| Full name: tRNA-yW synthesizing protein 3 homolog | Alias Symbol: FLJ40918 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 127253 | HGNC ID: HGNC:24757 | Ensembl Gene: ENSG00000162623 | OMIM ID: 611245 |
| Drug and gene relationship at DGIdb | |||
Expression of TYW3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TYW3 | 127253 | 227141_at | -0.0956 | 0.8262 | |
| GSE26886 | TYW3 | 127253 | 227141_at | 0.3031 | 0.1470 | |
| GSE45670 | TYW3 | 127253 | 227141_at | 0.2664 | 0.1782 | |
| GSE53622 | TYW3 | 127253 | 29443 | -0.2398 | 0.0031 | |
| GSE53624 | TYW3 | 127253 | 29443 | -0.1199 | 0.2718 | |
| GSE63941 | TYW3 | 127253 | 227141_at | 0.2507 | 0.5255 | |
| GSE77861 | TYW3 | 127253 | 227141_at | -0.0494 | 0.8510 | |
| GSE97050 | TYW3 | 127253 | A_24_P396327 | -0.7173 | 0.0976 | |
| SRP007169 | TYW3 | 127253 | RNAseq | 0.7029 | 0.1204 | |
| SRP008496 | TYW3 | 127253 | RNAseq | 0.6778 | 0.0468 | |
| SRP064894 | TYW3 | 127253 | RNAseq | -0.1368 | 0.3338 | |
| SRP133303 | TYW3 | 127253 | RNAseq | 0.0912 | 0.5003 | |
| SRP159526 | TYW3 | 127253 | RNAseq | -0.1895 | 0.3921 | |
| SRP193095 | TYW3 | 127253 | RNAseq | -0.2814 | 0.0112 | |
| SRP219564 | TYW3 | 127253 | RNAseq | -0.3713 | 0.3323 | |
| TCGA | TYW3 | 127253 | RNAseq | -0.1905 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TYW3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TYW3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TYW3 | 127253 | 0 | 7 | 23 | |
| GSE20123 | TYW3 | 127253 | 0 | 7 | 23 | |
| GSE43470 | TYW3 | 127253 | 4 | 2 | 37 | |
| GSE46452 | TYW3 | 127253 | 0 | 1 | 58 | |
| GSE47630 | TYW3 | 127253 | 8 | 6 | 26 | |
| GSE54993 | TYW3 | 127253 | 0 | 0 | 70 | |
| GSE54994 | TYW3 | 127253 | 6 | 4 | 43 | |
| GSE60625 | TYW3 | 127253 | 0 | 0 | 11 | |
| GSE74703 | TYW3 | 127253 | 3 | 2 | 31 | |
| GSE74704 | TYW3 | 127253 | 0 | 4 | 16 | |
| TCGA | TYW3 | 127253 | 9 | 23 | 64 |
Total number of gains: 30; Total number of losses: 56; Total Number of normals: 402.
Somatic mutations of TYW3:
Generating mutation plots.
Highly correlated genes for TYW3:
Showing top 20/325 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TYW3 | PAIP2 | 0.847194 | 3 | 0 | 3 |
| TYW3 | CHM | 0.818398 | 3 | 0 | 3 |
| TYW3 | HCCS | 0.776154 | 3 | 0 | 3 |
| TYW3 | PDS5B | 0.771626 | 3 | 0 | 3 |
| TYW3 | LARP7 | 0.763001 | 3 | 0 | 3 |
| TYW3 | AMD1 | 0.762775 | 3 | 0 | 3 |
| TYW3 | THAP2 | 0.761406 | 3 | 0 | 3 |
| TYW3 | CUL2 | 0.756788 | 3 | 0 | 3 |
| TYW3 | CPE | 0.756137 | 3 | 0 | 3 |
| TYW3 | RMND1 | 0.755167 | 3 | 0 | 3 |
| TYW3 | IGDCC4 | 0.751256 | 3 | 0 | 3 |
| TYW3 | TMX3 | 0.751061 | 3 | 0 | 3 |
| TYW3 | AXL | 0.748392 | 3 | 0 | 3 |
| TYW3 | TM4SF18 | 0.745803 | 3 | 0 | 3 |
| TYW3 | VPS26A | 0.744684 | 3 | 0 | 3 |
| TYW3 | RAB8B | 0.742864 | 4 | 0 | 3 |
| TYW3 | CHD1 | 0.741663 | 3 | 0 | 3 |
| TYW3 | DSEL | 0.739478 | 3 | 0 | 3 |
| TYW3 | TSPAN4 | 0.738825 | 3 | 0 | 3 |
| TYW3 | CDC123 | 0.738399 | 3 | 0 | 3 |
For details and further investigation, click here
