| Full name: EFR3 homolog B | Alias Symbol: FLJ37871 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 22979 | HGNC ID: HGNC:29155 | Ensembl Gene: ENSG00000084710 | OMIM ID: 616797 |
| Drug and gene relationship at DGIdb | |||
Expression of EFR3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFR3B | 22979 | 215334_at | -0.1287 | 0.6428 | |
| GSE20347 | EFR3B | 22979 | 215328_at | 0.1046 | 0.3206 | |
| GSE23400 | EFR3B | 22979 | 215334_at | -0.1217 | 0.0015 | |
| GSE26886 | EFR3B | 22979 | 227283_at | 0.2016 | 0.0957 | |
| GSE29001 | EFR3B | 22979 | 215334_at | -0.1685 | 0.2366 | |
| GSE38129 | EFR3B | 22979 | 215328_at | -0.0311 | 0.8567 | |
| GSE45670 | EFR3B | 22979 | 227283_at | 0.1032 | 0.4178 | |
| GSE53622 | EFR3B | 22979 | 76401 | 0.2762 | 0.0450 | |
| GSE53624 | EFR3B | 22979 | 76401 | 0.6535 | 0.0000 | |
| GSE63941 | EFR3B | 22979 | 227283_at | -0.2905 | 0.4223 | |
| GSE77861 | EFR3B | 22979 | 227283_at | 0.1792 | 0.1361 | |
| GSE97050 | EFR3B | 22979 | A_33_P3373614 | 0.1681 | 0.7645 | |
| SRP007169 | EFR3B | 22979 | RNAseq | 2.5267 | 0.0056 | |
| SRP064894 | EFR3B | 22979 | RNAseq | 0.9452 | 0.0046 | |
| SRP133303 | EFR3B | 22979 | RNAseq | 0.6282 | 0.0352 | |
| SRP193095 | EFR3B | 22979 | RNAseq | 0.2949 | 0.0397 | |
| SRP219564 | EFR3B | 22979 | RNAseq | 0.4621 | 0.3861 | |
| TCGA | EFR3B | 22979 | RNAseq | -0.4820 | 0.0054 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EFR3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFR3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFR3B | 22979 | 11 | 2 | 17 | |
| GSE20123 | EFR3B | 22979 | 11 | 2 | 17 | |
| GSE43470 | EFR3B | 22979 | 3 | 1 | 39 | |
| GSE46452 | EFR3B | 22979 | 3 | 4 | 52 | |
| GSE47630 | EFR3B | 22979 | 8 | 0 | 32 | |
| GSE54993 | EFR3B | 22979 | 0 | 6 | 64 | |
| GSE54994 | EFR3B | 22979 | 10 | 0 | 43 | |
| GSE60625 | EFR3B | 22979 | 0 | 3 | 8 | |
| GSE74703 | EFR3B | 22979 | 3 | 0 | 33 | |
| GSE74704 | EFR3B | 22979 | 9 | 1 | 10 | |
| TCGA | EFR3B | 22979 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of EFR3B:
Generating mutation plots.
Highly correlated genes for EFR3B:
Showing top 20/501 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFR3B | TNFSF9 | 0.835487 | 3 | 0 | 3 |
| EFR3B | TCL6 | 0.80682 | 3 | 0 | 3 |
| EFR3B | ATF7 | 0.76412 | 4 | 0 | 4 |
| EFR3B | ZNF460 | 0.728234 | 6 | 0 | 6 |
| EFR3B | OR2F1 | 0.713931 | 4 | 0 | 3 |
| EFR3B | PAPPA2 | 0.703479 | 4 | 0 | 4 |
| EFR3B | RBM24 | 0.702981 | 3 | 0 | 3 |
| EFR3B | KIR2DL5A | 0.701974 | 4 | 0 | 3 |
| EFR3B | HAO2 | 0.694733 | 4 | 0 | 4 |
| EFR3B | GTF2H3 | 0.69304 | 4 | 0 | 3 |
| EFR3B | TRPV5 | 0.689527 | 4 | 0 | 4 |
| EFR3B | GH2 | 0.685789 | 5 | 0 | 5 |
| EFR3B | CRISP1 | 0.682777 | 4 | 0 | 4 |
| EFR3B | CHST4 | 0.682259 | 4 | 0 | 4 |
| EFR3B | MYL3 | 0.679316 | 3 | 0 | 3 |
| EFR3B | ADAM11 | 0.678954 | 6 | 0 | 5 |
| EFR3B | COLEC10 | 0.678689 | 4 | 0 | 4 |
| EFR3B | NTRK3 | 0.676665 | 4 | 0 | 4 |
| EFR3B | ARR3 | 0.676569 | 4 | 0 | 4 |
| EFR3B | LATS1 | 0.672501 | 3 | 0 | 3 |
For details and further investigation, click here
