| Full name: thioesterase superfamily member 5 | Alias Symbol: FLJ37964 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 284486 | HGNC ID: HGNC:26755 | Ensembl Gene: ENSG00000196407 | OMIM ID: 615653 |
| Drug and gene relationship at DGIdb | |||
Expression of THEM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THEM5 | 284486 | 1562490_at | -0.0030 | 0.9922 | |
| GSE26886 | THEM5 | 284486 | 1562490_at | 0.1336 | 0.2193 | |
| GSE45670 | THEM5 | 284486 | 1562490_at | 0.1483 | 0.2378 | |
| GSE63941 | THEM5 | 284486 | 1562490_at | 0.0429 | 0.7602 | |
| GSE77861 | THEM5 | 284486 | 1562490_at | -0.0398 | 0.6575 | |
| GSE97050 | THEM5 | 284486 | A_33_P3270826 | 0.0143 | 0.9567 | |
| SRP133303 | THEM5 | 284486 | RNAseq | -0.9671 | 0.0136 | |
| SRP159526 | THEM5 | 284486 | RNAseq | 0.5911 | 0.5051 | |
| SRP219564 | THEM5 | 284486 | RNAseq | 0.4021 | 0.7028 | |
| TCGA | THEM5 | 284486 | RNAseq | 0.6929 | 0.1179 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THEM5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of THEM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THEM5 | 284486 | 15 | 0 | 15 | |
| GSE20123 | THEM5 | 284486 | 15 | 0 | 15 | |
| GSE43470 | THEM5 | 284486 | 8 | 2 | 33 | |
| GSE46452 | THEM5 | 284486 | 2 | 1 | 56 | |
| GSE47630 | THEM5 | 284486 | 15 | 0 | 25 | |
| GSE54993 | THEM5 | 284486 | 0 | 4 | 66 | |
| GSE54994 | THEM5 | 284486 | 15 | 0 | 38 | |
| GSE60625 | THEM5 | 284486 | 0 | 0 | 11 | |
| GSE74703 | THEM5 | 284486 | 7 | 1 | 28 | |
| GSE74704 | THEM5 | 284486 | 7 | 0 | 13 | |
| TCGA | THEM5 | 284486 | 39 | 2 | 55 |
Total number of gains: 123; Total number of losses: 10; Total Number of normals: 355.
Somatic mutations of THEM5:
Generating mutation plots.
Highly correlated genes for THEM5:
Showing top 20/37 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THEM5 | PRAM1 | 0.667086 | 3 | 0 | 3 |
| THEM5 | ARMC5 | 0.659447 | 3 | 0 | 3 |
| THEM5 | HNF1A | 0.65324 | 3 | 0 | 3 |
| THEM5 | DLGAP3 | 0.646497 | 3 | 0 | 3 |
| THEM5 | ATF5 | 0.641619 | 3 | 0 | 3 |
| THEM5 | LTB4R2 | 0.635463 | 4 | 0 | 4 |
| THEM5 | IL17RE | 0.633572 | 3 | 0 | 3 |
| THEM5 | SLC6A19 | 0.623507 | 3 | 0 | 3 |
| THEM5 | CNPY1 | 0.620059 | 3 | 0 | 3 |
| THEM5 | CTCFL | 0.617926 | 3 | 0 | 3 |
| THEM5 | APOC2 | 0.614755 | 3 | 0 | 3 |
| THEM5 | YTHDF3-AS1 | 0.604764 | 3 | 0 | 3 |
| THEM5 | ANK1 | 0.604272 | 3 | 0 | 3 |
| THEM5 | AGRP | 0.602735 | 3 | 0 | 3 |
| THEM5 | NOP9 | 0.600343 | 3 | 0 | 3 |
| THEM5 | CYP2W1 | 0.599904 | 3 | 0 | 3 |
| THEM5 | EVX1 | 0.594741 | 3 | 0 | 3 |
| THEM5 | C5AR2 | 0.594195 | 3 | 0 | 3 |
| THEM5 | NKX2-1-AS1 | 0.592944 | 3 | 0 | 3 |
| THEM5 | UPK3A | 0.589645 | 3 | 0 | 3 |
For details and further investigation, click here
