| Full name: small nuclear ribonucleoprotein U11/U12 subunit 48 | Alias Symbol: FLJ32234|dJ512B11.2|dJ336K20B.1 | ||
| Type: protein-coding gene | Cytoband: 6p24.3 | ||
| Entrez ID: 154007 | HGNC ID: HGNC:21368 | Ensembl Gene: ENSG00000168566 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SNRNP48:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRNP48 | 154007 | 226263_at | 0.5419 | 0.0479 | |
| GSE26886 | SNRNP48 | 154007 | 226263_at | 0.3231 | 0.1134 | |
| GSE45670 | SNRNP48 | 154007 | 226263_at | 0.3484 | 0.0053 | |
| GSE53622 | SNRNP48 | 154007 | 31380 | 0.2908 | 0.0001 | |
| GSE53624 | SNRNP48 | 154007 | 21923 | -0.8780 | 0.0000 | |
| GSE63941 | SNRNP48 | 154007 | 226263_at | 0.1851 | 0.6276 | |
| GSE77861 | SNRNP48 | 154007 | 226263_at | 0.0806 | 0.6193 | |
| GSE97050 | SNRNP48 | 154007 | A_33_P3404448 | -0.0079 | 0.9830 | |
| SRP007169 | SNRNP48 | 154007 | RNAseq | 0.3320 | 0.5303 | |
| SRP008496 | SNRNP48 | 154007 | RNAseq | 0.3979 | 0.1882 | |
| SRP064894 | SNRNP48 | 154007 | RNAseq | 0.2158 | 0.3250 | |
| SRP133303 | SNRNP48 | 154007 | RNAseq | 0.4357 | 0.0014 | |
| SRP159526 | SNRNP48 | 154007 | RNAseq | 0.7286 | 0.0322 | |
| SRP193095 | SNRNP48 | 154007 | RNAseq | 0.1378 | 0.0535 | |
| SRP219564 | SNRNP48 | 154007 | RNAseq | -0.2449 | 0.3742 | |
| TCGA | SNRNP48 | 154007 | RNAseq | 0.0410 | 0.4734 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNRNP48 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNRNP48:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRNP48 | 154007 | 4 | 5 | 21 | |
| GSE20123 | SNRNP48 | 154007 | 3 | 5 | 22 | |
| GSE43470 | SNRNP48 | 154007 | 8 | 2 | 33 | |
| GSE46452 | SNRNP48 | 154007 | 1 | 10 | 48 | |
| GSE47630 | SNRNP48 | 154007 | 7 | 8 | 25 | |
| GSE54993 | SNRNP48 | 154007 | 1 | 1 | 68 | |
| GSE54994 | SNRNP48 | 154007 | 10 | 3 | 40 | |
| GSE60625 | SNRNP48 | 154007 | 0 | 1 | 10 | |
| GSE74703 | SNRNP48 | 154007 | 7 | 2 | 27 | |
| GSE74704 | SNRNP48 | 154007 | 2 | 2 | 16 | |
| TCGA | SNRNP48 | 154007 | 15 | 29 | 52 |
Total number of gains: 58; Total number of losses: 68; Total Number of normals: 362.
Somatic mutations of SNRNP48:
Generating mutation plots.
Highly correlated genes for SNRNP48:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRNP48 | DGKH | 0.769128 | 3 | 0 | 3 |
| SNRNP48 | TNPO1 | 0.75495 | 3 | 0 | 3 |
| SNRNP48 | WDR43 | 0.752109 | 3 | 0 | 3 |
| SNRNP48 | ZNF778 | 0.75134 | 3 | 0 | 3 |
| SNRNP48 | ASPH | 0.741607 | 3 | 0 | 3 |
| SNRNP48 | YTHDF3 | 0.731445 | 3 | 0 | 3 |
| SNRNP48 | RBM15 | 0.727471 | 3 | 0 | 3 |
| SNRNP48 | NCAPG | 0.709248 | 4 | 0 | 3 |
| SNRNP48 | THUMPD2 | 0.703048 | 3 | 0 | 3 |
| SNRNP48 | TAF4B | 0.698924 | 3 | 0 | 3 |
| SNRNP48 | METAP1D | 0.69626 | 3 | 0 | 3 |
| SNRNP48 | SRRD | 0.681095 | 4 | 0 | 3 |
| SNRNP48 | CEBPZ | 0.679403 | 4 | 0 | 3 |
| SNRNP48 | ZC3HAV1 | 0.677224 | 3 | 0 | 3 |
| SNRNP48 | PSMA2 | 0.677033 | 3 | 0 | 3 |
| SNRNP48 | BMP7 | 0.676589 | 3 | 0 | 3 |
| SNRNP48 | CCT6A | 0.670173 | 4 | 0 | 3 |
| SNRNP48 | RPS21 | 0.664285 | 4 | 0 | 3 |
| SNRNP48 | TMF1 | 0.658883 | 4 | 0 | 4 |
| SNRNP48 | MORC2 | 0.656845 | 4 | 0 | 3 |
For details and further investigation, click here
