SGCA | HSPB7 | 0.814773 | 11 | 0 | 11 |
| SGCA | PDZRN4 | 0.813066 | 9 | 0 | 9 |
| SGCA | MYOC | 0.808807 | 9 | 0 | 9 |
| SGCA | HPSE2 | 0.806588 | 9 | 0 | 9 |
| SGCA | CASQ2 | 0.804654 | 10 | 0 | 10 |
| SGCA | IQUB | 0.799702 | 3 | 0 | 3 |
| SGCA | KCNMB1 | 0.789323 | 10 | 0 | 9 |
| SGCA | PTCHD1 | 0.78753 | 5 | 0 | 5 |
| SGCA | LMOD1 | 0.787153 | 10 | 0 | 10 |
| SGCA | GMPR | 0.7868 | 3 | 0 | 3 |
| SGCA | MRVI1 | 0.786081 | 6 | 0 | 5 |
For details and further investigation, click here
