| Full name: FAM20C golgi associated secretory pathway kinase | Alias Symbol: IMAGE:4942737|DKFZp547D065|DMP4|G-CK | ||
| Type: protein-coding gene | Cytoband: 7p22.3 | ||
| Entrez ID: 56975 | HGNC ID: HGNC:22140 | Ensembl Gene: ENSG00000177706 | OMIM ID: 611061 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM20C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM20C | 56975 | 226722_at | 0.8196 | 0.2289 | |
| GSE26886 | FAM20C | 56975 | 229438_at | 0.0043 | 0.9767 | |
| GSE45670 | FAM20C | 56975 | 226722_at | 0.2644 | 0.4719 | |
| GSE53622 | FAM20C | 56975 | 121698 | 0.6345 | 0.0000 | |
| GSE53624 | FAM20C | 56975 | 121698 | 0.8961 | 0.0000 | |
| GSE63941 | FAM20C | 56975 | 226722_at | -4.0163 | 0.0002 | |
| GSE77861 | FAM20C | 56975 | 226722_at | 0.6487 | 0.0197 | |
| GSE97050 | FAM20C | 56975 | A_23_P250122 | 0.2033 | 0.5909 | |
| SRP007169 | FAM20C | 56975 | RNAseq | 2.9356 | 0.0007 | |
| SRP008496 | FAM20C | 56975 | RNAseq | 2.1194 | 0.0005 | |
| SRP064894 | FAM20C | 56975 | RNAseq | 1.6772 | 0.0000 | |
| SRP133303 | FAM20C | 56975 | RNAseq | 1.3358 | 0.0000 | |
| SRP159526 | FAM20C | 56975 | RNAseq | 1.4273 | 0.0002 | |
| SRP193095 | FAM20C | 56975 | RNAseq | 1.2711 | 0.0000 | |
| SRP219564 | FAM20C | 56975 | RNAseq | 1.2360 | 0.0843 | |
| TCGA | FAM20C | 56975 | RNAseq | -0.1357 | 0.1060 |
Upregulated datasets: 6; Downregulated datasets: 1.
Survival by FAM20C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM20C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM20C | 56975 | 14 | 0 | 16 | |
| GSE20123 | FAM20C | 56975 | 14 | 0 | 16 | |
| GSE43470 | FAM20C | 56975 | 6 | 2 | 35 | |
| GSE46452 | FAM20C | 56975 | 13 | 1 | 45 | |
| GSE47630 | FAM20C | 56975 | 12 | 1 | 27 | |
| GSE54993 | FAM20C | 56975 | 3 | 10 | 57 | |
| GSE54994 | FAM20C | 56975 | 23 | 1 | 29 | |
| GSE60625 | FAM20C | 56975 | 0 | 0 | 11 | |
| GSE74703 | FAM20C | 56975 | 6 | 1 | 29 | |
| GSE74704 | FAM20C | 56975 | 9 | 0 | 11 | |
| TCGA | FAM20C | 56975 | 56 | 6 | 34 |
Total number of gains: 156; Total number of losses: 22; Total Number of normals: 310.
Somatic mutations of FAM20C:
Generating mutation plots.
Highly correlated genes for FAM20C:
Showing top 20/752 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM20C | CLIP3 | 0.798898 | 3 | 0 | 3 |
| FAM20C | CD200 | 0.789153 | 3 | 0 | 3 |
| FAM20C | DEGS1 | 0.779952 | 4 | 0 | 4 |
| FAM20C | C20orf194 | 0.772929 | 3 | 0 | 3 |
| FAM20C | MSTO1 | 0.769088 | 3 | 0 | 3 |
| FAM20C | DGKH | 0.766193 | 3 | 0 | 3 |
| FAM20C | FBLN5 | 0.761022 | 3 | 0 | 3 |
| FAM20C | TMTC1 | 0.759652 | 3 | 0 | 3 |
| FAM20C | NMB | 0.754803 | 3 | 0 | 3 |
| FAM20C | TP53I13 | 0.737078 | 4 | 0 | 4 |
| FAM20C | PTPN14 | 0.732464 | 3 | 0 | 3 |
| FAM20C | KDSR | 0.731813 | 3 | 0 | 3 |
| FAM20C | RRAS2 | 0.729021 | 3 | 0 | 3 |
| FAM20C | ADCY3 | 0.728822 | 3 | 0 | 3 |
| FAM20C | NTPCR | 0.726479 | 3 | 0 | 3 |
| FAM20C | ST3GAL2 | 0.724703 | 5 | 0 | 5 |
| FAM20C | HGF | 0.723695 | 3 | 0 | 3 |
| FAM20C | CCDC86 | 0.72334 | 3 | 0 | 3 |
| FAM20C | DPYSL2 | 0.72083 | 4 | 0 | 3 |
| FAM20C | CHD1 | 0.718629 | 3 | 0 | 3 |
For details and further investigation, click here
