C16orf72

 

Full name: chromosome 16 open reading frame 72 Alias Symbol: FLJ41272|PRO0149
Type: protein-coding gene Cytoband: 16p13.2
Entrez ID: 29035 HGNC ID: HGNC:30103 Ensembl Gene: ENSG00000182831 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of C16orf72:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C16orf72 29035 225183_at -0.4764 0.6705
GSE26886 C16orf72 29035 225183_at -0.8227 0.0000
GSE45670 C16orf72 29035 225183_at -0.0630 0.6898
GSE53622 C16orf72 29035 16902 -0.1347 0.0582
GSE53624 C16orf72 29035 16902 -0.0613 0.3851
GSE63941 C16orf72 29035 225183_at -0.6008 0.1457
GSE77861 C16orf72 29035 225183_at -0.3882 0.3005
GSE97050 C16orf72 29035 A_32_P4403 0.0515 0.8593
SRP007169 C16orf72 29035 RNAseq -1.0023 0.0079
SRP008496 C16orf72 29035 RNAseq -0.8661 0.0000
SRP064894 C16orf72 29035 RNAseq -0.5313 0.0004
SRP133303 C16orf72 29035 RNAseq 0.2697 0.0427
SRP159526 C16orf72 29035 RNAseq -0.4018 0.2738
SRP193095 C16orf72 29035 RNAseq -0.2053 0.1034
SRP219564 C16orf72 29035 RNAseq -0.5321 0.0806
TCGA C16orf72 29035 RNAseq -0.0159 0.7321

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by C16orf72 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C16orf72:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C16orf72 29035 4 4 22
GSE20123 C16orf72 29035 4 3 23
GSE43470 C16orf72 29035 3 2 38
GSE46452 C16orf72 29035 38 1 20
GSE47630 C16orf72 29035 13 6 21
GSE54993 C16orf72 29035 3 5 62
GSE54994 C16orf72 29035 5 9 39
GSE60625 C16orf72 29035 4 0 7
GSE74703 C16orf72 29035 3 2 31
GSE74704 C16orf72 29035 2 1 17
TCGA C16orf72 29035 21 12 63

Total number of gains: 100; Total number of losses: 45; Total Number of normals: 343.  


 

Somatic mutations of C16orf72:

 

Generating mutation plots.

 

Highly correlated genes for C16orf72:

 

Showing top 20/530 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C16orf72HIPK10.813124303
C16orf72GLUD20.788292303
C16orf72ESYT20.781388303
C16orf72RRN30.780996303
C16orf72PLEKHM30.776044303
C16orf72HSPA40.772133303
C16orf72APC0.76742303
C16orf72ZFC3H10.760373303
C16orf72IKZF50.759471303
C16orf72HIBCH0.75431303
C16orf72JAG10.744455303
C16orf72UBE2B0.737641303
C16orf72OSTF10.735704303
C16orf72SLC39A20.7314303
C16orf72CHMP50.727874404
C16orf72CAPNS20.72483303
C16orf72KCTD100.722356404
C16orf72RBBP60.721156303
C16orf72LYSMD30.720669505
C16orf72DSEL0.719425303

For details and further investigation, click here