| Full name: sodium channel modifier 1 | Alias Symbol: MGC3180 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 79005 | HGNC ID: HGNC:23136 | Ensembl Gene: ENSG00000163156 | OMIM ID: 608095 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SCNM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SCNM1 | 79005 | 93673 | 0.3870 | 0.0000 | |
| GSE53624 | SCNM1 | 79005 | 93673 | 0.6262 | 0.0000 | |
| GSE97050 | SCNM1 | 79005 | A_23_P34968 | 0.2549 | 0.3068 | |
| SRP007169 | SCNM1 | 79005 | RNAseq | -0.4588 | 0.2047 | |
| SRP008496 | SCNM1 | 79005 | RNAseq | -0.2154 | 0.5001 | |
| SRP064894 | SCNM1 | 79005 | RNAseq | 0.6278 | 0.0290 | |
| SRP133303 | SCNM1 | 79005 | RNAseq | 0.1647 | 0.2546 | |
| SRP159526 | SCNM1 | 79005 | RNAseq | 0.6344 | 0.0540 | |
| SRP193095 | SCNM1 | 79005 | RNAseq | 0.3107 | 0.0012 | |
| SRP219564 | SCNM1 | 79005 | RNAseq | 0.4864 | 0.2073 | |
| TCGA | SCNM1 | 79005 | RNAseq | 0.3146 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCNM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCNM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCNM1 | 79005 | 14 | 0 | 16 | |
| GSE20123 | SCNM1 | 79005 | 14 | 0 | 16 | |
| GSE43470 | SCNM1 | 79005 | 6 | 1 | 36 | |
| GSE46452 | SCNM1 | 79005 | 2 | 1 | 56 | |
| GSE47630 | SCNM1 | 79005 | 14 | 0 | 26 | |
| GSE54993 | SCNM1 | 79005 | 0 | 4 | 66 | |
| GSE54994 | SCNM1 | 79005 | 15 | 0 | 38 | |
| GSE60625 | SCNM1 | 79005 | 0 | 0 | 11 | |
| GSE74703 | SCNM1 | 79005 | 6 | 1 | 29 | |
| GSE74704 | SCNM1 | 79005 | 7 | 0 | 13 | |
| TCGA | SCNM1 | 79005 | 37 | 2 | 57 |
Total number of gains: 115; Total number of losses: 9; Total Number of normals: 364.
Somatic mutations of SCNM1:
Generating mutation plots.
Highly correlated genes for SCNM1:
Showing top 20/497 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCNM1 | VPS72 | 0.797918 | 4 | 0 | 4 |
| SCNM1 | BRCA1 | 0.792878 | 3 | 0 | 3 |
| SCNM1 | MCM6 | 0.788365 | 3 | 0 | 3 |
| SCNM1 | THOC5 | 0.78711 | 3 | 0 | 3 |
| SCNM1 | ILF3 | 0.781629 | 3 | 0 | 3 |
| SCNM1 | ATIC | 0.780922 | 3 | 0 | 3 |
| SCNM1 | SENP3 | 0.779668 | 3 | 0 | 3 |
| SCNM1 | MRPL47 | 0.77822 | 3 | 0 | 3 |
| SCNM1 | SASS6 | 0.774357 | 3 | 0 | 3 |
| SCNM1 | MRPL55 | 0.773487 | 3 | 0 | 3 |
| SCNM1 | USP42 | 0.77193 | 3 | 0 | 3 |
| SCNM1 | KIF3C | 0.771292 | 3 | 0 | 3 |
| SCNM1 | XPO1 | 0.768786 | 3 | 0 | 3 |
| SCNM1 | MCM3 | 0.76493 | 3 | 0 | 3 |
| SCNM1 | SETD1A | 0.764438 | 3 | 0 | 3 |
| SCNM1 | GORAB | 0.760954 | 3 | 0 | 3 |
| SCNM1 | NVL | 0.760424 | 3 | 0 | 3 |
| SCNM1 | WDR54 | 0.760154 | 3 | 0 | 3 |
| SCNM1 | TSEN15 | 0.759961 | 3 | 0 | 3 |
| SCNM1 | NONO | 0.758851 | 3 | 0 | 3 |
For details and further investigation, click here
