KCNJ13

 

Full name: potassium inwardly rectifying channel subfamily J member 13 Alias Symbol: Kir7.1|Kir1.4|LCA16
Type: protein-coding gene Cytoband: 2q37.1
Entrez ID: 3769 HGNC ID: HGNC:6259 Ensembl Gene: ENSG00000115474 OMIM ID: 603208
Drug and gene relationship at DGIdb

 

Expression of KCNJ13:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KCNJ13 3769 210179_at -0.1678 0.4540
GSE20347 KCNJ13 3769 210179_at -0.0196 0.8037
GSE23400 KCNJ13 3769 210179_at -0.1400 0.0000
GSE26886 KCNJ13 3769 210179_at 0.0158 0.9133
GSE29001 KCNJ13 3769 210179_at -0.0349 0.8582
GSE38129 KCNJ13 3769 210179_at -0.1010 0.2531
GSE45670 KCNJ13 3769 210179_at 0.0536 0.5675
GSE53622 KCNJ13 3769 10021 -0.1080 0.2575
GSE53624 KCNJ13 3769 10021 -0.2667 0.0028
GSE63941 KCNJ13 3769 210179_at 0.2585 0.0287
GSE77861 KCNJ13 3769 210179_at -0.1439 0.0795
GSE97050 KCNJ13 3769 A_23_P312752 0.0202 0.9395
SRP133303 KCNJ13 3769 RNAseq 0.2399 0.0783
SRP193095 KCNJ13 3769 RNAseq -0.1140 0.4415
TCGA KCNJ13 3769 RNAseq -1.7812 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by KCNJ13 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of KCNJ13:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KCNJ13 3769 1 12 17
GSE20123 KCNJ13 3769 1 12 17
GSE43470 KCNJ13 3769 1 9 33
GSE46452 KCNJ13 3769 0 5 54
GSE47630 KCNJ13 3769 4 5 31
GSE54993 KCNJ13 3769 3 2 65
GSE54994 KCNJ13 3769 6 10 37
GSE60625 KCNJ13 3769 0 3 8
GSE74703 KCNJ13 3769 1 7 28
GSE74704 KCNJ13 3769 1 5 14
TCGA KCNJ13 3769 11 30 55

Total number of gains: 29; Total number of losses: 100; Total Number of normals: 359.  


 

Somatic mutations of KCNJ13:

 

Generating mutation plots.

 

Highly correlated genes for KCNJ13:

 

Showing top 20/1258 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KCNJ13YY20.886192303
KCNJ13PRSS380.840969303
KCNJ13GDF70.831818303
KCNJ13DCDC10.810129303
KCNJ13KRT770.807145303
KCNJ13OTOG0.804578303
KCNJ13C1QL20.800048303
KCNJ13TTC21A0.798009303
KCNJ13STRC0.793105303
KCNJ13OR4C30.790324303
KCNJ13OR10AD10.785891303
KCNJ13ZC3H100.784985303
KCNJ13PLA2G2C0.783356303
KCNJ13OR13G10.780306303
KCNJ13BSX0.777322303
KCNJ13OR2T270.776813303
KCNJ13CALML60.775148303
KCNJ13LBX20.774143303
KCNJ13DUOXA20.768141404
KCNJ13LCN80.766615403

For details and further investigation, click here