| Full name: 5'-aminolevulinate synthase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xp11.21 | ||
| Entrez ID: 212 | HGNC ID: HGNC:397 | Ensembl Gene: ENSG00000158578 | OMIM ID: 301300 |
| Drug and gene relationship at DGIdb | |||
Expression of ALAS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALAS2 | 212 | 211560_s_at | -0.1362 | 0.5729 | |
| GSE20347 | ALAS2 | 212 | 211560_s_at | 0.0187 | 0.7957 | |
| GSE23400 | ALAS2 | 212 | 211560_s_at | -0.0818 | 0.0285 | |
| GSE26886 | ALAS2 | 212 | 211560_s_at | -0.0802 | 0.5115 | |
| GSE29001 | ALAS2 | 212 | 211560_s_at | -0.1783 | 0.1863 | |
| GSE38129 | ALAS2 | 212 | 211560_s_at | -0.1695 | 0.0186 | |
| GSE45670 | ALAS2 | 212 | 211560_s_at | 0.0338 | 0.7254 | |
| GSE53622 | ALAS2 | 212 | 8131 | -0.0159 | 0.9120 | |
| GSE53624 | ALAS2 | 212 | 8131 | -0.1930 | 0.0531 | |
| GSE63941 | ALAS2 | 212 | 211560_s_at | 0.1522 | 0.3954 | |
| GSE77861 | ALAS2 | 212 | 211560_s_at | -0.0295 | 0.7776 | |
| GSE97050 | ALAS2 | 212 | A_32_P385587 | -0.1137 | 0.7831 | |
| SRP133303 | ALAS2 | 212 | RNAseq | -0.1430 | 0.7711 | |
| TCGA | ALAS2 | 212 | RNAseq | -2.4872 | 0.0072 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ALAS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALAS2:
No record found for this gene.
Somatic mutations of ALAS2:
Generating mutation plots.
Highly correlated genes for ALAS2:
Showing top 20/652 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALAS2 | NLRP6 | 0.754165 | 3 | 0 | 3 |
| ALAS2 | MEP1A | 0.748148 | 3 | 0 | 3 |
| ALAS2 | ADIPOQ | 0.744448 | 3 | 0 | 3 |
| ALAS2 | SLC22A11 | 0.721079 | 3 | 0 | 3 |
| ALAS2 | ADAM21 | 0.714013 | 3 | 0 | 3 |
| ALAS2 | PAX7 | 0.711898 | 4 | 0 | 4 |
| ALAS2 | POU1F1 | 0.70929 | 3 | 0 | 3 |
| ALAS2 | WDR78 | 0.703026 | 3 | 0 | 3 |
| ALAS2 | FAM107A | 0.702683 | 3 | 0 | 3 |
| ALAS2 | MAG | 0.700802 | 4 | 0 | 3 |
| ALAS2 | ZNF81 | 0.697682 | 3 | 0 | 3 |
| ALAS2 | SLC26A1 | 0.696678 | 4 | 0 | 4 |
| ALAS2 | HTR6 | 0.69499 | 4 | 0 | 3 |
| ALAS2 | CEBPE | 0.690959 | 3 | 0 | 3 |
| ALAS2 | KRTAP9-9 | 0.687054 | 3 | 0 | 3 |
| ALAS2 | THAP3 | 0.686391 | 3 | 0 | 3 |
| ALAS2 | PHF7 | 0.684725 | 4 | 0 | 3 |
| ALAS2 | ACSBG2 | 0.682908 | 3 | 0 | 3 |
| ALAS2 | LY6H | 0.678208 | 3 | 0 | 3 |
| ALAS2 | FFAR1 | 0.671037 | 3 | 0 | 3 |
For details and further investigation, click here
