| Full name: HOXA distal transcript antisense RNA | Alias Symbol: HOXA-AS6|RP1-170O19.3|HOXA13-AS1 | ||
| Type: non-coding RNA | Cytoband: 7p15.2 | ||
| Entrez ID: 100316868 | HGNC ID: HGNC:37461 | Ensembl Gene: ENSG00000243766 | OMIM ID: 614060 |
| Drug and gene relationship at DGIdb | |||
Expression of HOTTIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOTTIP | 100316868 | 1564069_at | -0.0779 | 0.7648 | |
| GSE26886 | HOTTIP | 100316868 | 1564069_at | -0.1000 | 0.6418 | |
| GSE45670 | HOTTIP | 100316868 | 1564069_at | -0.1255 | 0.2208 | |
| GSE53622 | HOTTIP | 100316868 | 104212 | -0.2450 | 0.0182 | |
| GSE53624 | HOTTIP | 100316868 | 104212 | -0.1160 | 0.0801 | |
| GSE63941 | HOTTIP | 100316868 | 1564069_at | 0.3620 | 0.0155 | |
| GSE77861 | HOTTIP | 100316868 | 1564069_at | -0.2817 | 0.2729 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HOTTIP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of HOTTIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOTTIP | 100316868 | 16 | 1 | 13 | |
| GSE20123 | HOTTIP | 100316868 | 16 | 1 | 13 | |
| GSE43470 | HOTTIP | 100316868 | 4 | 0 | 39 | |
| GSE46452 | HOTTIP | 100316868 | 10 | 2 | 47 | |
| GSE47630 | HOTTIP | 100316868 | 8 | 1 | 31 | |
| GSE54993 | HOTTIP | 100316868 | 0 | 6 | 64 | |
| GSE54994 | HOTTIP | 100316868 | 21 | 2 | 30 | |
| GSE60625 | HOTTIP | 100316868 | 0 | 0 | 11 | |
| GSE74703 | HOTTIP | 100316868 | 4 | 0 | 32 | |
| GSE74704 | HOTTIP | 100316868 | 10 | 1 | 9 | |
| TCGA | HOTTIP | 100316868 | 55 | 6 | 35 |
Total number of gains: 144; Total number of losses: 20; Total Number of normals: 324.
Somatic mutations of HOTTIP:
Generating mutation plots.
Highly correlated genes for HOTTIP:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOTTIP | CC2D2B | 0.761754 | 3 | 0 | 3 |
| HOTTIP | WNT6 | 0.716032 | 3 | 0 | 3 |
| HOTTIP | LRRC25 | 0.706734 | 3 | 0 | 3 |
| HOTTIP | PSG1 | 0.672238 | 3 | 0 | 3 |
| HOTTIP | DPYSL5 | 0.662759 | 3 | 0 | 3 |
| HOTTIP | ASB12 | 0.660749 | 4 | 0 | 3 |
| HOTTIP | KLHL30-AS1 | 0.660455 | 3 | 0 | 3 |
| HOTTIP | MROH2A | 0.654249 | 3 | 0 | 3 |
| HOTTIP | KCNJ3 | 0.653769 | 3 | 0 | 3 |
| HOTTIP | NKX1-1 | 0.652923 | 4 | 0 | 4 |
| HOTTIP | GNAO1 | 0.644554 | 3 | 0 | 3 |
| HOTTIP | GML | 0.638413 | 4 | 0 | 3 |
| HOTTIP | C10orf53 | 0.637909 | 3 | 0 | 3 |
| HOTTIP | MAP3K19 | 0.626754 | 4 | 0 | 3 |
| HOTTIP | DLGAP1 | 0.622162 | 3 | 0 | 3 |
| HOTTIP | EFCAB5 | 0.616029 | 4 | 0 | 3 |
| HOTTIP | ACACB | 0.615272 | 3 | 0 | 3 |
| HOTTIP | CAMK2A | 0.614441 | 4 | 0 | 3 |
| HOTTIP | SYT2 | 0.614225 | 3 | 0 | 3 |
| HOTTIP | KCNG4 | 0.609824 | 5 | 0 | 3 |
For details and further investigation, click here
