| Full name: small nuclear ribonucleoprotein polypeptide C | Alias Symbol: U1-C|Yhc1 | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 6631 | HGNC ID: HGNC:11157 | Ensembl Gene: ENSG00000124562 | OMIM ID: 603522 |
| Drug and gene relationship at DGIdb | |||
Expression of SNRPC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRPC | 6631 | 201342_at | 0.7258 | 0.0505 | |
| GSE20347 | SNRPC | 6631 | 201342_at | 0.5315 | 0.0000 | |
| GSE23400 | SNRPC | 6631 | 201342_at | 0.4758 | 0.0000 | |
| GSE26886 | SNRPC | 6631 | 201342_at | 0.8250 | 0.0000 | |
| GSE29001 | SNRPC | 6631 | 201342_at | 0.4492 | 0.0657 | |
| GSE38129 | SNRPC | 6631 | 201342_at | 0.6619 | 0.0000 | |
| GSE45670 | SNRPC | 6631 | 201342_at | 0.4196 | 0.0018 | |
| GSE53622 | SNRPC | 6631 | 22659 | 0.5607 | 0.0000 | |
| GSE53624 | SNRPC | 6631 | 22659 | 0.9158 | 0.0000 | |
| GSE63941 | SNRPC | 6631 | 201342_at | 0.6219 | 0.0336 | |
| GSE77861 | SNRPC | 6631 | 201342_at | 0.1956 | 0.2445 | |
| GSE97050 | SNRPC | 6631 | A_24_P83922 | 0.7224 | 0.1581 | |
| SRP007169 | SNRPC | 6631 | RNAseq | 0.3283 | 0.2868 | |
| SRP008496 | SNRPC | 6631 | RNAseq | 0.1753 | 0.3491 | |
| SRP064894 | SNRPC | 6631 | RNAseq | 0.9020 | 0.0014 | |
| SRP133303 | SNRPC | 6631 | RNAseq | 0.6657 | 0.0000 | |
| SRP159526 | SNRPC | 6631 | RNAseq | 0.5417 | 0.0000 | |
| SRP193095 | SNRPC | 6631 | RNAseq | 0.3804 | 0.0015 | |
| SRP219564 | SNRPC | 6631 | RNAseq | 0.5968 | 0.0714 | |
| TCGA | SNRPC | 6631 | RNAseq | 0.2932 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNRPC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNRPC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRPC | 6631 | 5 | 0 | 25 | |
| GSE20123 | SNRPC | 6631 | 5 | 0 | 25 | |
| GSE43470 | SNRPC | 6631 | 5 | 1 | 37 | |
| GSE46452 | SNRPC | 6631 | 2 | 9 | 48 | |
| GSE47630 | SNRPC | 6631 | 8 | 4 | 28 | |
| GSE54993 | SNRPC | 6631 | 3 | 1 | 66 | |
| GSE54994 | SNRPC | 6631 | 11 | 4 | 38 | |
| GSE60625 | SNRPC | 6631 | 1 | 0 | 10 | |
| GSE74703 | SNRPC | 6631 | 5 | 0 | 31 | |
| GSE74704 | SNRPC | 6631 | 2 | 0 | 18 | |
| TCGA | SNRPC | 6631 | 17 | 16 | 63 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of SNRPC:
Generating mutation plots.
Highly correlated genes for SNRPC:
Showing top 20/1936 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRPC | ABCF1 | 0.797278 | 10 | 0 | 10 |
| SNRPC | FCHO1 | 0.792819 | 3 | 0 | 3 |
| SNRPC | MMS22L | 0.791002 | 3 | 0 | 3 |
| SNRPC | SFXN2 | 0.779418 | 3 | 0 | 3 |
| SNRPC | SLC39A3 | 0.770929 | 4 | 0 | 4 |
| SNRPC | RANBP1 | 0.761142 | 11 | 0 | 11 |
| SNRPC | BAP1 | 0.749953 | 3 | 0 | 3 |
| SNRPC | USE1 | 0.746341 | 3 | 0 | 3 |
| SNRPC | MARCKSL1 | 0.745528 | 10 | 0 | 9 |
| SNRPC | PRIM2 | 0.744068 | 11 | 0 | 11 |
| SNRPC | USP41 | 0.741132 | 3 | 0 | 3 |
| SNRPC | GMNN | 0.737831 | 13 | 0 | 13 |
| SNRPC | TRIM47 | 0.736226 | 3 | 0 | 3 |
| SNRPC | EMC1 | 0.73548 | 6 | 0 | 6 |
| SNRPC | DKC1 | 0.734884 | 3 | 0 | 3 |
| SNRPC | UMPS | 0.730831 | 10 | 0 | 10 |
| SNRPC | ILF2 | 0.730528 | 12 | 0 | 12 |
| SNRPC | LSM2 | 0.729166 | 12 | 0 | 10 |
| SNRPC | C4orf46 | 0.729091 | 4 | 0 | 4 |
| SNRPC | NRM | 0.727381 | 8 | 0 | 8 |
For details and further investigation, click here
