| Full name: GRAM domain containing 1A | Alias Symbol: FLJ90346 | ||
| Type: protein-coding gene | Cytoband: 19q13.11 | ||
| Entrez ID: 57655 | HGNC ID: HGNC:29305 | Ensembl Gene: ENSG00000089351 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GRAMD1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRAMD1A | 57655 | 224807_at | 0.6636 | 0.2018 | |
| GSE26886 | GRAMD1A | 57655 | 224807_at | 1.5102 | 0.0000 | |
| GSE45670 | GRAMD1A | 57655 | 224807_at | 0.0849 | 0.6192 | |
| GSE53622 | GRAMD1A | 57655 | 104920 | 0.9515 | 0.0000 | |
| GSE53624 | GRAMD1A | 57655 | 15629 | 1.0591 | 0.0000 | |
| GSE63941 | GRAMD1A | 57655 | 224807_at | -0.2139 | 0.7140 | |
| GSE77861 | GRAMD1A | 57655 | 224807_at | 0.6407 | 0.0248 | |
| GSE97050 | GRAMD1A | 57655 | A_23_P56213 | 0.5886 | 0.1133 | |
| SRP007169 | GRAMD1A | 57655 | RNAseq | 1.8983 | 0.0001 | |
| SRP008496 | GRAMD1A | 57655 | RNAseq | 2.3046 | 0.0000 | |
| SRP064894 | GRAMD1A | 57655 | RNAseq | 1.2455 | 0.0000 | |
| SRP133303 | GRAMD1A | 57655 | RNAseq | 0.5431 | 0.0143 | |
| SRP159526 | GRAMD1A | 57655 | RNAseq | 1.4628 | 0.0001 | |
| SRP193095 | GRAMD1A | 57655 | RNAseq | 1.5433 | 0.0000 | |
| SRP219564 | GRAMD1A | 57655 | RNAseq | 0.5470 | 0.1302 | |
| TCGA | GRAMD1A | 57655 | RNAseq | -0.0813 | 0.2438 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by GRAMD1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRAMD1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRAMD1A | 57655 | 6 | 5 | 19 | |
| GSE20123 | GRAMD1A | 57655 | 6 | 4 | 20 | |
| GSE43470 | GRAMD1A | 57655 | 4 | 7 | 32 | |
| GSE46452 | GRAMD1A | 57655 | 48 | 1 | 10 | |
| GSE47630 | GRAMD1A | 57655 | 8 | 6 | 26 | |
| GSE54993 | GRAMD1A | 57655 | 17 | 3 | 50 | |
| GSE54994 | GRAMD1A | 57655 | 9 | 9 | 35 | |
| GSE60625 | GRAMD1A | 57655 | 9 | 0 | 2 | |
| GSE74703 | GRAMD1A | 57655 | 4 | 4 | 28 | |
| GSE74704 | GRAMD1A | 57655 | 6 | 2 | 12 | |
| TCGA | GRAMD1A | 57655 | 21 | 11 | 64 |
Total number of gains: 138; Total number of losses: 52; Total Number of normals: 298.
Somatic mutations of GRAMD1A:
Generating mutation plots.
Highly correlated genes for GRAMD1A:
Showing top 20/1755 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRAMD1A | RAB34 | 0.803665 | 3 | 0 | 3 |
| GRAMD1A | PLEKHG2 | 0.798702 | 3 | 0 | 3 |
| GRAMD1A | NINJ1 | 0.788786 | 5 | 0 | 5 |
| GRAMD1A | ZNF628 | 0.779368 | 3 | 0 | 3 |
| GRAMD1A | PLCB2 | 0.778219 | 3 | 0 | 3 |
| GRAMD1A | SEMA3C | 0.773432 | 4 | 0 | 4 |
| GRAMD1A | WDR81 | 0.768073 | 4 | 0 | 4 |
| GRAMD1A | HEXB | 0.76737 | 6 | 0 | 6 |
| GRAMD1A | PYCR2 | 0.767019 | 3 | 0 | 3 |
| GRAMD1A | PDIA5 | 0.764991 | 3 | 0 | 3 |
| GRAMD1A | TMEM132A | 0.759394 | 4 | 0 | 4 |
| GRAMD1A | NF1 | 0.759296 | 3 | 0 | 3 |
| GRAMD1A | MNT | 0.755343 | 3 | 0 | 3 |
| GRAMD1A | TP53I13 | 0.755283 | 7 | 0 | 6 |
| GRAMD1A | FADS1 | 0.753573 | 3 | 0 | 3 |
| GRAMD1A | HPCAL1 | 0.751906 | 7 | 0 | 7 |
| GRAMD1A | GAS2L1 | 0.751819 | 3 | 0 | 3 |
| GRAMD1A | SLC39A1 | 0.751622 | 3 | 0 | 3 |
| GRAMD1A | CFL1 | 0.750321 | 3 | 0 | 3 |
| GRAMD1A | FNDC3B | 0.74936 | 7 | 0 | 7 |
For details and further investigation, click here
