| Full name: ADAM metallopeptidase domain 30 | Alias Symbol: svph4 | ||
| Type: protein-coding gene | Cytoband: 1p12 | ||
| Entrez ID: 11085 | HGNC ID: HGNC:208 | Ensembl Gene: ENSG00000134249 | OMIM ID: 604779 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAM30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAM30 | 11085 | 221446_at | 0.0026 | 0.9942 | |
| GSE20347 | ADAM30 | 11085 | 221446_at | 0.0201 | 0.8025 | |
| GSE23400 | ADAM30 | 11085 | 221446_at | -0.1934 | 0.0000 | |
| GSE26886 | ADAM30 | 11085 | 221446_at | 0.2340 | 0.0651 | |
| GSE29001 | ADAM30 | 11085 | 221446_at | -0.1925 | 0.2216 | |
| GSE38129 | ADAM30 | 11085 | 221446_at | -0.0825 | 0.3934 | |
| GSE45670 | ADAM30 | 11085 | 221446_at | -0.0834 | 0.3149 | |
| GSE53622 | ADAM30 | 11085 | 56604 | -0.0834 | 0.6257 | |
| GSE53624 | ADAM30 | 11085 | 56604 | 0.4429 | 0.0004 | |
| GSE63941 | ADAM30 | 11085 | 221446_at | 0.0955 | 0.4809 | |
| GSE77861 | ADAM30 | 11085 | 221446_at | -0.0873 | 0.4075 | |
| TCGA | ADAM30 | 11085 | RNAseq | 1.9564 | 0.4010 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADAM30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAM30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAM30 | 11085 | 3 | 5 | 22 | |
| GSE20123 | ADAM30 | 11085 | 4 | 5 | 21 | |
| GSE43470 | ADAM30 | 11085 | 1 | 3 | 39 | |
| GSE46452 | ADAM30 | 11085 | 2 | 1 | 56 | |
| GSE47630 | ADAM30 | 11085 | 11 | 3 | 26 | |
| GSE54993 | ADAM30 | 11085 | 0 | 2 | 68 | |
| GSE54994 | ADAM30 | 11085 | 12 | 0 | 41 | |
| GSE60625 | ADAM30 | 11085 | 0 | 0 | 11 | |
| GSE74703 | ADAM30 | 11085 | 1 | 3 | 32 | |
| GSE74704 | ADAM30 | 11085 | 2 | 3 | 15 | |
| TCGA | ADAM30 | 11085 | 18 | 23 | 55 |
Total number of gains: 54; Total number of losses: 48; Total Number of normals: 386.
Somatic mutations of ADAM30:
Generating mutation plots.
Highly correlated genes for ADAM30:
Showing top 20/1082 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAM30 | DLGAP3 | 0.720392 | 3 | 0 | 3 |
| ADAM30 | GUCY2D | 0.707455 | 3 | 0 | 3 |
| ADAM30 | ADRB1 | 0.702979 | 3 | 0 | 3 |
| ADAM30 | ST8SIA5 | 0.700197 | 3 | 0 | 3 |
| ADAM30 | KSR1 | 0.699417 | 4 | 0 | 4 |
| ADAM30 | BTNL3 | 0.698397 | 6 | 0 | 6 |
| ADAM30 | FNDC8 | 0.693891 | 5 | 0 | 5 |
| ADAM30 | INE1 | 0.693064 | 5 | 0 | 5 |
| ADAM30 | TEX11 | 0.690978 | 4 | 0 | 4 |
| ADAM30 | AMACR | 0.688875 | 3 | 0 | 3 |
| ADAM30 | CYLC1 | 0.688661 | 4 | 0 | 4 |
| ADAM30 | SRPK3 | 0.688651 | 3 | 0 | 3 |
| ADAM30 | SEMA6C | 0.687164 | 5 | 0 | 5 |
| ADAM30 | SERPINA2 | 0.686687 | 3 | 0 | 3 |
| ADAM30 | KIR3DL3 | 0.686505 | 4 | 0 | 4 |
| ADAM30 | KIR2DS5 | 0.685989 | 5 | 0 | 5 |
| ADAM30 | OR10H3 | 0.684476 | 4 | 0 | 4 |
| ADAM30 | TNFSF8 | 0.684031 | 4 | 0 | 3 |
| ADAM30 | SIX3-AS1 | 0.683116 | 4 | 0 | 4 |
| ADAM30 | CNIH2 | 0.682517 | 4 | 0 | 3 |
For details and further investigation, click here
