| Full name: neuronal differentiation 1 | Alias Symbol: BETA2|BHF-1|NeuroD|bHLHa3|MODY6 | ||
| Type: protein-coding gene | Cytoband: 2q31.3 | ||
| Entrez ID: 4760 | HGNC ID: HGNC:7762 | Ensembl Gene: ENSG00000162992 | OMIM ID: 601724 |
| Drug and gene relationship at DGIdb | |||
NEUROD1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04950 | Maturity onset diabetes of the young |
Expression of NEUROD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEUROD1 | 4760 | 1556057_s_at | -0.0628 | 0.8213 | |
| GSE20347 | NEUROD1 | 4760 | 206282_at | -0.0239 | 0.6985 | |
| GSE23400 | NEUROD1 | 4760 | 206282_at | -0.0746 | 0.0069 | |
| GSE26886 | NEUROD1 | 4760 | 1556057_s_at | -0.0312 | 0.8021 | |
| GSE29001 | NEUROD1 | 4760 | 206282_at | -0.1180 | 0.3492 | |
| GSE38129 | NEUROD1 | 4760 | 206282_at | -0.1364 | 0.2378 | |
| GSE45670 | NEUROD1 | 4760 | 1556057_s_at | 0.3122 | 0.6587 | |
| GSE53622 | NEUROD1 | 4760 | 17810 | 0.1068 | 0.3196 | |
| GSE53624 | NEUROD1 | 4760 | 17810 | 0.0740 | 0.3286 | |
| GSE63941 | NEUROD1 | 4760 | 1556057_s_at | -0.0509 | 0.7062 | |
| GSE77861 | NEUROD1 | 4760 | 1556057_s_at | -0.1006 | 0.3105 | |
| SRP133303 | NEUROD1 | 4760 | RNAseq | -0.0810 | 0.8264 | |
| TCGA | NEUROD1 | 4760 | RNAseq | -4.5090 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NEUROD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEUROD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEUROD1 | 4760 | 5 | 1 | 24 | |
| GSE20123 | NEUROD1 | 4760 | 5 | 1 | 24 | |
| GSE43470 | NEUROD1 | 4760 | 5 | 1 | 37 | |
| GSE46452 | NEUROD1 | 4760 | 1 | 4 | 54 | |
| GSE47630 | NEUROD1 | 4760 | 4 | 4 | 32 | |
| GSE54993 | NEUROD1 | 4760 | 0 | 5 | 65 | |
| GSE54994 | NEUROD1 | 4760 | 12 | 5 | 36 | |
| GSE60625 | NEUROD1 | 4760 | 0 | 3 | 8 | |
| GSE74703 | NEUROD1 | 4760 | 4 | 1 | 31 | |
| GSE74704 | NEUROD1 | 4760 | 2 | 1 | 17 | |
| TCGA | NEUROD1 | 4760 | 26 | 8 | 62 |
Total number of gains: 64; Total number of losses: 34; Total Number of normals: 390.
Somatic mutations of NEUROD1:
Generating mutation plots.
Highly correlated genes for NEUROD1:
Showing top 20/364 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEUROD1 | IL1RAPL1 | 0.731995 | 3 | 0 | 3 |
| NEUROD1 | DCC | 0.705024 | 4 | 0 | 4 |
| NEUROD1 | CSN2 | 0.692965 | 3 | 0 | 3 |
| NEUROD1 | OR6A2 | 0.692178 | 3 | 0 | 3 |
| NEUROD1 | KRTAP4-7 | 0.692054 | 4 | 0 | 4 |
| NEUROD1 | CA8 | 0.689591 | 4 | 0 | 4 |
| NEUROD1 | OR2W1 | 0.677718 | 3 | 0 | 3 |
| NEUROD1 | SULT2A1 | 0.677499 | 4 | 0 | 3 |
| NEUROD1 | DLX6 | 0.676917 | 3 | 0 | 3 |
| NEUROD1 | OR2H2 | 0.672176 | 4 | 0 | 4 |
| NEUROD1 | MUC5AC | 0.668413 | 5 | 0 | 4 |
| NEUROD1 | MAPK8IP2 | 0.668162 | 3 | 0 | 3 |
| NEUROD1 | GPR31 | 0.668066 | 3 | 0 | 3 |
| NEUROD1 | NPPA | 0.665329 | 4 | 0 | 4 |
| NEUROD1 | CCKBR | 0.665077 | 4 | 0 | 4 |
| NEUROD1 | DNAAF1 | 0.664539 | 3 | 0 | 3 |
| NEUROD1 | RUNX2 | 0.663131 | 3 | 0 | 3 |
| NEUROD1 | GPC5 | 0.662397 | 5 | 0 | 4 |
| NEUROD1 | SLC6A13 | 0.661426 | 4 | 0 | 4 |
| NEUROD1 | CDC14A | 0.659051 | 3 | 0 | 3 |
For details and further investigation, click here
