| Full name: chromosome 4 open reading frame 46 | Alias Symbol: LOC201725|RCDG1 | ||
| Type: protein-coding gene | Cytoband: 4q32.1 | ||
| Entrez ID: 201725 | HGNC ID: HGNC:27320 | Ensembl Gene: ENSG00000205208 | OMIM ID: 616210 |
| Drug and gene relationship at DGIdb | |||
Expression of C4orf46:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C4orf46 | 201725 | 235088_at | 1.3921 | 0.0140 | |
| GSE26886 | C4orf46 | 201725 | 238015_at | 0.4880 | 0.1100 | |
| GSE45670 | C4orf46 | 201725 | 235088_at | 1.0344 | 0.0000 | |
| GSE53622 | C4orf46 | 201725 | 74145 | 0.8420 | 0.0000 | |
| GSE53624 | C4orf46 | 201725 | 74145 | 0.8366 | 0.0000 | |
| GSE63941 | C4orf46 | 201725 | 235088_at | 0.3729 | 0.5082 | |
| GSE77861 | C4orf46 | 201725 | 238015_at | 0.1479 | 0.4242 | |
| GSE97050 | C4orf46 | 201725 | A_33_P3377691 | 0.6212 | 0.1399 | |
| SRP007169 | C4orf46 | 201725 | RNAseq | 2.3998 | 0.0009 | |
| SRP008496 | C4orf46 | 201725 | RNAseq | 2.8150 | 0.0001 | |
| SRP064894 | C4orf46 | 201725 | RNAseq | 0.8389 | 0.0000 | |
| SRP133303 | C4orf46 | 201725 | RNAseq | 1.2415 | 0.0000 | |
| SRP159526 | C4orf46 | 201725 | RNAseq | 0.9219 | 0.0222 | |
| SRP193095 | C4orf46 | 201725 | RNAseq | 0.5686 | 0.0000 | |
| SRP219564 | C4orf46 | 201725 | RNAseq | 0.5583 | 0.1183 | |
| TCGA | C4orf46 | 201725 | RNAseq | 0.4806 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by C4orf46 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C4orf46:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C4orf46 | 201725 | 0 | 13 | 17 | |
| GSE20123 | C4orf46 | 201725 | 0 | 13 | 17 | |
| GSE43470 | C4orf46 | 201725 | 0 | 14 | 29 | |
| GSE46452 | C4orf46 | 201725 | 1 | 36 | 22 | |
| GSE47630 | C4orf46 | 201725 | 0 | 23 | 17 | |
| GSE54993 | C4orf46 | 201725 | 10 | 0 | 60 | |
| GSE54994 | C4orf46 | 201725 | 1 | 12 | 40 | |
| GSE60625 | C4orf46 | 201725 | 0 | 1 | 10 | |
| GSE74703 | C4orf46 | 201725 | 0 | 12 | 24 | |
| GSE74704 | C4orf46 | 201725 | 0 | 6 | 14 | |
| TCGA | C4orf46 | 201725 | 12 | 35 | 49 |
Total number of gains: 24; Total number of losses: 165; Total Number of normals: 299.
Somatic mutations of C4orf46:
Generating mutation plots.
Highly correlated genes for C4orf46:
Showing top 20/677 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C4orf46 | WRAP73 | 0.76288 | 3 | 0 | 3 |
| C4orf46 | BAX | 0.759275 | 3 | 0 | 3 |
| C4orf46 | PLA2G15 | 0.74487 | 3 | 0 | 3 |
| C4orf46 | SNRPC | 0.729091 | 4 | 0 | 4 |
| C4orf46 | MEX3D | 0.723219 | 3 | 0 | 3 |
| C4orf46 | POLR1A | 0.721153 | 3 | 0 | 3 |
| C4orf46 | KDM1A | 0.717184 | 4 | 0 | 4 |
| C4orf46 | FEN1 | 0.714504 | 5 | 0 | 5 |
| C4orf46 | GANAB | 0.705918 | 4 | 0 | 3 |
| C4orf46 | RASL11B | 0.705217 | 3 | 0 | 3 |
| C4orf46 | TAPBP | 0.704308 | 3 | 0 | 3 |
| C4orf46 | ZFP69B | 0.696937 | 4 | 0 | 4 |
| C4orf46 | SH2D2A | 0.696092 | 4 | 0 | 4 |
| C4orf46 | PUS1 | 0.694289 | 3 | 0 | 3 |
| C4orf46 | HMGB3 | 0.692421 | 5 | 0 | 5 |
| C4orf46 | JPH1 | 0.686457 | 3 | 0 | 3 |
| C4orf46 | FLAD1 | 0.685284 | 3 | 0 | 3 |
| C4orf46 | XRN2 | 0.683421 | 3 | 0 | 3 |
| C4orf46 | MTERF3 | 0.682986 | 4 | 0 | 3 |
| C4orf46 | NRM | 0.681365 | 4 | 0 | 3 |
For details and further investigation, click here
