| Full name: tropomodulin 1 | Alias Symbol: ETMOD | ||
| Type: protein-coding gene | Cytoband: 9q22.33 | ||
| Entrez ID: 7111 | HGNC ID: HGNC:11871 | Ensembl Gene: ENSG00000136842 | OMIM ID: 190930 |
| Drug and gene relationship at DGIdb | |||
Expression of TMOD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMOD1 | 7111 | 203662_s_at | -1.6218 | 0.1943 | |
| GSE20347 | TMOD1 | 7111 | 203661_s_at | 0.1032 | 0.5697 | |
| GSE23400 | TMOD1 | 7111 | 203662_s_at | -0.4574 | 0.0000 | |
| GSE26886 | TMOD1 | 7111 | 203661_s_at | 0.2985 | 0.2229 | |
| GSE29001 | TMOD1 | 7111 | 203662_s_at | -0.2706 | 0.2140 | |
| GSE38129 | TMOD1 | 7111 | 203661_s_at | -0.5062 | 0.0564 | |
| GSE45670 | TMOD1 | 7111 | 203661_s_at | -1.0225 | 0.0000 | |
| GSE63941 | TMOD1 | 7111 | 203662_s_at | -0.8358 | 0.0405 | |
| GSE77861 | TMOD1 | 7111 | 203662_s_at | -0.0129 | 0.9314 | |
| GSE97050 | TMOD1 | 7111 | A_23_P112289 | -1.4861 | 0.0828 | |
| SRP064894 | TMOD1 | 7111 | RNAseq | -0.2668 | 0.5174 | |
| SRP133303 | TMOD1 | 7111 | RNAseq | -2.5388 | 0.0000 | |
| SRP159526 | TMOD1 | 7111 | RNAseq | -0.5150 | 0.2818 | |
| SRP219564 | TMOD1 | 7111 | RNAseq | -0.6808 | 0.5047 | |
| TCGA | TMOD1 | 7111 | RNAseq | -1.0074 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TMOD1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TMOD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMOD1 | 7111 | 7 | 8 | 15 | |
| GSE20123 | TMOD1 | 7111 | 7 | 7 | 16 | |
| GSE43470 | TMOD1 | 7111 | 6 | 3 | 34 | |
| GSE46452 | TMOD1 | 7111 | 6 | 14 | 39 | |
| GSE47630 | TMOD1 | 7111 | 1 | 17 | 22 | |
| GSE54993 | TMOD1 | 7111 | 3 | 3 | 64 | |
| GSE54994 | TMOD1 | 7111 | 8 | 11 | 34 | |
| GSE60625 | TMOD1 | 7111 | 0 | 0 | 11 | |
| GSE74703 | TMOD1 | 7111 | 5 | 3 | 28 | |
| GSE74704 | TMOD1 | 7111 | 3 | 5 | 12 | |
| TCGA | TMOD1 | 7111 | 27 | 22 | 47 |
Total number of gains: 73; Total number of losses: 93; Total Number of normals: 322.
Somatic mutations of TMOD1:
Generating mutation plots.
Highly correlated genes for TMOD1:
Showing top 20/927 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMOD1 | C1QTNF7 | 0.881673 | 3 | 0 | 3 |
| TMOD1 | ADAMTSL1 | 0.868262 | 3 | 0 | 3 |
| TMOD1 | FILIP1 | 0.868066 | 3 | 0 | 3 |
| TMOD1 | CYS1 | 0.863718 | 4 | 0 | 4 |
| TMOD1 | PTCHD1 | 0.830781 | 3 | 0 | 3 |
| TMOD1 | PLEKHB1 | 0.822679 | 5 | 0 | 5 |
| TMOD1 | MYOC | 0.822167 | 7 | 0 | 7 |
| TMOD1 | PPP1R14A | 0.821416 | 3 | 0 | 3 |
| TMOD1 | ITGB1BP2 | 0.813207 | 5 | 0 | 5 |
| TMOD1 | RGS7BP | 0.811334 | 3 | 0 | 3 |
| TMOD1 | CFL2 | 0.804615 | 3 | 0 | 3 |
| TMOD1 | OGN | 0.800197 | 7 | 0 | 7 |
| TMOD1 | UBXN10 | 0.799395 | 3 | 0 | 3 |
| TMOD1 | PGR | 0.796158 | 4 | 0 | 4 |
| TMOD1 | MAMDC2 | 0.794038 | 4 | 0 | 4 |
| TMOD1 | KLHL15 | 0.789667 | 3 | 0 | 3 |
| TMOD1 | VIT | 0.786675 | 3 | 0 | 3 |
| TMOD1 | CASQ2 | 0.786156 | 8 | 0 | 7 |
| TMOD1 | RBPMS2 | 0.782211 | 5 | 0 | 5 |
| TMOD1 | RNF14 | 0.780983 | 3 | 0 | 3 |
For details and further investigation, click here
