| Full name: dynein axonemal heavy chain 8 | Alias Symbol: hdhc9 | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 1769 | HGNC ID: HGNC:2952 | Ensembl Gene: ENSG00000124721 | OMIM ID: 603337 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAH8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAH8 | 1769 | 233052_at | 0.0706 | 0.7873 | |
| GSE26886 | DNAH8 | 1769 | 233052_at | 0.0671 | 0.7201 | |
| GSE45670 | DNAH8 | 1769 | 233052_at | 0.0141 | 0.9079 | |
| GSE53622 | DNAH8 | 1769 | 38478 | 0.0246 | 0.8395 | |
| GSE53624 | DNAH8 | 1769 | 54965 | 0.9353 | 0.0000 | |
| GSE63941 | DNAH8 | 1769 | 233052_at | -0.2320 | 0.1692 | |
| GSE77861 | DNAH8 | 1769 | 233052_at | -0.0925 | 0.3490 | |
| TCGA | DNAH8 | 1769 | RNAseq | -0.6328 | 0.5399 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAH8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAH8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAH8 | 1769 | 5 | 2 | 23 | |
| GSE20123 | DNAH8 | 1769 | 5 | 2 | 23 | |
| GSE43470 | DNAH8 | 1769 | 6 | 0 | 37 | |
| GSE46452 | DNAH8 | 1769 | 2 | 9 | 48 | |
| GSE47630 | DNAH8 | 1769 | 8 | 4 | 28 | |
| GSE54993 | DNAH8 | 1769 | 3 | 2 | 65 | |
| GSE54994 | DNAH8 | 1769 | 11 | 4 | 38 | |
| GSE60625 | DNAH8 | 1769 | 0 | 1 | 10 | |
| GSE74703 | DNAH8 | 1769 | 6 | 0 | 30 | |
| GSE74704 | DNAH8 | 1769 | 1 | 2 | 17 | |
| TCGA | DNAH8 | 1769 | 18 | 15 | 63 |
Total number of gains: 65; Total number of losses: 41; Total Number of normals: 382.
Somatic mutations of DNAH8:
Generating mutation plots.
Highly correlated genes for DNAH8:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAH8 | TMEM235 | 0.704073 | 3 | 0 | 3 |
| DNAH8 | CYGB | 0.703995 | 3 | 0 | 3 |
| DNAH8 | CA7 | 0.68994 | 3 | 0 | 3 |
| DNAH8 | MCEMP1 | 0.661025 | 3 | 0 | 3 |
| DNAH8 | GLIS3-AS1 | 0.632036 | 3 | 0 | 3 |
| DNAH8 | TNP2 | 0.625235 | 3 | 0 | 3 |
| DNAH8 | TEKT1 | 0.601748 | 4 | 0 | 3 |
| DNAH8 | PRM2 | 0.590242 | 3 | 0 | 3 |
| DNAH8 | GPR26 | 0.589026 | 4 | 0 | 3 |
| DNAH8 | STK32A | 0.586723 | 3 | 0 | 3 |
| DNAH8 | DPEP3 | 0.585641 | 3 | 0 | 3 |
| DNAH8 | WWC2-AS2 | 0.585497 | 3 | 0 | 3 |
| DNAH8 | AVPR2 | 0.571188 | 4 | 0 | 3 |
| DNAH8 | GRID1 | 0.567231 | 4 | 0 | 3 |
| DNAH8 | F2RL3 | 0.560584 | 3 | 0 | 3 |
| DNAH8 | LINC01013 | 0.556922 | 3 | 0 | 3 |
| DNAH8 | SLC17A9 | 0.545673 | 4 | 0 | 3 |
| DNAH8 | OSM | 0.539454 | 3 | 0 | 3 |
| DNAH8 | GIPC3 | 0.533366 | 3 | 0 | 3 |
| DNAH8 | RS1 | 0.531857 | 4 | 0 | 3 |
For details and further investigation, click here
