DCAF7

 

Full name: DDB1 and CUL4 associated factor 7 Alias Symbol: HAN11|SWAN-1
Type: protein-coding gene Cytoband: 17q23.3
Entrez ID: 10238 HGNC ID: HGNC:30915 Ensembl Gene: ENSG00000136485 OMIM ID: 605973
Drug and gene relationship at DGIdb

 

Expression of DCAF7:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DCAF7 10238 224748_at 0.3545 0.3277
GSE20347 DCAF7 10238 221745_at 0.1616 0.2707
GSE23400 DCAF7 10238 221745_at 0.0261 0.6948
GSE26886 DCAF7 10238 224748_at -0.0298 0.9126
GSE29001 DCAF7 10238 221745_at -0.1098 0.7666
GSE38129 DCAF7 10238 221744_at 0.2056 0.0481
GSE45670 DCAF7 10238 224748_at 0.3304 0.0260
GSE53622 DCAF7 10238 34223 0.3852 0.0000
GSE53624 DCAF7 10238 34223 0.5911 0.0000
GSE63941 DCAF7 10238 224748_at 0.3668 0.2316
GSE77861 DCAF7 10238 224748_at 0.6761 0.0291
GSE97050 DCAF7 10238 A_24_P916141 0.0264 0.9096
SRP007169 DCAF7 10238 RNAseq 0.3050 0.3072
SRP008496 DCAF7 10238 RNAseq 0.0574 0.7870
SRP064894 DCAF7 10238 RNAseq 0.6479 0.0000
SRP133303 DCAF7 10238 RNAseq 0.6177 0.0002
SRP159526 DCAF7 10238 RNAseq 0.6075 0.0006
SRP193095 DCAF7 10238 RNAseq 0.3049 0.0015
SRP219564 DCAF7 10238 RNAseq 0.4688 0.0706
TCGA DCAF7 10238 RNAseq 0.0074 0.8605

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by DCAF7 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of DCAF7:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DCAF7 10238 3 1 26
GSE20123 DCAF7 10238 3 1 26
GSE43470 DCAF7 10238 4 0 39
GSE46452 DCAF7 10238 31 0 28
GSE47630 DCAF7 10238 7 1 32
GSE54993 DCAF7 10238 2 5 63
GSE54994 DCAF7 10238 9 5 39
GSE60625 DCAF7 10238 4 0 7
GSE74703 DCAF7 10238 4 0 32
GSE74704 DCAF7 10238 3 1 16
TCGA DCAF7 10238 31 8 57

Total number of gains: 101; Total number of losses: 22; Total Number of normals: 365.  


 

Somatic mutations of DCAF7:

 

Generating mutation plots.

 

Highly correlated genes for DCAF7:

 

Showing top 20/855 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DCAF7DEDD0.759027303
DCAF7C17orf800.74685707
DCAF7NOM10.74668303
DCAF7DGCR20.744395303
DCAF7TCP10.734993303
DCAF7LRRCC10.733423303
DCAF7COG20.72918404
DCAF7FTSJ30.728436504
DCAF7UGGT20.728122303
DCAF7DEGS10.715756303
DCAF7SSBP40.714444303
DCAF7PTCD10.711615303
DCAF7RAB340.710933303
DCAF7ZCCHC30.702991504
DCAF7ZDHHC140.702564303
DCAF7NINJ10.700765303
DCAF7NEDD10.699357504
DCAF7DPF20.696978403
DCAF7FAM32A0.695926303
DCAF7ZNF1420.693196303

For details and further investigation, click here