ABCF1

 

Full name: ATP binding cassette subfamily F member 1 Alias Symbol: EST123147
Type: protein-coding gene Cytoband: 6p21.33
Entrez ID: 23 HGNC ID: HGNC:70 Ensembl Gene: ENSG00000204574 OMIM ID: 603429
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ABCF1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ABCF1 23 200045_at 0.5985 0.1299
GSE20347 ABCF1 23 200045_at 0.3686 0.0024
GSE23400 ABCF1 23 200045_at 0.4394 0.0000
GSE26886 ABCF1 23 200045_at -0.1095 0.5901
GSE29001 ABCF1 23 200045_at 0.2602 0.2885
GSE38129 ABCF1 23 200045_at 0.4441 0.0001
GSE45670 ABCF1 23 200045_at 0.5273 0.0004
GSE53622 ABCF1 23 153154 0.5842 0.0000
GSE53624 ABCF1 23 153154 0.7515 0.0000
GSE63941 ABCF1 23 200045_at 0.4435 0.3729
GSE77861 ABCF1 23 200045_at 0.3746 0.1482
GSE97050 ABCF1 23 A_23_P251660 0.3874 0.2464
SRP007169 ABCF1 23 RNAseq 1.1107 0.0042
SRP008496 ABCF1 23 RNAseq 1.1869 0.0000
SRP064894 ABCF1 23 RNAseq 0.5773 0.0002
SRP133303 ABCF1 23 RNAseq 0.4634 0.0004
SRP159526 ABCF1 23 RNAseq 0.4779 0.0080
SRP193095 ABCF1 23 RNAseq 0.4149 0.0001
SRP219564 ABCF1 23 RNAseq 0.4358 0.1191
TCGA ABCF1 23 RNAseq 0.0493 0.2613

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by ABCF1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ABCF1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABCF1 23 5 1 24
GSE20123 ABCF1 23 5 1 24
GSE43470 ABCF1 23 5 1 37
GSE46452 ABCF1 23 1 10 48
GSE47630 ABCF1 23 7 3 30
GSE54993 ABCF1 23 2 1 67
GSE54994 ABCF1 23 11 4 38
GSE60625 ABCF1 23 0 1 10
GSE74703 ABCF1 23 5 0 31
GSE74704 ABCF1 23 2 0 18
TCGA ABCF1 23 18 16 62

Total number of gains: 61; Total number of losses: 38; Total Number of normals: 389.  


 

Somatic mutations of ABCF1:

 

Generating mutation plots.

 

Highly correlated genes for ABCF1:

 

Showing top 20/1910 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABCF1SNRPC0.79727810010
ABCF1SMARCAD10.796333303
ABCF1SLC39A30.796103303
ABCF1SPSB20.794553303
ABCF1SLC35B20.77931303
ABCF1TAF1C0.775075303
ABCF1RBM15B0.774879303
ABCF1EXOC60.772023303
ABCF1PRR140.77125404
ABCF1SSBP40.76302303
ABCF1SRPK10.762094303
ABCF1MMS22L0.76163303
ABCF1MRPS120.758735808
ABCF1RRP360.758118606
ABCF1PDRG10.756573404
ABCF1MAGOH0.754709303
ABCF1UCK20.74535303
ABCF1MAD2L20.744893505
ABCF1FAM89A0.743041303
ABCF1UQCC20.742385303

For details and further investigation, click here