| Full name: eukaryotic translation initiation factor 5A like 1 | Alias Symbol: bA342M3.3 | ||
| Type: protein-coding gene | Cytoband: 10q22.3 | ||
| Entrez ID: 143244 | HGNC ID: HGNC:17419 | Ensembl Gene: ENSG00000253626 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of EIF5AL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | EIF5AL1 | 143244 | 16104 | 0.1411 | 0.6011 | |
| GSE53624 | EIF5AL1 | 143244 | 16104 | 0.1301 | 0.5066 | |
| SRP007169 | EIF5AL1 | 143244 | RNAseq | -0.1028 | 0.8827 | |
| SRP133303 | EIF5AL1 | 143244 | RNAseq | -0.0325 | 0.8796 | |
| SRP193095 | EIF5AL1 | 143244 | RNAseq | 0.1664 | 0.4016 | |
| SRP219564 | EIF5AL1 | 143244 | RNAseq | 0.0384 | 0.9299 | |
| TCGA | EIF5AL1 | 143244 | RNAseq | 0.2643 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF5AL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF5AL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF5AL1 | 143244 | 2 | 5 | 23 | |
| GSE20123 | EIF5AL1 | 143244 | 2 | 4 | 24 | |
| GSE43470 | EIF5AL1 | 143244 | 1 | 7 | 35 | |
| GSE46452 | EIF5AL1 | 143244 | 0 | 11 | 48 | |
| GSE47630 | EIF5AL1 | 143244 | 2 | 14 | 24 | |
| GSE54993 | EIF5AL1 | 143244 | 7 | 0 | 63 | |
| GSE54994 | EIF5AL1 | 143244 | 1 | 11 | 41 | |
| GSE60625 | EIF5AL1 | 143244 | 0 | 0 | 11 | |
| GSE74703 | EIF5AL1 | 143244 | 1 | 4 | 31 | |
| GSE74704 | EIF5AL1 | 143244 | 1 | 2 | 17 | |
| TCGA | EIF5AL1 | 143244 | 10 | 24 | 62 |
Total number of gains: 27; Total number of losses: 82; Total Number of normals: 379.
Somatic mutations of EIF5AL1:
Generating mutation plots.
Highly correlated genes for EIF5AL1:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF5AL1 | DEFB128 | 0.741446 | 3 | 0 | 3 |
| EIF5AL1 | SPEG | 0.670463 | 3 | 0 | 3 |
| EIF5AL1 | TCF23 | 0.65733 | 3 | 0 | 3 |
| EIF5AL1 | OR5F1 | 0.633239 | 3 | 0 | 3 |
| EIF5AL1 | OR10A2 | 0.625357 | 3 | 0 | 3 |
| EIF5AL1 | TIGD1 | 0.612335 | 3 | 0 | 3 |
| EIF5AL1 | KRTAP10-3 | 0.597268 | 3 | 0 | 3 |
| EIF5AL1 | TTLL2 | 0.59061 | 3 | 0 | 3 |
| EIF5AL1 | GSG1 | 0.577148 | 3 | 0 | 3 |
| EIF5AL1 | SEZ6 | 0.575207 | 3 | 0 | 3 |
| EIF5AL1 | FAM30A | 0.566503 | 3 | 0 | 3 |
| EIF5AL1 | RAX2 | 0.565106 | 3 | 0 | 3 |
| EIF5AL1 | CABP5 | 0.558127 | 3 | 0 | 3 |
| EIF5AL1 | LGALS12 | 0.554214 | 3 | 0 | 3 |
| EIF5AL1 | KCTD19 | 0.552837 | 3 | 0 | 3 |
| EIF5AL1 | KRTAP21-2 | 0.537261 | 3 | 0 | 3 |
For details and further investigation, click here
