| Full name: distal-less homeobox 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q21.3 | ||
| Entrez ID: 1750 | HGNC ID: HGNC:2919 | Ensembl Gene: ENSG00000006377 | OMIM ID: 600030 |
Expression of DLX6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLX6 | 1750 | 221289_at | -0.2340 | 0.4865 | |
| GSE20347 | DLX6 | 1750 | 221289_at | -0.1011 | 0.2248 | |
| GSE23400 | DLX6 | 1750 | 221289_at | -0.1523 | 0.0011 | |
| GSE26886 | DLX6 | 1750 | 221289_at | -0.2225 | 0.0998 | |
| GSE29001 | DLX6 | 1750 | 221289_at | -0.2580 | 0.0757 | |
| GSE38129 | DLX6 | 1750 | 221289_at | -0.0618 | 0.5231 | |
| GSE45670 | DLX6 | 1750 | 221289_at | 0.0431 | 0.7290 | |
| GSE53622 | DLX6 | 1750 | 14129 | 2.6819 | 0.0000 | |
| GSE53624 | DLX6 | 1750 | 14129 | 3.0023 | 0.0000 | |
| GSE63941 | DLX6 | 1750 | 242940_x_at | 3.1147 | 0.0064 | |
| GSE77861 | DLX6 | 1750 | 221289_at | -0.1514 | 0.3204 | |
| SRP007169 | DLX6 | 1750 | RNAseq | 4.4728 | 0.0002 | |
| SRP133303 | DLX6 | 1750 | RNAseq | 2.2595 | 0.0000 | |
| SRP159526 | DLX6 | 1750 | RNAseq | 5.6475 | 0.0000 | |
| TCGA | DLX6 | 1750 | RNAseq | 3.5628 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by DLX6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLX6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLX6 | 1750 | 13 | 0 | 17 | |
| GSE20123 | DLX6 | 1750 | 13 | 0 | 17 | |
| GSE43470 | DLX6 | 1750 | 8 | 1 | 34 | |
| GSE46452 | DLX6 | 1750 | 12 | 0 | 47 | |
| GSE47630 | DLX6 | 1750 | 9 | 2 | 29 | |
| GSE54993 | DLX6 | 1750 | 1 | 9 | 60 | |
| GSE54994 | DLX6 | 1750 | 16 | 3 | 34 | |
| GSE60625 | DLX6 | 1750 | 0 | 5 | 6 | |
| GSE74703 | DLX6 | 1750 | 7 | 1 | 28 | |
| GSE74704 | DLX6 | 1750 | 9 | 0 | 11 | |
| TCGA | DLX6 | 1750 | 53 | 5 | 38 |
Total number of gains: 141; Total number of losses: 26; Total Number of normals: 321.
Somatic mutations of DLX6:
Generating mutation plots.
Highly correlated genes for DLX6:
Showing top 20/629 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLX6 | FAM131C | 0.742512 | 3 | 0 | 3 |
| DLX6 | BTNL2 | 0.695635 | 5 | 0 | 5 |
| DLX6 | MYCN | 0.689975 | 3 | 0 | 3 |
| DLX6 | IL9R | 0.687773 | 5 | 0 | 5 |
| DLX6 | LINC00930 | 0.677098 | 3 | 0 | 3 |
| DLX6 | NEUROD1 | 0.676917 | 3 | 0 | 3 |
| DLX6 | RBP4 | 0.674145 | 3 | 0 | 3 |
| DLX6 | NTRK3-AS1 | 0.663377 | 3 | 0 | 3 |
| DLX6 | RABEP2 | 0.659136 | 3 | 0 | 3 |
| DLX6 | CA5A | 0.651849 | 5 | 0 | 4 |
| DLX6 | KCNE2 | 0.651431 | 3 | 0 | 3 |
| DLX6 | CEACAM21 | 0.651143 | 5 | 0 | 4 |
| DLX6 | SLC13A3 | 0.650619 | 5 | 0 | 4 |
| DLX6 | EFR3B | 0.650324 | 4 | 0 | 4 |
| DLX6 | IL9 | 0.649465 | 3 | 0 | 3 |
| DLX6 | SLC19A3 | 0.649267 | 4 | 0 | 4 |
| DLX6 | KCNJ13 | 0.647263 | 6 | 0 | 6 |
| DLX6 | ALAS2 | 0.646983 | 4 | 0 | 4 |
| DLX6 | GDF10 | 0.646961 | 3 | 0 | 3 |
| DLX6 | HABP2 | 0.646863 | 4 | 0 | 3 |
For details and further investigation, click here
