| Full name: dynein axonemal heavy chain 14 | Alias Symbol: Dnahc14|HL-18|HL18|DKFZp781B1548|MGC27277 | ||
| Type: protein-coding gene | Cytoband: 1q42.12 | ||
| Entrez ID: 127602 | HGNC ID: HGNC:2945 | Ensembl Gene: ENSG00000185842 | OMIM ID: 603341 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAH14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAH14 | 127602 | 242283_at | 1.6078 | 0.0124 | |
| GSE26886 | DNAH14 | 127602 | 242283_at | 0.6513 | 0.0519 | |
| GSE45670 | DNAH14 | 127602 | 242283_at | 1.2716 | 0.0044 | |
| GSE53622 | DNAH14 | 127602 | 22349 | 0.9080 | 0.0001 | |
| GSE53624 | DNAH14 | 127602 | 7740 | 1.5897 | 0.0000 | |
| GSE63941 | DNAH14 | 127602 | 242283_at | 1.9925 | 0.0634 | |
| GSE77861 | DNAH14 | 127602 | 242283_at | 0.3955 | 0.0028 | |
| GSE97050 | DNAH14 | 127602 | A_32_P87531 | 0.0221 | 0.9599 | |
| SRP007169 | DNAH14 | 127602 | RNAseq | 1.1679 | 0.1752 | |
| SRP008496 | DNAH14 | 127602 | RNAseq | 1.5603 | 0.0051 | |
| SRP064894 | DNAH14 | 127602 | RNAseq | 1.4548 | 0.0000 | |
| SRP133303 | DNAH14 | 127602 | RNAseq | 1.3895 | 0.0001 | |
| SRP159526 | DNAH14 | 127602 | RNAseq | 2.8850 | 0.0000 | |
| SRP193095 | DNAH14 | 127602 | RNAseq | 1.2290 | 0.0000 | |
| SRP219564 | DNAH14 | 127602 | RNAseq | 1.9323 | 0.0029 | |
| TCGA | DNAH14 | 127602 | RNAseq | 0.3766 | 0.1721 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by DNAH14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAH14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAH14 | 127602 | 11 | 0 | 19 | |
| GSE20123 | DNAH14 | 127602 | 11 | 0 | 19 | |
| GSE43470 | DNAH14 | 127602 | 7 | 1 | 35 | |
| GSE46452 | DNAH14 | 127602 | 3 | 1 | 55 | |
| GSE47630 | DNAH14 | 127602 | 15 | 0 | 25 | |
| GSE54993 | DNAH14 | 127602 | 0 | 6 | 64 | |
| GSE54994 | DNAH14 | 127602 | 16 | 0 | 37 | |
| GSE60625 | DNAH14 | 127602 | 0 | 0 | 11 | |
| GSE74703 | DNAH14 | 127602 | 7 | 1 | 28 | |
| GSE74704 | DNAH14 | 127602 | 5 | 0 | 15 | |
| TCGA | DNAH14 | 127602 | 45 | 5 | 46 |
Total number of gains: 120; Total number of losses: 14; Total Number of normals: 354.
Somatic mutations of DNAH14:
Generating mutation plots.
Highly correlated genes for DNAH14:
Showing top 20/1476 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAH14 | HELZ | 0.805393 | 3 | 0 | 3 |
| DNAH14 | CXXC1 | 0.803688 | 3 | 0 | 3 |
| DNAH14 | NUFIP2 | 0.803622 | 3 | 0 | 3 |
| DNAH14 | THUMPD2 | 0.79903 | 3 | 0 | 3 |
| DNAH14 | FYN | 0.795064 | 3 | 0 | 3 |
| DNAH14 | CIAO1 | 0.792976 | 3 | 0 | 3 |
| DNAH14 | TMTC1 | 0.78548 | 3 | 0 | 3 |
| DNAH14 | ZHX2 | 0.783394 | 3 | 0 | 3 |
| DNAH14 | POLR2K | 0.778959 | 3 | 0 | 3 |
| DNAH14 | SS18L1 | 0.762754 | 3 | 0 | 3 |
| DNAH14 | TUBA1B | 0.761846 | 4 | 0 | 4 |
| DNAH14 | AKT1 | 0.759322 | 4 | 0 | 4 |
| DNAH14 | NEK3 | 0.755211 | 3 | 0 | 3 |
| DNAH14 | FLVCR1 | 0.749436 | 6 | 0 | 6 |
| DNAH14 | TOR1A | 0.749166 | 3 | 0 | 3 |
| DNAH14 | CPSF7 | 0.748315 | 4 | 0 | 3 |
| DNAH14 | CCT5 | 0.747181 | 4 | 0 | 4 |
| DNAH14 | AIMP2 | 0.745229 | 4 | 0 | 4 |
| DNAH14 | TRIP13 | 0.743539 | 4 | 0 | 4 |
| DNAH14 | MZT1 | 0.742138 | 4 | 0 | 4 |
For details and further investigation, click here
