| Full name: BCL2 associated athanogene 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 573 | HGNC ID: HGNC:937 | Ensembl Gene: ENSG00000107262 | OMIM ID: 601497 |
| Drug and gene relationship at DGIdb | |||
Expression of BAG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BAG1 | 573 | 202387_at | -0.5184 | 0.3839 | |
| GSE20347 | BAG1 | 573 | 202387_at | -0.6290 | 0.0003 | |
| GSE23400 | BAG1 | 573 | 202387_at | -0.3861 | 0.0000 | |
| GSE26886 | BAG1 | 573 | 202387_at | -0.0174 | 0.9413 | |
| GSE29001 | BAG1 | 573 | 202387_at | -0.5725 | 0.0443 | |
| GSE38129 | BAG1 | 573 | 202387_at | -0.6359 | 0.0003 | |
| GSE45670 | BAG1 | 573 | 202387_at | -0.4034 | 0.0069 | |
| GSE53622 | BAG1 | 573 | 32100 | -0.8084 | 0.0000 | |
| GSE53624 | BAG1 | 573 | 32100 | -0.5076 | 0.0000 | |
| GSE63941 | BAG1 | 573 | 211475_s_at | -0.4350 | 0.5825 | |
| GSE77861 | BAG1 | 573 | 202387_at | -0.0555 | 0.9219 | |
| GSE97050 | BAG1 | 573 | A_23_P146654 | -0.6014 | 0.1143 | |
| SRP007169 | BAG1 | 573 | RNAseq | -1.5976 | 0.0000 | |
| SRP008496 | BAG1 | 573 | RNAseq | -0.9972 | 0.0005 | |
| SRP064894 | BAG1 | 573 | RNAseq | -0.7986 | 0.0012 | |
| SRP133303 | BAG1 | 573 | RNAseq | -0.7108 | 0.0000 | |
| SRP159526 | BAG1 | 573 | RNAseq | -1.0529 | 0.0082 | |
| SRP193095 | BAG1 | 573 | RNAseq | -0.9358 | 0.0000 | |
| SRP219564 | BAG1 | 573 | RNAseq | -0.3502 | 0.3255 | |
| TCGA | BAG1 | 573 | RNAseq | -0.2169 | 0.0042 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by BAG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BAG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BAG1 | 573 | 3 | 13 | 14 | |
| GSE20123 | BAG1 | 573 | 3 | 13 | 14 | |
| GSE43470 | BAG1 | 573 | 3 | 10 | 30 | |
| GSE46452 | BAG1 | 573 | 7 | 15 | 37 | |
| GSE47630 | BAG1 | 573 | 1 | 21 | 18 | |
| GSE54993 | BAG1 | 573 | 6 | 0 | 64 | |
| GSE54994 | BAG1 | 573 | 7 | 11 | 35 | |
| GSE60625 | BAG1 | 573 | 0 | 0 | 11 | |
| GSE74703 | BAG1 | 573 | 2 | 7 | 27 | |
| GSE74704 | BAG1 | 573 | 0 | 10 | 10 | |
| TCGA | BAG1 | 573 | 16 | 44 | 36 |
Total number of gains: 48; Total number of losses: 144; Total Number of normals: 296.
Somatic mutations of BAG1:
Generating mutation plots.
Highly correlated genes for BAG1:
Showing top 20/822 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BAG1 | ICA1L | 0.770978 | 3 | 0 | 3 |
| BAG1 | ZNF844 | 0.753691 | 4 | 0 | 4 |
| BAG1 | ZNF528 | 0.753184 | 3 | 0 | 3 |
| BAG1 | CELF6 | 0.750518 | 3 | 0 | 3 |
| BAG1 | HDHD2 | 0.734488 | 3 | 0 | 3 |
| BAG1 | FBXL14 | 0.733666 | 3 | 0 | 3 |
| BAG1 | ZNF510 | 0.726228 | 3 | 0 | 3 |
| BAG1 | DNAJC21 | 0.723834 | 3 | 0 | 3 |
| BAG1 | MRPS36 | 0.723579 | 3 | 0 | 3 |
| BAG1 | MRPL2 | 0.720665 | 3 | 0 | 3 |
| BAG1 | DNAJC24 | 0.714986 | 3 | 0 | 3 |
| BAG1 | CCDC159 | 0.711345 | 4 | 0 | 3 |
| BAG1 | EPC1 | 0.708523 | 4 | 0 | 3 |
| BAG1 | ASB8 | 0.706075 | 6 | 0 | 6 |
| BAG1 | ZNF480 | 0.705654 | 3 | 0 | 3 |
| BAG1 | MRPS33 | 0.704089 | 3 | 0 | 3 |
| BAG1 | CDC37L1 | 0.703569 | 7 | 0 | 6 |
| BAG1 | CAPN7 | 0.703366 | 6 | 0 | 6 |
| BAG1 | CLEC3B | 0.701569 | 3 | 0 | 3 |
| BAG1 | MBNL3 | 0.701332 | 3 | 0 | 3 |
For details and further investigation, click here
