| Full name: poly(A) binding protein interacting protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5p12 | ||
| Entrez ID: 10605 | HGNC ID: HGNC:16945 | Ensembl Gene: ENSG00000172239 | OMIM ID: 605184 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PAIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAIP1 | 10605 | 209063_x_at | 0.1916 | 0.4977 | |
| GSE20347 | PAIP1 | 10605 | 209063_x_at | 0.4773 | 0.0021 | |
| GSE23400 | PAIP1 | 10605 | 209063_x_at | 0.4487 | 0.0000 | |
| GSE26886 | PAIP1 | 10605 | 209063_x_at | 0.7122 | 0.0012 | |
| GSE29001 | PAIP1 | 10605 | 208051_s_at | 0.5259 | 0.0525 | |
| GSE38129 | PAIP1 | 10605 | 209063_x_at | 0.4208 | 0.0002 | |
| GSE45670 | PAIP1 | 10605 | 209063_x_at | 0.2325 | 0.1872 | |
| GSE53622 | PAIP1 | 10605 | 60255 | 0.5606 | 0.0000 | |
| GSE53624 | PAIP1 | 10605 | 60255 | 0.5831 | 0.0000 | |
| GSE63941 | PAIP1 | 10605 | 209063_x_at | -0.1095 | 0.8096 | |
| GSE77861 | PAIP1 | 10605 | 209063_x_at | 0.3245 | 0.1361 | |
| GSE97050 | PAIP1 | 10605 | A_24_P77681 | 0.4287 | 0.1961 | |
| SRP007169 | PAIP1 | 10605 | RNAseq | 0.6576 | 0.2419 | |
| SRP008496 | PAIP1 | 10605 | RNAseq | 0.5790 | 0.0958 | |
| SRP064894 | PAIP1 | 10605 | RNAseq | 0.1765 | 0.2252 | |
| SRP133303 | PAIP1 | 10605 | RNAseq | 0.4735 | 0.0040 | |
| SRP193095 | PAIP1 | 10605 | RNAseq | -0.0127 | 0.9099 | |
| SRP219564 | PAIP1 | 10605 | RNAseq | 0.0452 | 0.8626 | |
| TCGA | PAIP1 | 10605 | RNAseq | 0.1392 | 0.0142 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PAIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAIP1 | 10605 | 10 | 0 | 20 | |
| GSE20123 | PAIP1 | 10605 | 10 | 0 | 20 | |
| GSE43470 | PAIP1 | 10605 | 16 | 0 | 27 | |
| GSE46452 | PAIP1 | 10605 | 5 | 22 | 32 | |
| GSE47630 | PAIP1 | 10605 | 6 | 12 | 22 | |
| GSE54993 | PAIP1 | 10605 | 6 | 3 | 61 | |
| GSE54994 | PAIP1 | 10605 | 24 | 2 | 27 | |
| GSE60625 | PAIP1 | 10605 | 0 | 0 | 11 | |
| GSE74703 | PAIP1 | 10605 | 13 | 0 | 23 | |
| GSE74704 | PAIP1 | 10605 | 9 | 0 | 11 | |
| TCGA | PAIP1 | 10605 | 53 | 6 | 37 |
Total number of gains: 152; Total number of losses: 45; Total Number of normals: 291.
Somatic mutations of PAIP1:
Generating mutation plots.
Highly correlated genes for PAIP1:
Showing top 20/1264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAIP1 | HNRNPUL1 | 0.794941 | 3 | 0 | 3 |
| PAIP1 | MRPS6 | 0.791175 | 3 | 0 | 3 |
| PAIP1 | LRRK1 | 0.78966 | 3 | 0 | 3 |
| PAIP1 | ZNF766 | 0.774316 | 3 | 0 | 3 |
| PAIP1 | KRR1 | 0.767389 | 4 | 0 | 4 |
| PAIP1 | ICK | 0.756371 | 3 | 0 | 3 |
| PAIP1 | MDM2 | 0.751875 | 3 | 0 | 3 |
| PAIP1 | ZCCHC3 | 0.735751 | 3 | 0 | 3 |
| PAIP1 | ZBTB2 | 0.734819 | 4 | 0 | 4 |
| PAIP1 | ZNF121 | 0.733105 | 4 | 0 | 4 |
| PAIP1 | HNRNPA1 | 0.73211 | 4 | 0 | 4 |
| PAIP1 | ZNF250 | 0.73162 | 3 | 0 | 3 |
| PAIP1 | ZNF805 | 0.730967 | 4 | 0 | 4 |
| PAIP1 | PET117 | 0.729692 | 3 | 0 | 3 |
| PAIP1 | UTP23 | 0.729023 | 5 | 0 | 4 |
| PAIP1 | PDCD2L | 0.728079 | 3 | 0 | 3 |
| PAIP1 | MFN2 | 0.726113 | 3 | 0 | 3 |
| PAIP1 | MEX3B | 0.725391 | 3 | 0 | 3 |
| PAIP1 | EIF2D | 0.724302 | 3 | 0 | 3 |
| PAIP1 | RPS19BP1 | 0.724123 | 3 | 0 | 3 |
For details and further investigation, click here
