| Full name: family with sequence similarity 98 member B | Alias Symbol: FLJ38426 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 283742 | HGNC ID: HGNC:26773 | Ensembl Gene: ENSG00000171262 | OMIM ID: 616142 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FAM98B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM98B | 283742 | 225086_at | -0.1390 | 0.8182 | |
| GSE26886 | FAM98B | 283742 | 225086_at | 0.1170 | 0.6499 | |
| GSE45670 | FAM98B | 283742 | 225086_at | -0.0987 | 0.5161 | |
| GSE53622 | FAM98B | 283742 | 28242 | -0.0608 | 0.4587 | |
| GSE53624 | FAM98B | 283742 | 28242 | 0.3009 | 0.0000 | |
| GSE63941 | FAM98B | 283742 | 225086_at | -1.0081 | 0.0157 | |
| GSE77861 | FAM98B | 283742 | 225086_at | 0.1148 | 0.7603 | |
| GSE97050 | FAM98B | 283742 | A_33_P3378772 | -0.3658 | 0.3074 | |
| SRP007169 | FAM98B | 283742 | RNAseq | 0.7085 | 0.1228 | |
| SRP008496 | FAM98B | 283742 | RNAseq | 0.6965 | 0.0531 | |
| SRP064894 | FAM98B | 283742 | RNAseq | 0.1068 | 0.4751 | |
| SRP133303 | FAM98B | 283742 | RNAseq | 0.4283 | 0.0147 | |
| SRP159526 | FAM98B | 283742 | RNAseq | 0.4135 | 0.0959 | |
| SRP193095 | FAM98B | 283742 | RNAseq | 0.0597 | 0.6156 | |
| SRP219564 | FAM98B | 283742 | RNAseq | -0.0731 | 0.8440 | |
| TCGA | FAM98B | 283742 | RNAseq | 0.1156 | 0.1195 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FAM98B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM98B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM98B | 283742 | 2 | 7 | 21 | |
| GSE20123 | FAM98B | 283742 | 2 | 7 | 21 | |
| GSE43470 | FAM98B | 283742 | 4 | 5 | 34 | |
| GSE46452 | FAM98B | 283742 | 3 | 7 | 49 | |
| GSE47630 | FAM98B | 283742 | 8 | 11 | 21 | |
| GSE54993 | FAM98B | 283742 | 4 | 6 | 60 | |
| GSE54994 | FAM98B | 283742 | 5 | 7 | 41 | |
| GSE60625 | FAM98B | 283742 | 4 | 0 | 7 | |
| GSE74703 | FAM98B | 283742 | 4 | 4 | 28 | |
| GSE74704 | FAM98B | 283742 | 1 | 5 | 14 | |
| TCGA | FAM98B | 283742 | 11 | 18 | 67 |
Total number of gains: 48; Total number of losses: 77; Total Number of normals: 363.
Somatic mutations of FAM98B:
Generating mutation plots.
Highly correlated genes for FAM98B:
Showing top 20/412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM98B | SRSF6 | 0.859991 | 3 | 0 | 3 |
| FAM98B | MAPK1 | 0.813426 | 3 | 0 | 3 |
| FAM98B | PRICKLE2 | 0.811825 | 3 | 0 | 3 |
| FAM98B | MXRA7 | 0.809153 | 3 | 0 | 3 |
| FAM98B | KLHL13 | 0.799688 | 3 | 0 | 3 |
| FAM98B | RBM7 | 0.784079 | 3 | 0 | 3 |
| FAM98B | TBC1D19 | 0.778703 | 3 | 0 | 3 |
| FAM98B | DSEL | 0.767999 | 3 | 0 | 3 |
| FAM98B | ATL1 | 0.764073 | 3 | 0 | 3 |
| FAM98B | ACSS3 | 0.763665 | 3 | 0 | 3 |
| FAM98B | MACF1 | 0.758927 | 3 | 0 | 3 |
| FAM98B | PYGO1 | 0.753288 | 3 | 0 | 3 |
| FAM98B | SYNC | 0.751904 | 3 | 0 | 3 |
| FAM98B | HYLS1 | 0.74712 | 3 | 0 | 3 |
| FAM98B | CAND1 | 0.745108 | 3 | 0 | 3 |
| FAM98B | EML1 | 0.743174 | 3 | 0 | 3 |
| FAM98B | MCAM | 0.741146 | 3 | 0 | 3 |
| FAM98B | TMEM30A | 0.740555 | 4 | 0 | 4 |
| FAM98B | HSPA12A | 0.738306 | 3 | 0 | 3 |
| FAM98B | SSBP3 | 0.737059 | 3 | 0 | 3 |
For details and further investigation, click here
