| Full name: cytoglobin | Alias Symbol: HGB|STAP | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 114757 | HGNC ID: HGNC:16505 | Ensembl Gene: ENSG00000161544 | OMIM ID: 608759 |
| Drug and gene relationship at DGIdb | |||
Expression of CYGB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYGB | 114757 | 226632_at | 0.0353 | 0.9656 | |
| GSE26886 | CYGB | 114757 | 1570410_at | 0.0466 | 0.7698 | |
| GSE45670 | CYGB | 114757 | 226632_at | -0.5831 | 0.0104 | |
| GSE53622 | CYGB | 114757 | 144326 | -0.3857 | 0.0000 | |
| GSE53624 | CYGB | 114757 | 144326 | -0.0744 | 0.4286 | |
| GSE63941 | CYGB | 114757 | 1553572_a_at | 0.0178 | 0.9194 | |
| GSE77861 | CYGB | 114757 | 1570410_at | -0.0459 | 0.5613 | |
| GSE97050 | CYGB | 114757 | A_33_P3285868 | -0.0873 | 0.7587 | |
| SRP007169 | CYGB | 114757 | RNAseq | 1.5247 | 0.0406 | |
| SRP064894 | CYGB | 114757 | RNAseq | 0.4918 | 0.0769 | |
| SRP133303 | CYGB | 114757 | RNAseq | -0.0964 | 0.6234 | |
| SRP159526 | CYGB | 114757 | RNAseq | 0.3219 | 0.4581 | |
| SRP193095 | CYGB | 114757 | RNAseq | 0.5497 | 0.1225 | |
| SRP219564 | CYGB | 114757 | RNAseq | 0.4114 | 0.4820 | |
| TCGA | CYGB | 114757 | RNAseq | -0.2920 | 0.0036 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CYGB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYGB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYGB | 114757 | 7 | 2 | 21 | |
| GSE20123 | CYGB | 114757 | 7 | 2 | 21 | |
| GSE43470 | CYGB | 114757 | 5 | 3 | 35 | |
| GSE46452 | CYGB | 114757 | 33 | 1 | 25 | |
| GSE47630 | CYGB | 114757 | 8 | 1 | 31 | |
| GSE54993 | CYGB | 114757 | 2 | 5 | 63 | |
| GSE54994 | CYGB | 114757 | 10 | 4 | 39 | |
| GSE60625 | CYGB | 114757 | 6 | 0 | 5 | |
| GSE74703 | CYGB | 114757 | 5 | 1 | 30 | |
| GSE74704 | CYGB | 114757 | 5 | 1 | 14 | |
| TCGA | CYGB | 114757 | 31 | 10 | 55 |
Total number of gains: 119; Total number of losses: 30; Total Number of normals: 339.
Somatic mutations of CYGB:
Generating mutation plots.
Highly correlated genes for CYGB:
Showing top 20/152 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYGB | FZD4 | 0.819418 | 3 | 0 | 3 |
| CYGB | CD200 | 0.749543 | 3 | 0 | 3 |
| CYGB | ADPRH | 0.748683 | 3 | 0 | 3 |
| CYGB | VSTM4 | 0.741981 | 3 | 0 | 3 |
| CYGB | B3GALT2 | 0.741539 | 3 | 0 | 3 |
| CYGB | EPDR1 | 0.737835 | 3 | 0 | 3 |
| CYGB | THSD7A | 0.735946 | 3 | 0 | 3 |
| CYGB | EBF1 | 0.732859 | 3 | 0 | 3 |
| CYGB | PPP5C | 0.727644 | 3 | 0 | 3 |
| CYGB | FAM167B | 0.720283 | 4 | 0 | 4 |
| CYGB | CAV3 | 0.718602 | 3 | 0 | 3 |
| CYGB | AGT | 0.711615 | 3 | 0 | 3 |
| CYGB | CALCRL | 0.706053 | 3 | 0 | 3 |
| CYGB | DNAH8 | 0.703995 | 3 | 0 | 3 |
| CYGB | SRPX | 0.703042 | 3 | 0 | 3 |
| CYGB | ENTPD2 | 0.700995 | 3 | 0 | 3 |
| CYGB | SOX5 | 0.698077 | 4 | 0 | 4 |
| CYGB | SLC32A1 | 0.696769 | 3 | 0 | 3 |
| CYGB | SERPINA5 | 0.694894 | 4 | 0 | 4 |
| CYGB | IRF2 | 0.6944 | 3 | 0 | 3 |
For details and further investigation, click here
