| Full name: drebrin 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 1627 | HGNC ID: HGNC:2695 | Ensembl Gene: ENSG00000113758 | OMIM ID: 126660 |
| Drug and gene relationship at DGIdb | |||
Expression of DBN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DBN1 | 1627 | 202806_at | 0.3448 | 0.3770 | |
| GSE20347 | DBN1 | 1627 | 202806_at | 0.3046 | 0.1102 | |
| GSE23400 | DBN1 | 1627 | 202806_at | 0.1850 | 0.0252 | |
| GSE26886 | DBN1 | 1627 | 202806_at | 1.6364 | 0.0000 | |
| GSE29001 | DBN1 | 1627 | 202806_at | 0.4098 | 0.1878 | |
| GSE38129 | DBN1 | 1627 | 202806_at | 0.1347 | 0.5231 | |
| GSE45670 | DBN1 | 1627 | 202806_at | -0.1339 | 0.6698 | |
| GSE53622 | DBN1 | 1627 | 29615 | 0.1361 | 0.2108 | |
| GSE53624 | DBN1 | 1627 | 29615 | 0.4201 | 0.0000 | |
| GSE63941 | DBN1 | 1627 | 202806_at | -1.5562 | 0.0591 | |
| GSE77861 | DBN1 | 1627 | 217025_s_at | -0.1021 | 0.7166 | |
| GSE97050 | DBN1 | 1627 | A_23_P156284 | -0.2073 | 0.5313 | |
| SRP007169 | DBN1 | 1627 | RNAseq | 0.5029 | 0.2134 | |
| SRP008496 | DBN1 | 1627 | RNAseq | 0.6099 | 0.0472 | |
| SRP064894 | DBN1 | 1627 | RNAseq | 0.7741 | 0.0015 | |
| SRP133303 | DBN1 | 1627 | RNAseq | 0.2781 | 0.1828 | |
| SRP159526 | DBN1 | 1627 | RNAseq | 0.7966 | 0.0206 | |
| SRP193095 | DBN1 | 1627 | RNAseq | 0.8553 | 0.0000 | |
| SRP219564 | DBN1 | 1627 | RNAseq | 0.3678 | 0.5465 | |
| TCGA | DBN1 | 1627 | RNAseq | -0.0572 | 0.3777 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DBN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DBN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DBN1 | 1627 | 2 | 13 | 15 | |
| GSE20123 | DBN1 | 1627 | 2 | 13 | 15 | |
| GSE43470 | DBN1 | 1627 | 1 | 11 | 31 | |
| GSE46452 | DBN1 | 1627 | 0 | 27 | 32 | |
| GSE47630 | DBN1 | 1627 | 1 | 20 | 19 | |
| GSE54993 | DBN1 | 1627 | 10 | 2 | 58 | |
| GSE54994 | DBN1 | 1627 | 2 | 17 | 34 | |
| GSE60625 | DBN1 | 1627 | 1 | 0 | 10 | |
| GSE74703 | DBN1 | 1627 | 1 | 7 | 28 | |
| GSE74704 | DBN1 | 1627 | 1 | 6 | 13 | |
| TCGA | DBN1 | 1627 | 8 | 34 | 54 |
Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.
Somatic mutations of DBN1:
Generating mutation plots.
Highly correlated genes for DBN1:
Showing top 20/583 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DBN1 | U2SURP | 0.809593 | 3 | 0 | 3 |
| DBN1 | PET117 | 0.806234 | 3 | 0 | 3 |
| DBN1 | THBD | 0.772737 | 3 | 0 | 3 |
| DBN1 | TP53I13 | 0.7659 | 3 | 0 | 3 |
| DBN1 | DGKH | 0.765423 | 3 | 0 | 3 |
| DBN1 | ALKBH6 | 0.764594 | 3 | 0 | 3 |
| DBN1 | CHCHD6 | 0.756984 | 3 | 0 | 3 |
| DBN1 | CCM2 | 0.756161 | 3 | 0 | 3 |
| DBN1 | CSNK1G2 | 0.751643 | 4 | 0 | 4 |
| DBN1 | DDX19A | 0.747295 | 3 | 0 | 3 |
| DBN1 | BRAT1 | 0.747051 | 3 | 0 | 3 |
| DBN1 | LRP5L | 0.745324 | 4 | 0 | 4 |
| DBN1 | TMEM161A | 0.732709 | 3 | 0 | 3 |
| DBN1 | TBC1D25 | 0.727746 | 3 | 0 | 3 |
| DBN1 | KDM6B | 0.726921 | 3 | 0 | 3 |
| DBN1 | GGNBP2 | 0.726746 | 3 | 0 | 3 |
| DBN1 | ELFN1 | 0.720908 | 4 | 0 | 3 |
| DBN1 | SLC25A42 | 0.720832 | 3 | 0 | 3 |
| DBN1 | EMD | 0.71766 | 4 | 0 | 4 |
| DBN1 | PPP1R16A | 0.717477 | 3 | 0 | 3 |
For details and further investigation, click here
