| Full name: peptide YY | Alias Symbol: PYY1 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 5697 | HGNC ID: HGNC:9748 | Ensembl Gene: ENSG00000131096 | OMIM ID: 600781 |
| Drug and gene relationship at DGIdb | |||
Expression of PYY:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PYY | 5697 | 211253_x_at | -0.0173 | 0.9655 | |
| GSE20347 | PYY | 5697 | 211253_x_at | -0.0563 | 0.4983 | |
| GSE23400 | PYY | 5697 | 211253_x_at | -0.0690 | 0.1068 | |
| GSE26886 | PYY | 5697 | 211253_x_at | 0.1192 | 0.5638 | |
| GSE29001 | PYY | 5697 | 211253_x_at | -0.0887 | 0.6224 | |
| GSE38129 | PYY | 5697 | 211253_x_at | -0.1587 | 0.0577 | |
| GSE45670 | PYY | 5697 | 211253_x_at | -0.0511 | 0.6882 | |
| GSE53622 | PYY | 5697 | 86231 | 0.2772 | 0.0000 | |
| GSE53624 | PYY | 5697 | 86231 | 0.1215 | 0.1061 | |
| GSE63941 | PYY | 5697 | 211253_x_at | 0.1217 | 0.5052 | |
| GSE77861 | PYY | 5697 | 211253_x_at | -0.0742 | 0.6618 | |
| GSE97050 | PYY | 5697 | A_33_P3329958 | -0.0582 | 0.8862 | |
| TCGA | PYY | 5697 | RNAseq | -1.2088 | 0.3535 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PYY expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PYY:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PYY | 5697 | 5 | 2 | 23 | |
| GSE20123 | PYY | 5697 | 5 | 2 | 23 | |
| GSE43470 | PYY | 5697 | 1 | 2 | 40 | |
| GSE46452 | PYY | 5697 | 32 | 0 | 27 | |
| GSE47630 | PYY | 5697 | 9 | 0 | 31 | |
| GSE54993 | PYY | 5697 | 3 | 4 | 63 | |
| GSE54994 | PYY | 5697 | 8 | 6 | 39 | |
| GSE60625 | PYY | 5697 | 4 | 0 | 7 | |
| GSE74703 | PYY | 5697 | 1 | 1 | 34 | |
| GSE74704 | PYY | 5697 | 3 | 1 | 16 | |
| TCGA | PYY | 5697 | 23 | 7 | 66 |
Total number of gains: 94; Total number of losses: 25; Total Number of normals: 369.
Somatic mutations of PYY:
Generating mutation plots.
Highly correlated genes for PYY:
Showing top 20/256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PYY | CC2D2B | 0.757735 | 3 | 0 | 3 |
| PYY | OSGIN1 | 0.693099 | 3 | 0 | 3 |
| PYY | PURB | 0.687138 | 3 | 0 | 3 |
| PYY | SOX1 | 0.685624 | 4 | 0 | 3 |
| PYY | CD1B | 0.674912 | 3 | 0 | 3 |
| PYY | CDK15 | 0.666605 | 3 | 0 | 3 |
| PYY | SYPL2 | 0.663971 | 3 | 0 | 3 |
| PYY | SIGLEC5 | 0.661098 | 3 | 0 | 3 |
| PYY | DPYSL5 | 0.654151 | 3 | 0 | 3 |
| PYY | ZFHX4-AS1 | 0.649696 | 3 | 0 | 3 |
| PYY | NXF3 | 0.649091 | 4 | 0 | 4 |
| PYY | BMP15 | 0.644914 | 5 | 0 | 4 |
| PYY | MESP1 | 0.641549 | 3 | 0 | 3 |
| PYY | TMEM235 | 0.640636 | 5 | 0 | 5 |
| PYY | RAP1GAP | 0.635418 | 4 | 0 | 4 |
| PYY | BPIFB4 | 0.631205 | 3 | 0 | 3 |
| PYY | FBXL19-AS1 | 0.628232 | 3 | 0 | 3 |
| PYY | GSTM5 | 0.627847 | 3 | 0 | 3 |
| PYY | CROCC | 0.626285 | 4 | 0 | 4 |
| PYY | IGFN1 | 0.625272 | 4 | 0 | 4 |
For details and further investigation, click here
