| Full name: serine/threonine kinase 32A | Alias Symbol: MGC22688|YANK1 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 202374 | HGNC ID: HGNC:28317 | Ensembl Gene: ENSG00000169302 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of STK32A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK32A | 202374 | 229866_at | -0.1067 | 0.7009 | |
| GSE26886 | STK32A | 202374 | 229866_at | -0.1069 | 0.4239 | |
| GSE45670 | STK32A | 202374 | 229866_at | 0.0129 | 0.9409 | |
| GSE53622 | STK32A | 202374 | 41825 | -0.9551 | 0.0000 | |
| GSE53624 | STK32A | 202374 | 41825 | -0.3623 | 0.0001 | |
| GSE63941 | STK32A | 202374 | 229866_at | 0.0781 | 0.8262 | |
| GSE77861 | STK32A | 202374 | 229866_at | -0.1450 | 0.1918 | |
| GSE97050 | STK32A | 202374 | A_23_P355394 | -0.6608 | 0.2211 | |
| SRP133303 | STK32A | 202374 | RNAseq | 1.3640 | 0.0128 | |
| SRP159526 | STK32A | 202374 | RNAseq | 0.9642 | 0.0978 | |
| TCGA | STK32A | 202374 | RNAseq | -2.7885 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by STK32A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK32A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK32A | 202374 | 1 | 12 | 17 | |
| GSE20123 | STK32A | 202374 | 1 | 12 | 17 | |
| GSE43470 | STK32A | 202374 | 2 | 9 | 32 | |
| GSE46452 | STK32A | 202374 | 0 | 27 | 32 | |
| GSE47630 | STK32A | 202374 | 0 | 20 | 20 | |
| GSE54993 | STK32A | 202374 | 9 | 1 | 60 | |
| GSE54994 | STK32A | 202374 | 2 | 15 | 36 | |
| GSE60625 | STK32A | 202374 | 0 | 0 | 11 | |
| GSE74703 | STK32A | 202374 | 2 | 7 | 27 | |
| GSE74704 | STK32A | 202374 | 1 | 7 | 12 | |
| TCGA | STK32A | 202374 | 3 | 40 | 53 |
Total number of gains: 21; Total number of losses: 150; Total Number of normals: 317.
Somatic mutations of STK32A:
Generating mutation plots.
Highly correlated genes for STK32A:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK32A | SMYD1 | 0.770867 | 3 | 0 | 3 |
| STK32A | APC2 | 0.732972 | 3 | 0 | 3 |
| STK32A | SLC35F1 | 0.72555 | 3 | 0 | 3 |
| STK32A | RASD2 | 0.713613 | 3 | 0 | 3 |
| STK32A | ANKS1B | 0.705628 | 3 | 0 | 3 |
| STK32A | HS6ST3 | 0.693733 | 4 | 0 | 3 |
| STK32A | PDZD4 | 0.689807 | 4 | 0 | 4 |
| STK32A | GIPC3 | 0.688798 | 4 | 0 | 4 |
| STK32A | ZMAT4 | 0.685908 | 4 | 0 | 3 |
| STK32A | KHDRBS2 | 0.685382 | 3 | 0 | 3 |
| STK32A | PCDH11X | 0.68129 | 3 | 0 | 3 |
| STK32A | SNPH | 0.67937 | 4 | 0 | 3 |
| STK32A | EBF2 | 0.677086 | 3 | 0 | 3 |
| STK32A | PPP1R14A | 0.669698 | 4 | 0 | 4 |
| STK32A | ACACB | 0.663749 | 5 | 0 | 3 |
| STK32A | TTLL7 | 0.658129 | 4 | 0 | 3 |
| STK32A | SPAG8 | 0.656496 | 3 | 0 | 3 |
| STK32A | ABCC8 | 0.655849 | 3 | 0 | 3 |
| STK32A | SOD3 | 0.651268 | 3 | 0 | 3 |
| STK32A | ADCYAP1R1 | 0.647441 | 5 | 0 | 4 |
For details and further investigation, click here
