| Full name: DEAH-box helicase 16 | Alias Symbol: DBP2|Prp2|PRPF2 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 8449 | HGNC ID: HGNC:2739 | Ensembl Gene: ENSG00000204560 | OMIM ID: 603405 |
| Drug and gene relationship at DGIdb | |||
Expression of DHX16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX16 | 8449 | 203694_s_at | 0.3304 | 0.2798 | |
| GSE20347 | DHX16 | 8449 | 203694_s_at | 0.2709 | 0.0039 | |
| GSE23400 | DHX16 | 8449 | 203694_s_at | 0.4041 | 0.0000 | |
| GSE26886 | DHX16 | 8449 | 203694_s_at | 0.1407 | 0.3223 | |
| GSE29001 | DHX16 | 8449 | 203694_s_at | 0.2070 | 0.1934 | |
| GSE38129 | DHX16 | 8449 | 203694_s_at | 0.3549 | 0.0000 | |
| GSE45670 | DHX16 | 8449 | 203694_s_at | 0.2662 | 0.0296 | |
| GSE53622 | DHX16 | 8449 | 136398 | 0.4303 | 0.0000 | |
| GSE53624 | DHX16 | 8449 | 136398 | 0.5004 | 0.0000 | |
| GSE63941 | DHX16 | 8449 | 203694_s_at | 0.3148 | 0.2662 | |
| GSE77861 | DHX16 | 8449 | 203694_s_at | 0.2629 | 0.2921 | |
| GSE97050 | DHX16 | 8449 | A_23_P168062 | 0.4084 | 0.2536 | |
| SRP007169 | DHX16 | 8449 | RNAseq | 0.8175 | 0.0688 | |
| SRP008496 | DHX16 | 8449 | RNAseq | 0.8126 | 0.0067 | |
| SRP064894 | DHX16 | 8449 | RNAseq | 0.5344 | 0.0003 | |
| SRP133303 | DHX16 | 8449 | RNAseq | 0.1811 | 0.0881 | |
| SRP159526 | DHX16 | 8449 | RNAseq | 0.3576 | 0.0153 | |
| SRP193095 | DHX16 | 8449 | RNAseq | 0.3398 | 0.0000 | |
| SRP219564 | DHX16 | 8449 | RNAseq | 0.0592 | 0.7141 | |
| TCGA | DHX16 | 8449 | RNAseq | 0.0618 | 0.2090 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DHX16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX16 | 8449 | 5 | 1 | 24 | |
| GSE20123 | DHX16 | 8449 | 5 | 1 | 24 | |
| GSE43470 | DHX16 | 8449 | 5 | 1 | 37 | |
| GSE46452 | DHX16 | 8449 | 1 | 10 | 48 | |
| GSE47630 | DHX16 | 8449 | 7 | 3 | 30 | |
| GSE54993 | DHX16 | 8449 | 2 | 1 | 67 | |
| GSE54994 | DHX16 | 8449 | 11 | 4 | 38 | |
| GSE60625 | DHX16 | 8449 | 0 | 1 | 10 | |
| GSE74703 | DHX16 | 8449 | 5 | 0 | 31 | |
| GSE74704 | DHX16 | 8449 | 2 | 0 | 18 | |
| TCGA | DHX16 | 8449 | 18 | 16 | 62 |
Total number of gains: 61; Total number of losses: 38; Total Number of normals: 389.
Somatic mutations of DHX16:
Generating mutation plots.
Highly correlated genes for DHX16:
Showing top 20/1241 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX16 | MTCH1 | 0.727489 | 10 | 0 | 10 |
| DHX16 | ABCF1 | 0.699978 | 13 | 0 | 12 |
| DHX16 | SNRPC | 0.688869 | 11 | 0 | 9 |
| DHX16 | PUS3 | 0.687483 | 3 | 0 | 3 |
| DHX16 | CCDC167 | 0.687 | 5 | 0 | 5 |
| DHX16 | SCNM1 | 0.686056 | 3 | 0 | 3 |
| DHX16 | SLC35B2 | 0.684453 | 3 | 0 | 3 |
| DHX16 | NONO | 0.676665 | 9 | 0 | 9 |
| DHX16 | NRM | 0.676464 | 7 | 0 | 6 |
| DHX16 | EHMT2 | 0.674143 | 8 | 0 | 6 |
| DHX16 | PRR11 | 0.672687 | 3 | 0 | 3 |
| DHX16 | EBNA1BP2 | 0.672685 | 3 | 0 | 3 |
| DHX16 | KDM1A | 0.672162 | 11 | 0 | 11 |
| DHX16 | PYCR2 | 0.671106 | 3 | 0 | 3 |
| DHX16 | TOP3B | 0.669236 | 4 | 0 | 4 |
| DHX16 | GTF2H4 | 0.668672 | 10 | 0 | 9 |
| DHX16 | ZNRD1 | 0.666459 | 5 | 0 | 4 |
| DHX16 | RNF152 | 0.661523 | 3 | 0 | 3 |
| DHX16 | CMTR1 | 0.660427 | 9 | 0 | 8 |
| DHX16 | C4orf46 | 0.652649 | 3 | 0 | 3 |
For details and further investigation, click here
