| Full name: dermatan sulfate epimerase like | Alias Symbol: NCAG1|FLJ11477|DE-epi2 | ||
| Type: protein-coding gene | Cytoband: 18q22.1 | ||
| Entrez ID: 92126 | HGNC ID: HGNC:18144 | Ensembl Gene: ENSG00000171451 | OMIM ID: 611125 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DSEL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DSEL | 92126 | 232235_at | -0.4220 | 0.6005 | |
| GSE26886 | DSEL | 92126 | 232235_at | 0.9165 | 0.0159 | |
| GSE45670 | DSEL | 92126 | 232235_at | -1.3282 | 0.0074 | |
| GSE53622 | DSEL | 92126 | 77064 | 0.0109 | 0.9504 | |
| GSE53624 | DSEL | 92126 | 77064 | 0.0802 | 0.7174 | |
| GSE63941 | DSEL | 92126 | 232235_at | -5.6703 | 0.0003 | |
| GSE77861 | DSEL | 92126 | 244852_at | 0.0342 | 0.7192 | |
| GSE97050 | DSEL | 92126 | A_33_P3251841 | -0.2198 | 0.6156 | |
| SRP007169 | DSEL | 92126 | RNAseq | 1.8435 | 0.0011 | |
| SRP008496 | DSEL | 92126 | RNAseq | 2.4085 | 0.0000 | |
| SRP064894 | DSEL | 92126 | RNAseq | 0.6260 | 0.0368 | |
| SRP133303 | DSEL | 92126 | RNAseq | 0.6190 | 0.0315 | |
| SRP159526 | DSEL | 92126 | RNAseq | 0.8439 | 0.0840 | |
| SRP193095 | DSEL | 92126 | RNAseq | 0.6907 | 0.0001 | |
| SRP219564 | DSEL | 92126 | RNAseq | 0.7191 | 0.1548 | |
| TCGA | DSEL | 92126 | RNAseq | -0.3637 | 0.0084 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by DSEL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DSEL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DSEL | 92126 | 0 | 10 | 20 | |
| GSE20123 | DSEL | 92126 | 0 | 10 | 20 | |
| GSE43470 | DSEL | 92126 | 1 | 7 | 35 | |
| GSE46452 | DSEL | 92126 | 1 | 26 | 32 | |
| GSE47630 | DSEL | 92126 | 5 | 21 | 14 | |
| GSE54993 | DSEL | 92126 | 9 | 0 | 61 | |
| GSE54994 | DSEL | 92126 | 1 | 18 | 34 | |
| GSE60625 | DSEL | 92126 | 0 | 4 | 7 | |
| GSE74703 | DSEL | 92126 | 1 | 7 | 28 | |
| GSE74704 | DSEL | 92126 | 0 | 8 | 12 | |
| TCGA | DSEL | 92126 | 8 | 46 | 42 |
Total number of gains: 26; Total number of losses: 157; Total Number of normals: 305.
Somatic mutations of DSEL:
Generating mutation plots.
Highly correlated genes for DSEL:
Showing top 20/877 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DSEL | SMPD1 | 0.833124 | 3 | 0 | 3 |
| DSEL | NTAN1 | 0.792996 | 3 | 0 | 3 |
| DSEL | LRRK2 | 0.772599 | 3 | 0 | 3 |
| DSEL | RAPGEF2 | 0.771393 | 4 | 0 | 4 |
| DSEL | FAM98B | 0.767999 | 3 | 0 | 3 |
| DSEL | NFIC | 0.763886 | 3 | 0 | 3 |
| DSEL | DCHS1 | 0.759424 | 5 | 0 | 5 |
| DSEL | DZIP1L | 0.747543 | 3 | 0 | 3 |
| DSEL | ZNF225 | 0.741444 | 3 | 0 | 3 |
| DSEL | TYW3 | 0.739478 | 3 | 0 | 3 |
| DSEL | PRKG1 | 0.737463 | 7 | 0 | 7 |
| DSEL | PDE5A | 0.736537 | 4 | 0 | 4 |
| DSEL | PEG3 | 0.735531 | 4 | 0 | 4 |
| DSEL | TRPC6 | 0.730247 | 4 | 0 | 4 |
| DSEL | RAB11FIP5 | 0.728806 | 3 | 0 | 3 |
| DSEL | ZNF322 | 0.727539 | 3 | 0 | 3 |
| DSEL | SLC30A5 | 0.720447 | 3 | 0 | 3 |
| DSEL | PAMR1 | 0.720409 | 5 | 0 | 5 |
| DSEL | C16orf72 | 0.719425 | 3 | 0 | 3 |
| DSEL | CD93 | 0.718433 | 5 | 0 | 5 |
For details and further investigation, click here
