| Full name: GIPC PDZ domain containing family member 3 | Alias Symbol: DFNB95 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126326 | HGNC ID: HGNC:18183 | Ensembl Gene: ENSG00000179855 | OMIM ID: 608792 |
| Drug and gene relationship at DGIdb | |||
Expression of GIPC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GIPC3 | 126326 | 236730_at | -0.1758 | 0.5785 | |
| GSE26886 | GIPC3 | 126326 | 236730_at | 0.2042 | 0.1489 | |
| GSE45670 | GIPC3 | 126326 | 236730_at | 0.0261 | 0.7475 | |
| GSE53622 | GIPC3 | 126326 | 67770 | -0.8990 | 0.0000 | |
| GSE53624 | GIPC3 | 126326 | 67770 | -0.0782 | 0.3207 | |
| GSE63941 | GIPC3 | 126326 | 236730_at | 0.1600 | 0.4497 | |
| GSE77861 | GIPC3 | 126326 | 236730_at | -0.0469 | 0.6956 | |
| GSE97050 | GIPC3 | 126326 | A_24_P118527 | -0.1988 | 0.5619 | |
| SRP064894 | GIPC3 | 126326 | RNAseq | -0.9078 | 0.0020 | |
| SRP133303 | GIPC3 | 126326 | RNAseq | -1.3601 | 0.0002 | |
| SRP159526 | GIPC3 | 126326 | RNAseq | -1.1009 | 0.0046 | |
| SRP219564 | GIPC3 | 126326 | RNAseq | -2.2161 | 0.0218 | |
| TCGA | GIPC3 | 126326 | RNAseq | -0.6318 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by GIPC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GIPC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GIPC3 | 126326 | 5 | 3 | 22 | |
| GSE20123 | GIPC3 | 126326 | 4 | 2 | 24 | |
| GSE43470 | GIPC3 | 126326 | 1 | 9 | 33 | |
| GSE46452 | GIPC3 | 126326 | 47 | 1 | 11 | |
| GSE47630 | GIPC3 | 126326 | 5 | 7 | 28 | |
| GSE54993 | GIPC3 | 126326 | 16 | 3 | 51 | |
| GSE54994 | GIPC3 | 126326 | 8 | 16 | 29 | |
| GSE60625 | GIPC3 | 126326 | 9 | 0 | 2 | |
| GSE74703 | GIPC3 | 126326 | 1 | 6 | 29 | |
| GSE74704 | GIPC3 | 126326 | 1 | 2 | 17 | |
| TCGA | GIPC3 | 126326 | 10 | 19 | 67 |
Total number of gains: 107; Total number of losses: 68; Total Number of normals: 313.
Somatic mutations of GIPC3:
Generating mutation plots.
Highly correlated genes for GIPC3:
Showing top 20/425 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GIPC3 | KATNAL1 | 0.79206 | 3 | 0 | 3 |
| GIPC3 | CASQ1 | 0.788576 | 3 | 0 | 3 |
| GIPC3 | IL17B | 0.782884 | 3 | 0 | 3 |
| GIPC3 | ZNF385D | 0.77733 | 3 | 0 | 3 |
| GIPC3 | ADAMTSL1 | 0.774325 | 3 | 0 | 3 |
| GIPC3 | VIP | 0.773787 | 3 | 0 | 3 |
| GIPC3 | DGKB | 0.767547 | 4 | 0 | 4 |
| GIPC3 | MTURN | 0.75972 | 3 | 0 | 3 |
| GIPC3 | DACT3 | 0.755721 | 3 | 0 | 3 |
| GIPC3 | CSRNP1 | 0.754811 | 3 | 0 | 3 |
| GIPC3 | ABRA | 0.753762 | 3 | 0 | 3 |
| GIPC3 | FABP3 | 0.752637 | 4 | 0 | 4 |
| GIPC3 | ITGA7 | 0.745824 | 3 | 0 | 3 |
| GIPC3 | TOX | 0.744523 | 3 | 0 | 3 |
| GIPC3 | TMEM88 | 0.743964 | 3 | 0 | 3 |
| GIPC3 | DNAJB5 | 0.743303 | 4 | 0 | 4 |
| GIPC3 | JAZF1-AS1 | 0.739965 | 3 | 0 | 3 |
| GIPC3 | PDE3A | 0.731853 | 4 | 0 | 4 |
| GIPC3 | C3orf18 | 0.731672 | 3 | 0 | 3 |
| GIPC3 | SNPH | 0.730067 | 4 | 0 | 3 |
For details and further investigation, click here
