| Full name: ubiquitin B | Alias Symbol: MGC8385|FLJ25987 | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 7314 | HGNC ID: HGNC:12463 | Ensembl Gene: ENSG00000170315 | OMIM ID: 191339 |
| Drug and gene relationship at DGIdb | |||
Expression of UBB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBB | 7314 | 200633_at | 0.0514 | 0.8716 | |
| GSE20347 | UBB | 7314 | 200633_at | 0.2990 | 0.0071 | |
| GSE23400 | UBB | 7314 | 200633_at | 0.2104 | 0.0027 | |
| GSE26886 | UBB | 7314 | 200633_at | 0.5144 | 0.0000 | |
| GSE29001 | UBB | 7314 | 200633_at | 0.2255 | 0.0642 | |
| GSE38129 | UBB | 7314 | 200633_at | 0.1626 | 0.1103 | |
| GSE45670 | UBB | 7314 | 200633_at | 0.1547 | 0.2546 | |
| GSE53622 | UBB | 7314 | 173158 | 0.2400 | 0.0137 | |
| GSE53624 | UBB | 7314 | 173158 | 0.1008 | 0.1330 | |
| GSE63941 | UBB | 7314 | 200633_at | -0.6078 | 0.7340 | |
| GSE77861 | UBB | 7314 | 200633_at | 0.2446 | 0.0609 | |
| GSE97050 | UBB | 7314 | A_23_P27215 | 0.3118 | 0.2296 | |
| SRP007169 | UBB | 7314 | RNAseq | 0.1834 | 0.6965 | |
| SRP008496 | UBB | 7314 | RNAseq | 0.4614 | 0.2500 | |
| SRP064894 | UBB | 7314 | RNAseq | 0.5269 | 0.0275 | |
| SRP133303 | UBB | 7314 | RNAseq | 0.3240 | 0.0085 | |
| SRP159526 | UBB | 7314 | RNAseq | 0.5768 | 0.0001 | |
| SRP193095 | UBB | 7314 | RNAseq | -0.1285 | 0.4168 | |
| SRP219564 | UBB | 7314 | RNAseq | -0.0641 | 0.8848 | |
| TCGA | UBB | 7314 | RNAseq | -0.0609 | 0.2543 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBB | 7314 | 3 | 3 | 24 | |
| GSE20123 | UBB | 7314 | 3 | 4 | 23 | |
| GSE43470 | UBB | 7314 | 2 | 5 | 36 | |
| GSE46452 | UBB | 7314 | 34 | 1 | 24 | |
| GSE47630 | UBB | 7314 | 7 | 1 | 32 | |
| GSE54993 | UBB | 7314 | 3 | 3 | 64 | |
| GSE54994 | UBB | 7314 | 6 | 5 | 42 | |
| GSE60625 | UBB | 7314 | 4 | 0 | 7 | |
| GSE74703 | UBB | 7314 | 2 | 2 | 32 | |
| GSE74704 | UBB | 7314 | 2 | 1 | 17 | |
| TCGA | UBB | 7314 | 18 | 23 | 55 |
Total number of gains: 84; Total number of losses: 48; Total Number of normals: 356.
Somatic mutations of UBB:
Generating mutation plots.
Highly correlated genes for UBB:
Showing top 20/1485 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBB | DGKH | 0.80747 | 3 | 0 | 3 |
| UBB | CTBP2 | 0.776943 | 3 | 0 | 3 |
| UBB | AGRN | 0.776815 | 3 | 0 | 3 |
| UBB | C7orf50 | 0.775698 | 3 | 0 | 3 |
| UBB | UBTD2 | 0.774419 | 3 | 0 | 3 |
| UBB | INPP5B | 0.770508 | 3 | 0 | 3 |
| UBB | HSD11B1 | 0.758203 | 3 | 0 | 3 |
| UBB | RILPL1 | 0.755708 | 3 | 0 | 3 |
| UBB | BRAT1 | 0.754143 | 3 | 0 | 3 |
| UBB | C11orf49 | 0.753459 | 3 | 0 | 3 |
| UBB | CENPV | 0.75093 | 4 | 0 | 4 |
| UBB | DROSHA | 0.749018 | 3 | 0 | 3 |
| UBB | SP4 | 0.748012 | 4 | 0 | 4 |
| UBB | PTTG1IP | 0.74764 | 3 | 0 | 3 |
| UBB | TNRC18 | 0.743181 | 3 | 0 | 3 |
| UBB | BOD1 | 0.742436 | 4 | 0 | 4 |
| UBB | DEDD2 | 0.741933 | 3 | 0 | 3 |
| UBB | KIAA1324L | 0.741105 | 5 | 0 | 5 |
| UBB | KRTCAP2 | 0.741091 | 3 | 0 | 3 |
| UBB | STARD3NL | 0.740696 | 4 | 0 | 3 |
For details and further investigation, click here
