| Full name: proline rich 11 | Alias Symbol: FLJ11029 | ||
| Type: protein-coding gene | Cytoband: 17q23.2 | ||
| Entrez ID: 55771 | HGNC ID: HGNC:25619 | Ensembl Gene: ENSG00000068489 | OMIM ID: 615920 |
| Drug and gene relationship at DGIdb | |||
Expression of PRR11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR11 | 55771 | 219392_x_at | 0.4327 | 0.4612 | |
| GSE20347 | PRR11 | 55771 | 219392_x_at | 0.5882 | 0.0033 | |
| GSE23400 | PRR11 | 55771 | 219392_x_at | 0.2400 | 0.0038 | |
| GSE26886 | PRR11 | 55771 | 219392_x_at | 0.4282 | 0.0341 | |
| GSE29001 | PRR11 | 55771 | 219392_x_at | 0.5408 | 0.0085 | |
| GSE38129 | PRR11 | 55771 | 219392_x_at | 0.4547 | 0.0379 | |
| GSE45670 | PRR11 | 55771 | 232215_x_at | 0.3224 | 0.0034 | |
| GSE53622 | PRR11 | 55771 | 12547 | 1.2886 | 0.0000 | |
| GSE53624 | PRR11 | 55771 | 12547 | 1.3047 | 0.0000 | |
| GSE63941 | PRR11 | 55771 | 228273_at | 1.7306 | 0.0235 | |
| GSE77861 | PRR11 | 55771 | 219392_x_at | 0.6630 | 0.0665 | |
| GSE97050 | PRR11 | 55771 | A_33_P3403075 | 1.1460 | 0.1298 | |
| SRP007169 | PRR11 | 55771 | RNAseq | 1.3569 | 0.0001 | |
| SRP008496 | PRR11 | 55771 | RNAseq | 1.0679 | 0.0007 | |
| SRP064894 | PRR11 | 55771 | RNAseq | 1.5146 | 0.0000 | |
| SRP133303 | PRR11 | 55771 | RNAseq | 1.1230 | 0.0000 | |
| SRP159526 | PRR11 | 55771 | RNAseq | 1.1728 | 0.0008 | |
| SRP193095 | PRR11 | 55771 | RNAseq | 0.6256 | 0.0000 | |
| SRP219564 | PRR11 | 55771 | RNAseq | 0.8445 | 0.1275 | |
| TCGA | PRR11 | 55771 | RNAseq | 1.3693 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by PRR11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR11 | 55771 | 6 | 1 | 23 | |
| GSE20123 | PRR11 | 55771 | 6 | 1 | 23 | |
| GSE43470 | PRR11 | 55771 | 3 | 0 | 40 | |
| GSE46452 | PRR11 | 55771 | 32 | 0 | 27 | |
| GSE47630 | PRR11 | 55771 | 7 | 1 | 32 | |
| GSE54993 | PRR11 | 55771 | 2 | 5 | 63 | |
| GSE54994 | PRR11 | 55771 | 9 | 5 | 39 | |
| GSE60625 | PRR11 | 55771 | 4 | 0 | 7 | |
| GSE74703 | PRR11 | 55771 | 3 | 0 | 33 | |
| GSE74704 | PRR11 | 55771 | 5 | 1 | 14 | |
| TCGA | PRR11 | 55771 | 26 | 7 | 63 |
Total number of gains: 103; Total number of losses: 21; Total Number of normals: 364.
Somatic mutations of PRR11:
Generating mutation plots.
Highly correlated genes for PRR11:
Showing top 20/945 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR11 | DDX59 | 0.942981 | 4 | 0 | 4 |
| PRR11 | ZNF721 | 0.933878 | 8 | 0 | 8 |
| PRR11 | ALMS1 | 0.905782 | 7 | 0 | 7 |
| PRR11 | GTSE1 | 0.845871 | 12 | 0 | 11 |
| PRR11 | FUT8-AS1 | 0.83644 | 4 | 0 | 4 |
| PRR11 | TNRC6C-AS1 | 0.830074 | 4 | 0 | 4 |
| PRR11 | ZC3H7B | 0.804124 | 7 | 0 | 6 |
| PRR11 | ANKRD10-IT1 | 0.795147 | 8 | 0 | 8 |
| PRR11 | HAUS2 | 0.786372 | 11 | 0 | 9 |
| PRR11 | WDPCP | 0.785846 | 5 | 0 | 4 |
| PRR11 | GTF2H3 | 0.762359 | 11 | 0 | 9 |
| PRR11 | SH2B2 | 0.753878 | 9 | 0 | 9 |
| PRR11 | SLC19A1 | 0.743095 | 3 | 0 | 3 |
| PRR11 | MTHFD1L | 0.733086 | 3 | 0 | 3 |
| PRR11 | UBXN2A | 0.716635 | 5 | 0 | 3 |
| PRR11 | POLR1B | 0.712583 | 9 | 0 | 6 |
| PRR11 | BIRC5 | 0.703421 | 7 | 0 | 6 |
| PRR11 | DCBLD1 | 0.699254 | 5 | 0 | 5 |
| PRR11 | HOXD11 | 0.697844 | 7 | 0 | 6 |
| PRR11 | BOP1 | 0.696833 | 3 | 0 | 3 |
For details and further investigation, click here
