| Full name: TEA domain transcription factor 2 | Alias Symbol: TEF-4|ETF|TEF4 | ||
| Type: protein-coding gene | Cytoband: 19q13.3 | ||
| Entrez ID: 8463 | HGNC ID: HGNC:11715 | Ensembl Gene: ENSG00000074219 | OMIM ID: 601729 |
| Drug and gene relationship at DGIdb | |||
TEAD2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04390 | Hippo signaling pathway |
Expression of TEAD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TEAD2 | 8463 | 226408_at | 1.0815 | 0.0767 | |
| GSE26886 | TEAD2 | 8463 | 226408_at | 1.4675 | 0.0000 | |
| GSE45670 | TEAD2 | 8463 | 226408_at | 0.4074 | 0.0519 | |
| GSE53622 | TEAD2 | 8463 | 114474 | 0.7346 | 0.0000 | |
| GSE53624 | TEAD2 | 8463 | 114474 | 1.2303 | 0.0000 | |
| GSE63941 | TEAD2 | 8463 | 226408_at | -0.2617 | 0.7077 | |
| GSE77861 | TEAD2 | 8463 | 243766_s_at | -0.0659 | 0.7317 | |
| GSE97050 | TEAD2 | 8463 | A_23_P119344 | 0.0917 | 0.7048 | |
| SRP007169 | TEAD2 | 8463 | RNAseq | 3.9283 | 0.0000 | |
| SRP008496 | TEAD2 | 8463 | RNAseq | 3.5314 | 0.0000 | |
| SRP064894 | TEAD2 | 8463 | RNAseq | 1.3954 | 0.0000 | |
| SRP133303 | TEAD2 | 8463 | RNAseq | 1.0889 | 0.0000 | |
| SRP159526 | TEAD2 | 8463 | RNAseq | 1.5927 | 0.0000 | |
| SRP193095 | TEAD2 | 8463 | RNAseq | 1.9289 | 0.0000 | |
| SRP219564 | TEAD2 | 8463 | RNAseq | 0.2713 | 0.6727 | |
| TCGA | TEAD2 | 8463 | RNAseq | 0.0369 | 0.6515 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by TEAD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TEAD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TEAD2 | 8463 | 4 | 4 | 22 | |
| GSE20123 | TEAD2 | 8463 | 4 | 3 | 23 | |
| GSE43470 | TEAD2 | 8463 | 4 | 11 | 28 | |
| GSE46452 | TEAD2 | 8463 | 45 | 1 | 13 | |
| GSE47630 | TEAD2 | 8463 | 10 | 6 | 24 | |
| GSE54993 | TEAD2 | 8463 | 17 | 4 | 49 | |
| GSE54994 | TEAD2 | 8463 | 4 | 14 | 35 | |
| GSE60625 | TEAD2 | 8463 | 9 | 0 | 2 | |
| GSE74703 | TEAD2 | 8463 | 4 | 7 | 25 | |
| GSE74704 | TEAD2 | 8463 | 4 | 1 | 15 | |
| TCGA | TEAD2 | 8463 | 15 | 19 | 62 |
Total number of gains: 120; Total number of losses: 70; Total Number of normals: 298.
Somatic mutations of TEAD2:
Generating mutation plots.
Highly correlated genes for TEAD2:
Showing top 20/1193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TEAD2 | DERL3 | 0.803098 | 3 | 0 | 3 |
| TEAD2 | SSBP4 | 0.78835 | 4 | 0 | 4 |
| TEAD2 | IPO9 | 0.787843 | 3 | 0 | 3 |
| TEAD2 | CERS2 | 0.779411 | 4 | 0 | 4 |
| TEAD2 | GGPS1 | 0.77551 | 3 | 0 | 3 |
| TEAD2 | TEAD4 | 0.76655 | 6 | 0 | 6 |
| TEAD2 | SOX18 | 0.765399 | 3 | 0 | 3 |
| TEAD2 | ZNF683 | 0.761779 | 4 | 0 | 3 |
| TEAD2 | ISCA1 | 0.760724 | 3 | 0 | 3 |
| TEAD2 | IGF2R | 0.760588 | 3 | 0 | 3 |
| TEAD2 | EIF3L | 0.757198 | 3 | 0 | 3 |
| TEAD2 | GPR107 | 0.754324 | 3 | 0 | 3 |
| TEAD2 | VSTM4 | 0.750708 | 3 | 0 | 3 |
| TEAD2 | NXT1 | 0.750614 | 4 | 0 | 4 |
| TEAD2 | DNM3 | 0.749884 | 3 | 0 | 3 |
| TEAD2 | SLC39A3 | 0.748883 | 5 | 0 | 5 |
| TEAD2 | TMEM143 | 0.748602 | 3 | 0 | 3 |
| TEAD2 | ZNF496 | 0.747572 | 6 | 0 | 6 |
| TEAD2 | ARMC9 | 0.747446 | 3 | 0 | 3 |
| TEAD2 | DHRSX | 0.74737 | 3 | 0 | 3 |
For details and further investigation, click here
