| Full name: T cell leukemia/lymphoma 6 | Alias Symbol: TCL6e1|TNG2|TNG1 | ||
| Type: non-coding RNA | Cytoband: 14q32.13 | ||
| Entrez ID: 27004 | HGNC ID: HGNC:13463 | Ensembl Gene: ENSG00000187621 | OMIM ID: 604412 |
| Drug and gene relationship at DGIdb | |||
Expression of TCL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TCL6 | 27004 | 239964_at | -0.1854 | 0.3890 | |
| GSE20347 | TCL6 | 27004 | 207894_s_at | 0.0140 | 0.8627 | |
| GSE23400 | TCL6 | 27004 | 219840_s_at | 0.0136 | 0.5904 | |
| GSE26886 | TCL6 | 27004 | 239964_at | -0.3183 | 0.0085 | |
| GSE29001 | TCL6 | 27004 | 221624_at | -0.0949 | 0.5791 | |
| GSE38129 | TCL6 | 27004 | 207894_s_at | -0.0541 | 0.6005 | |
| GSE45670 | TCL6 | 27004 | 239964_at | -0.0338 | 0.7713 | |
| GSE53622 | TCL6 | 27004 | 104757 | -0.0406 | 0.6583 | |
| GSE53624 | TCL6 | 27004 | 104757 | -0.1724 | 0.0628 | |
| GSE63941 | TCL6 | 27004 | 239964_at | 0.3561 | 0.0700 | |
| GSE77861 | TCL6 | 27004 | 239964_at | -0.2114 | 0.0600 | |
| SRP133303 | TCL6 | 27004 | RNAseq | 0.1910 | 0.3916 | |
| SRP193095 | TCL6 | 27004 | RNAseq | -0.0179 | 0.9333 | |
| TCGA | TCL6 | 27004 | RNAseq | 0.9575 | 0.2728 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TCL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCL6 | 27004 | 10 | 4 | 16 | |
| GSE20123 | TCL6 | 27004 | 10 | 3 | 17 | |
| GSE43470 | TCL6 | 27004 | 8 | 3 | 32 | |
| GSE46452 | TCL6 | 27004 | 16 | 3 | 40 | |
| GSE47630 | TCL6 | 27004 | 11 | 8 | 21 | |
| GSE54993 | TCL6 | 27004 | 3 | 8 | 59 | |
| GSE54994 | TCL6 | 27004 | 21 | 4 | 28 | |
| GSE60625 | TCL6 | 27004 | 0 | 2 | 9 | |
| GSE74703 | TCL6 | 27004 | 6 | 3 | 27 | |
| GSE74704 | TCL6 | 27004 | 6 | 3 | 11 | |
| TCGA | TCL6 | 27004 | 30 | 19 | 47 |
Total number of gains: 121; Total number of losses: 60; Total Number of normals: 307.
Somatic mutations of TCL6:
Generating mutation plots.
Highly correlated genes for TCL6:
Showing top 20/1154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCL6 | EFR3B | 0.80682 | 3 | 0 | 3 |
| TCL6 | EPO | 0.777433 | 3 | 0 | 3 |
| TCL6 | RFX2 | 0.753182 | 3 | 0 | 3 |
| TCL6 | KIR2DS3 | 0.74597 | 3 | 0 | 3 |
| TCL6 | ARVCF | 0.743509 | 3 | 0 | 3 |
| TCL6 | ZNF835 | 0.726921 | 3 | 0 | 3 |
| TCL6 | CNTNAP1 | 0.726832 | 3 | 0 | 3 |
| TCL6 | MROH6 | 0.721974 | 3 | 0 | 3 |
| TCL6 | CRHR2 | 0.718401 | 4 | 0 | 4 |
| TCL6 | FRAS1 | 0.716618 | 4 | 0 | 4 |
| TCL6 | CACNG1 | 0.712809 | 3 | 0 | 3 |
| TCL6 | AQP6 | 0.708354 | 5 | 0 | 4 |
| TCL6 | ESAM | 0.702665 | 3 | 0 | 3 |
| TCL6 | KCNS1 | 0.702494 | 4 | 0 | 3 |
| TCL6 | HPX | 0.701222 | 5 | 0 | 4 |
| TCL6 | GP2 | 0.699976 | 5 | 0 | 5 |
| TCL6 | C16orf70 | 0.698821 | 3 | 0 | 3 |
| TCL6 | HUNK | 0.697984 | 3 | 0 | 3 |
| TCL6 | FOXP3 | 0.695811 | 4 | 0 | 4 |
| TCL6 | CATSPERG | 0.69536 | 3 | 0 | 3 |
For details and further investigation, click here
