RABEP2

 

Full name: rabaptin, RAB GTPase binding effector protein 2 Alias Symbol: FRA|FLJ23282
Type: protein-coding gene Cytoband: 16p11.2
Entrez ID: 79874 HGNC ID: HGNC:24817 Ensembl Gene: ENSG00000177548 OMIM ID: 611869
Drug and gene relationship at DGIdb

 

Expression of RABEP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RABEP2 79874 74694_s_at 0.1174 0.8607
GSE20347 RABEP2 79874 74694_s_at -0.1406 0.4003
GSE23400 RABEP2 79874 77508_r_at -0.1718 0.0000
GSE26886 RABEP2 79874 77508_r_at 0.0667 0.7032
GSE29001 RABEP2 79874 77508_r_at -0.4089 0.0249
GSE38129 RABEP2 79874 74694_s_at -0.0879 0.5443
GSE45670 RABEP2 79874 74694_s_at 0.1404 0.3636
GSE63941 RABEP2 79874 74694_s_at -1.2924 0.0290
GSE77861 RABEP2 79874 77508_r_at -0.1814 0.0826
GSE97050 RABEP2 79874 A_33_P3239152 0.2016 0.3487
SRP007169 RABEP2 79874 RNAseq -0.8290 0.0484
SRP008496 RABEP2 79874 RNAseq -0.6276 0.0135
SRP064894 RABEP2 79874 RNAseq 0.2360 0.3437
SRP133303 RABEP2 79874 RNAseq 0.0376 0.8656
SRP159526 RABEP2 79874 RNAseq 0.0268 0.8837
SRP193095 RABEP2 79874 RNAseq 0.0151 0.9015
SRP219564 RABEP2 79874 RNAseq 0.0586 0.7740
TCGA RABEP2 79874 RNAseq -0.0808 0.1616

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by RABEP2 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of RABEP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RABEP2 79874 5 5 20
GSE20123 RABEP2 79874 5 4 21
GSE43470 RABEP2 79874 3 3 37
GSE46452 RABEP2 79874 38 1 20
GSE47630 RABEP2 79874 11 7 22
GSE54993 RABEP2 79874 3 5 62
GSE54994 RABEP2 79874 5 9 39
GSE60625 RABEP2 79874 4 0 7
GSE74703 RABEP2 79874 3 2 31
GSE74704 RABEP2 79874 3 2 15
TCGA RABEP2 79874 20 12 64

Total number of gains: 100; Total number of losses: 50; Total Number of normals: 338.  


 

Somatic mutations of RABEP2:

 

Generating mutation plots.

 

Highly correlated genes for RABEP2:

 

Showing top 20/673 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RABEP2ZNF5780.795021404
RABEP2PPFIA20.790962303
RABEP2PUS100.790732303
RABEP2HHLA10.771274404
RABEP2TAF100.771219303
RABEP2VPS520.771114504
RABEP2CNTF0.77059303
RABEP2DTD10.769051303
RABEP2LRTOMT0.7685303
RABEP2SUFU0.76655404
RABEP2C1orf1220.761656303
RABEP2AMBN0.759279404
RABEP2MAZ0.758651303
RABEP2TMEM120A0.757669404
RABEP2BTN1A10.753918303
RABEP2MOSPD30.753229605
RABEP2CBL0.749333303
RABEP2CAMK1G0.749296404
RABEP2ZNF518A0.747023303
RABEP2TIMM230.745731303

For details and further investigation, click here