| Full name: transcriptional adaptor 2B | Alias Symbol: MGC21874 | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 93624 | HGNC ID: HGNC:30781 | Ensembl Gene: ENSG00000173011 | OMIM ID: 608790 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TADA2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TADA2B | 93624 | 236248_x_at | -0.2138 | 0.7503 | |
| GSE26886 | TADA2B | 93624 | 226240_at | -0.8452 | 0.0059 | |
| GSE45670 | TADA2B | 93624 | 226240_at | -0.0940 | 0.5717 | |
| GSE53622 | TADA2B | 93624 | 7758 | -0.6150 | 0.0000 | |
| GSE53624 | TADA2B | 93624 | 7758 | -0.7069 | 0.0000 | |
| GSE63941 | TADA2B | 93624 | 226240_at | -0.1313 | 0.7056 | |
| GSE77861 | TADA2B | 93624 | 226240_at | -0.1959 | 0.1411 | |
| GSE97050 | TADA2B | 93624 | A_24_P687582 | -0.3769 | 0.1839 | |
| SRP007169 | TADA2B | 93624 | RNAseq | -1.1799 | 0.0032 | |
| SRP008496 | TADA2B | 93624 | RNAseq | -1.3086 | 0.0000 | |
| SRP064894 | TADA2B | 93624 | RNAseq | -0.4409 | 0.0020 | |
| SRP133303 | TADA2B | 93624 | RNAseq | -0.4968 | 0.0005 | |
| SRP159526 | TADA2B | 93624 | RNAseq | -0.5640 | 0.0001 | |
| SRP193095 | TADA2B | 93624 | RNAseq | -0.5924 | 0.0000 | |
| SRP219564 | TADA2B | 93624 | RNAseq | -0.5265 | 0.0173 | |
| TCGA | TADA2B | 93624 | RNAseq | -0.3903 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TADA2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TADA2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TADA2B | 93624 | 0 | 18 | 12 | |
| GSE20123 | TADA2B | 93624 | 0 | 18 | 12 | |
| GSE43470 | TADA2B | 93624 | 0 | 17 | 26 | |
| GSE46452 | TADA2B | 93624 | 1 | 36 | 22 | |
| GSE47630 | TADA2B | 93624 | 1 | 19 | 20 | |
| GSE54993 | TADA2B | 93624 | 10 | 0 | 60 | |
| GSE54994 | TADA2B | 93624 | 3 | 12 | 38 | |
| GSE60625 | TADA2B | 93624 | 0 | 0 | 11 | |
| GSE74703 | TADA2B | 93624 | 0 | 13 | 23 | |
| GSE74704 | TADA2B | 93624 | 0 | 10 | 10 | |
| TCGA | TADA2B | 93624 | 7 | 48 | 41 |
Total number of gains: 22; Total number of losses: 191; Total Number of normals: 275.
Somatic mutations of TADA2B:
Generating mutation plots.
Highly correlated genes for TADA2B:
Showing top 20/759 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TADA2B | ASH1L | 0.762876 | 3 | 0 | 3 |
| TADA2B | FHL5 | 0.745742 | 3 | 0 | 3 |
| TADA2B | USP19 | 0.740818 | 3 | 0 | 3 |
| TADA2B | AP3S2 | 0.737888 | 3 | 0 | 3 |
| TADA2B | USP33 | 0.737885 | 3 | 0 | 3 |
| TADA2B | LIFR | 0.735422 | 3 | 0 | 3 |
| TADA2B | PREX2 | 0.735123 | 3 | 0 | 3 |
| TADA2B | C2CD2 | 0.731902 | 3 | 0 | 3 |
| TADA2B | CTDSPL | 0.730854 | 5 | 0 | 5 |
| TADA2B | MACROD2 | 0.727794 | 3 | 0 | 3 |
| TADA2B | ANO5 | 0.723592 | 3 | 0 | 3 |
| TADA2B | BBIP1 | 0.723124 | 3 | 0 | 3 |
| TADA2B | STAT5A | 0.721064 | 4 | 0 | 4 |
| TADA2B | IFT46 | 0.720141 | 3 | 0 | 3 |
| TADA2B | GGA3 | 0.719049 | 3 | 0 | 3 |
| TADA2B | RNASEH2B | 0.717825 | 3 | 0 | 3 |
| TADA2B | RNF4 | 0.717732 | 4 | 0 | 4 |
| TADA2B | KLHDC2 | 0.717679 | 4 | 0 | 3 |
| TADA2B | PHF11 | 0.715127 | 3 | 0 | 3 |
| TADA2B | ADH1B | 0.712071 | 3 | 0 | 3 |
For details and further investigation, click here
